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POLB: DNA polymerase beta

1 protein, 58 patents, 0 drugs, 0 trials, 2,490 NIH grants and 5,082 papers.

Gene 6

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolPOLBHGNC
NameDNA polymerase betaHGNC
NCBI Gene ID5423NCBI Gene
HGNC IDHGNC:9174HGNC
EnsemblENSG00000070501NCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P06746DNA polymerase beta335435Ensembl, GeneID, HGNCUniProt

Patents 58

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
EP 4780952 A12026-07-2966P06746Espacenet
EP 4688872 A12026-02-1196P06746Espacenet
US 12497601 B22025-12-161163P06746Espacenet
US 12435331 B22025-10-0754P06746Espacenet
US 12415993 B22025-09-161163P06746Espacenet
EP 4551698 A12025-05-1473P06746Espacenet
KR 1020250035540 A2025-03-1273P06746Espacenet
US 12173335 B22024-12-2450P06746Espacenet
JP 2024533316 A2024-09-124429P06746Espacenet
JP 2024123008 A2024-09-107769P06746Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 2490

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P01CA092584Structural Cell Biology of DNA Repair Machines512,025NIH's project files
ZIAES065070Structure-Function Studies Of DNA Replication Fidelity292,025NIH's project files
P30CA047904Cancer Center Support Grant212,025NIH's project files
ZIAAG000726Function of RecQ helicases in genome stability182,025NIH's project files
P30CA016672Cancer Center Support Grant172,025NIH's project files
ZIAAG000723ALZHEIMERS RESEARCH PROJECT: DNA repair dysfunction in neurodegeneration and Alzheimer's Disease172,025NIH's project files
ZIAHD001500DNA Replication, Repair, and Mutagenesis In Eukaryotic And Prokaryotic Cells172,025NIH's project files
ZIALM000073Comparative Analysis Of Completely Sequenced Genomes152,025NIH's project files
P30ES010126UNC Center for Environmental Health and Susceptibility132,025NIH's project files
P30CA006927Comprehensive Cancer Center Program at Fox Chase122,025NIH's project files

Papers 5082

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42649846PubTator, text miningPubMed
42607204PubTator, text miningPubMed
42575091PubTator, text miningPubMed
42574899PubTator, text miningPubMed
42440232PubTator, text miningPubMed
42378620PubTator, text miningPubMed
42227337PubTator, text miningPubMed
41978267Swiss-Prot, curatedPubMed
41928257PubTator, text miningPubMed
41898401PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license