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Gene · 54

ACP5: acid phosphatase 5, tartrate resistant

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. ACP5: acid phosphatase 5, tartrate resistant. Genes, record 54. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/54

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Gene

Symbol
ACP5
HGNC
Name
acid phosphatase 5, tartrate resistant
HGNC
NCBI Gene ID
54
NCBI Gene
HGNC ID
HGNC:124
HGNC
Ensembl
ENSG00000102575
NCBI Gene
Aliases
HPAP, TRACP5a, TRACP5b, TRAP, TRAcP, TrATPase
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P13686Tartrate-resistant acid phosphatase type 53252Ensembl, GeneID, HGNC

Source UniProt

Patents117

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1436031P13686Espacenet
JP 2026004568 A2026-01-1436032P13686Espacenet
JP 2026004568 A2026-01-1436033P13686Espacenet
JP 2026004568 A2026-01-1436034P13686Espacenet
JP 2025172069 A2025-11-20152P13686Espacenet
JP 2025172069 A2025-11-20153P13686Espacenet
JP 2025172069 A2025-11-20154P13686Espacenet
JP 2025172069 A2025-11-20159P13686Espacenet
EP 4650780 A22025-11-19426P13686Espacenet
JP 2025147176 A2025-10-06147P13686Espacenet

1 to 10 of 117

See all 117 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants947

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleACP5 papersNewest fiscal year
ZIAAI001220Pathogenesis, and Outcome of Autoinflammatory Diseases, NOMID/CAPS, DIRA, CANDLE, SAVI, NLRC4-MAS, Still's-like Diseases, and other Undifferentiated Autoinflammatory Diseases52025
ZIAAI000646Transgenic Animal Models Of Human Immune Defects42025
ZIAAI000647Genes And Gene Products As Immunoadjuvants42025
P30CA014195Cancer Center Support Grant (CCSG)32025
P30CA014520UW Comprehensive Cancer Center Support32025
P30CA016672Cancer Center Support Grant32025
R01AR062173The IL-23/IL-17 Axis in Inflammatory Arthritis32025
R01MH106595Psychiatric Genomics Consortium for PTSD32025
T32ES007015Molecular & Environmental Toxicology Predoctoral Training Program32025
P30CA008748Cancer Center Support Grant22025

1 to 10 of 947Source NIH's project files

See all 947 nih grants

Papers2,683

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Inflammation- and metabolism-related transcriptional features in murine lupus nephritis: A single-cell kidney reanalysis.Transl Oncol202642826657PubTator, text miningPubMed
Efficacy of sequential romosozumab-denosumab therapy in patients on hemodialysis: association with bone mineral density improvement and TRACP-5b rebound.Osteoporos Int202642821093PubTator, text miningPubMed
Combined baseline P1NP and TRAcP5b classification predicts differential bone mineral density response to romosozumab: A retrospective cohort study of 287 postmenopausal women.J Clin Densitom202642809930PubTator, text miningPubMed
Gut Microbiota and SCFA Changes After Alendronate-Calcitriol Therapy in Postmenopausal Osteoporosis.Int J Womens Health202642801217PubTator, text miningPubMed
Equivalent Twelve-Month Bone Mineral Density Response to Romosozumab in Patients Aged ≥ 85 Years and < 85 Years: A Multi-center Real-World Cohort Study (n = 417) from Northern Japan.Calcif Tissue Int202642789080PubTator, text miningPubMed
ACP5-positive macrophages contribute to cerebral oedema and neuroinflammation after traumatic brain injury.Clin Transl Med202642786914PubTator, text miningPubMed
Correlation analysis of serum CCL3, TRACP-5b, and sclerostin with the prognosis of multiple myeloma patients.J Med Biochem202642781632PubTator, text miningPubMed
Correlation analysis of PGC-1β, HIF-1α and RETN with the degree of joint destruction in gouty arthritis.J Med Biochem202642780816PubTator, text miningPubMed
Integrative transcriptomic analysis identifies ACP5 and FBLN5 as candidate shared transcriptomic signatures between pulpitis and carotid plaque rupture.Sci Rep202642744917PubTator, text miningPubMed
Protective effects and mechanisms of puerarin in ovariectomized animal models of osteoporosis: a systematic review and meta-analysis of preclinical studies.Front Physiol202642724066PubTator, text miningPubMed

1 to 10 of 2,683

See all 2,683 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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The record and each of its lists are JSON, twenty rows a page. No key.

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