Gene · 540
ATP7B: ATPase copper transporting beta
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. ATP7B: ATPase copper transporting beta. Genes, record 540. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/540
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| P35670 | Copper-transporting ATPase 2 | 1,465 | 13 | Ensembl, GeneID, HGNC |
Source UniProt
Patents77
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| EP 4754245 A1 | 2026-06-10 | 36 | P35670 | Espacenet |
| JP 2026067851 A | 2026-04-21 | 133 | P35670 | Espacenet |
| JP 2026509434 A | 2026-03-19 | 36 | P35670 | Espacenet |
| EP 4677077 A1 | 2026-01-14 | 36 | P35670 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 1075 | P35670 | Espacenet |
| US 12473567 B2 | 2025-11-18 | 83 | P35670 | Espacenet |
| US 12473568 B2 | 2025-11-18 | 83 | P35670 | Espacenet |
| JP 2025169942 A | 2025-11-14 | 857 | P35670 | Espacenet |
| US 12460228 B2 | 2025-11-04 | 2 | P35670 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 754 | P35670 | Espacenet |
1 to 10 of 77
See all 77 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,162
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | ATP7B papers | Newest fiscal year |
|---|---|---|---|
| R01DK071865 | Molecular Mechanisms of Active Copper Transport | 37 | 2025 |
| R01GM079465 | Chemical Probes to Study Copper Biology | 11 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 10 | 2025 |
| P20GM103395 | Alaska INBRE 5 One Health | 7 | 2025 |
| R35GM118021 | Genetic and Molecular Dissection of the Neurospora Clock | 6 | 2025 |
| R01DK117396 | Copper Homeostasis and Liver Function | 5 | 2025 |
| UL1TR001863 | Yale Clinical and Translational Science Award | 5 | 2025 |
| P30CA013330 | Cancer Center Support Grant | 4 | 2025 |
| P30CA060553 | The Robert H. Lurie Comprehensive Cancer Center | 4 | 2025 |
| P30DK026743 | UCSF Liver Center | 4 | 2025 |
1 to 10 of 1,162Source NIH's project files
See all 1,162 nih grantsPapers3,770
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| A hepatic-targeting NIR fluorescent probe simultaneously unlocked by BChE and high viscosity in diabetes mellitus. | Spectrochim Acta A Mol Biomol Spectrosc | 2027 | 42785018 | PubTator, text mining | PubMed |
| Roles of cuproptosis in central nervous system tumors: from molecular mechanisms to therapeutic prospects. | Front Cell Dev Biol | 2026 | 42812787 | PubTator, text mining | PubMed |
| Disrupted copper homeostasis promotes osteopontin-mediated hepatocyte-stellate cell crosstalk in Wilson disease. | Cytokine | 2026 | 42800295 | PubTator, text mining | PubMed |
| digitalMLPA EZtec-MS: A new highly multiplexed DNA probe-based technique for neonatal screening. | Eur J Hum Genet | 2026 | 42773160 | PubTator, text mining | PubMed |
| Copper homeostasis in macrophages: regulatory mechanisms and immunological implications. | Front Chem | 2026 | 42769650 | PubTator, text mining | PubMed |
| Neutrophil extracellular traps delivering lactylated S100a9 aggravate neuronal cuproptosis by regulating Ttr/Commd1/Atp7b axis after traumatic brain injury. | Redox Biol | 2026 | 42767162 | PubTator, text mining | PubMed |
| SOX2 Inhibits Cuproptosis to Affect Cisplatin Resistance in Non-Small Cell Lung Cancer by Activating the Wnt/ATP7B Signaling Pathway. | Kaohsiung J Med Sci | 2026 | 42757550 | PubTator, text mining | PubMed |
| Utility of High-Throughput Genomic Analysis for Genetic Counseling in Large Family with Wilson Disease Carrying a Novel 28-bp ATP7B Splice-Junction Deletion. | Diagnostics (Basel) | 2026 | 42739114 | PubTator, text mining | PubMed |
| Copper, cuproptosis, and cancer: biology concepts of a novel cell death. | Apoptosis | 2026 | 42693224 | PubTator, text mining | PubMed |
| Diagnostic challenges and mimicking disorders of Wilson's Disease: A comprehensive review. | Caspian J Intern Med | 2026 | 42668699 | PubTator, text mining | PubMed |
1 to 10 of 3,770
See all 3,770 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/540
GET https://conductscience.org/api/genes/v1/540/patents?page=2