ConductScience.org, home

Gene · 5406

PNLIP: pancreatic lipase

12 sourcesgene-search-2026-11-11-0.2.0

Download JSON
Cite this record

ConductScience Library. PNLIP: pancreatic lipase. Genes, record 5406. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/5406

On this page

Gene

Symbol
PNLIP
HGNC
Name
pancreatic lipase
HGNC
NCBI Gene ID
5406
NCBI Gene
HGNC ID
HGNC:9155
HGNC
Ensembl
ENSG00000175535
NCBI Gene
Aliases
PL, PNLIPD, PTL
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P16233Pancreatic triacylglycerol lipase4654Ensembl, GeneID, HGNC

Source UniProt

Patents79

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026094314 A2026-06-0945P16233Espacenet
EP 4705273 A22026-03-11518P16233Espacenet
JP 2026021360 A2026-02-10136P16233Espacenet
JP 2026004568 A2026-01-1457041P16233Espacenet
EP 4650780 A22025-11-198591P16233Espacenet
EP 4641201 A22025-10-298745P16233Espacenet
JP 2025147176 A2025-10-0610576P16233Espacenet
JP 2025529142 A2025-09-047390P16233Espacenet
US 12371689 B22025-07-297390P16233Espacenet
JP 2025517969 A2025-06-128745P16233Espacenet

1 to 10 of 79

See all 79 patents

Drugs2

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource
CETILISTATCHEMBL2103825Pancreatic lipase inhibitorINHIBITORChEMBL
ORLISTATCHEMBL175247Pancreatic lipase inhibitorINHIBITORChEMBL

Trials43

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

NIH grants871

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitlePNLIP papersNewest fiscal year
U01DK108334INSPPIRE: Using the natural history of pediatric chronic pancreatitis to identify disease predictors and design therapies62025
P30CA056036Translational Research in Cancer42025
P30DK052574Host-environment interactions in the pathophysiology of digestive disease32025
P30DK054759Precision Medicine Center for Cystic Fibrosis32025
R01DK128188Pathophysiology of Chronic Pancreatitis Associated with Misfolded PNLIP Risk Variants32025
R01HL086694From GWAS loci to blood pressure genes, variants & mechanisms - Renewal32025
T32GM008562Clinical Pharmacology Training Program32025
U01DK108306UPMC Clinical Center for the Study of Chronic Pancreatitis and Diabetes32025
U01DK108314Cedars Sinai Center for the Chronic Pancreatitis Clinical Research Consortium32025
P01CA125066Discovery of Anticancer Agents of Diverse Natural Origin22025

1 to 10 of 871Source NIH's project files

See all 871 nih grants

Papers3,840

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
A machine learning-assisted colorimetric sensor array based on Fe-doped MnO₂/graphene composites for flavonoid identification and bioactivity prediction in vine tea.Food Chem202642785022PubTator, text miningPubMed
Chemical and Enantioselective Characterization and Preliminary Biological Activities of Aristolochia lingulata Aerial-Part Essential Oil.Plants (Basel)202642739459PubTator, text miningPubMed
Lipase ITB 2.1: a structure- and function-validated model for anti-obesity drug screening.Mol Divers202642732036PubTator, text miningPubMed
Bioactive structural features of natural polysaccharides: Inspiration for novel polymer strategies against metabolic disorders.Carbohydr Res202642715720PubTator, text miningPubMed
A Systematic Review and Meta-Analysis of Malnutrition and Metabolic Failure in High-Potency Incretin Therapy.Obes Sci Pract202642707648PubTator, text miningPubMed
Virtual screening of human pancreatic lipase inhibitors using an integrated transfer learning and molecular dynamics simulation.Bioinformation202642701742PubTator, text miningPubMed
[Two new indole alkaloids from Nelumbinis Folium and their hypolipidemic activities].Zhongguo Zhong Yao Za Zhi202642693050PubTator, text miningPubMed
Antiobesity, antidiabetic, and antioxidant activities of selected Rubia species (Rubiaceae) and LC-MS/MS-based chemical profiling.Turk J Med Sci202642677271PubTator, text miningPubMed
Comparative Characterisation and In Vitro Metabolic Bioactivities of Fucoidan-Rich Extracts from Three South African Brown Macroalgae.Molecules202642653904PubTator, text miningPubMed
Elevated ozone reprograms secondary metabolism in Abelmoschus moschatus pods, enhancing antidiabetic and antiobesity bioactivities.Plant Cell Rep202642622685PubTator, text miningPubMed

1 to 10 of 3,840

See all 3,840 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/5406

GET https://conductscience.org/api/genes/v1/5406/patents?page=2