ConductScience.org, home

Gene · 5409

PNMT: phenylethanolamine N-methyltransferase

12 sourcesgene-search-2026-11-11-0.2.0

Download JSON
Cite this record

ConductScience Library. PNMT: phenylethanolamine N-methyltransferase. Genes, record 5409. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/5409

On this page

Gene

Symbol
PNMT
HGNC
Name
phenylethanolamine N-methyltransferase
HGNC
NCBI Gene ID
5409
NCBI Gene
HGNC ID
HGNC:9160
HGNC
Ensembl
ENSG00000141744
NCBI Gene
Aliases
PENT, PNMTase
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P11086Phenylethanolamine N-methyltransferase28244Ensembl, GeneID, HGNC

Source UniProt

Patents16

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1457552P11086Espacenet
EP 4641201 A22025-10-292305P11086Espacenet
JP 2025517969 A2025-06-122305P11086Espacenet
US 11446398 B22022-09-2062399P11086Espacenet
JP 2022524081 A2022-04-27165370P11086Espacenet
US 11078247 B22021-08-038671P11086Espacenet
JP 2019054813 A2019-04-11237987P11086Espacenet
JP 2017121241 A2017-07-13237987P11086Espacenet
JP 2015516143 A2015-06-08237987P11086Espacenet
EP 2082343 A22009-07-291078P11086Espacenet

1 to 10 of 16

See all 16 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants902

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitlePNMT papersNewest fiscal year
ZIANS003034Biomarkers of Catecholaminergic Neurodegeneration52025
P30CA008748Cancer Center Support Grant42025
ZIAHD001804Regulated expression and developmental functions of the H19 long noncoding RNA42025
ZIAMH002386Chemical Coding of Neurotransmission42025
P30CA016672Cancer Center Support Grant32025
ZIABC011028Clinical Studies of the Molecular Genetic Basis of Kidney Cancer32025
ZIABC011038Molecular Therapeutics of Kidney Cancer: VHL Gene and Fumarate Hydratase Gene32025
ZIDBC011089Clinical Nursing and Data Management Core32025
P30CA021765Cancer Center Support Grant (CCSG)22025
P30CA054174Mays Cancer Center at UT Health SA22025

1 to 10 of 902Source NIH's project files

See all 902 nih grants

Papers2,177

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Differentiation of human embryonic stem cells into adrenal chromaffin-like cells with catecholamine markers, excitability, and Ca2+ signaling.STAR Protoc202642726637PubTator, text miningPubMed
Expression status of neurotrophic tropomyosin receptor kinase (NTRK1) in pheochromocytoma and its association with clinicopathological factors.Histol Histopathol202642145038PubTator, text miningPubMed
A silent pheochromocytoma with regional metastasis and negative germline testing.Endocrinol Diabetes Metab Case Rep202641894836PubTator, text miningPubMed
Subject-specific modeling of response to physical stress via hypothalamic-pituitary-adrenal and sympathoadrenal axes.PLoS One202641875197PubTator, text miningPubMed
[Mendelian Randomization Analysis of Potential Molecular Targets for Type 2 Airway Inflammatory Diseases].Sichuan Da Xue Xue Bao Yi Xue Ban202641834957PubTator, text miningPubMed
Cold exposure and human metabolism: A heterogeneous response across tissues and organs.Temperature (Austin)202641797814PubTator, text miningPubMed
Uncovering Clinically Relevant Breast Cancer Subtypes Biomarkers Using Integrative Bioinformatics and Machine Learning Approaches.Biomarkers202641797509PubTator, text miningPubMed
Epigenetic Landscape of Female Infertility: An Integrated Bioinformatics Perspective on DNA Methylation, MicroRNAs, and Gene Regulatory Networks Across PCOS, Endometriosis, and Diminished Ovarian Reserve.
Int J Mol Sci202641751922PubTator, text miningPubMed
The Burden of Preoperative Stress: Biological Mechanisms and Postoperative Outcomes.Brain Sci202641750219PubTator, text miningPubMed
From Tissue Architecture To Genetic Signature: Artificial intelligence-based Analysis of Reticulin Framework and Clinical Variables Predicts Molecular Cluster in Paragangliomas.Endocr Pathol202641706251PubTator, text miningPubMed

1 to 10 of 2,177

See all 2,177 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/5409

GET https://conductscience.org/api/genes/v1/5409/patents