ConductScience.org, home

Library / Genes

PON1: paraoxonase 1

1 protein, 110 patents, 0 drugs, 0 trials, 2,908 NIH grants and 9,117 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolPON1HGNC
Nameparaoxonase 1HGNC
NCBI Gene ID5444NCBI Gene
HGNC IDHGNC:9204HGNC
EnsemblENSG00000005421NCBI Gene
AliasesESA, MVCD5, PONNCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P27169Serum paraoxonase/arylesterase 13551Ensembl, GeneID, HGNCUniProt

Patents 110

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1457080P27169Espacenet
US 12509501 B22025-12-3012P27169Espacenet
US 12497604 B22025-12-164P27169Espacenet
EP 4650780 A22025-11-19554P27169Espacenet
EP 4641201 A22025-10-29391P27169Espacenet
JP 2025147176 A2025-10-0610643P27169Espacenet
JP 2025529142 A2025-09-047403P27169Espacenet
US 12371689 B22025-07-297403P27169Espacenet
JP 2025517969 A2025-06-12391P27169Espacenet
JP 2025517970 A2025-06-12554P27169Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 2908

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30ES007033University of Washington Interdisciplinary Center for Exposures, Diseases, Genomics & Environment472,025NIH's project files
P30DK017047Diabetes Research Center252,025NIH's project files
P30ES009089Center for Environmental Health in Northern Manhattan132,025NIH's project files
P01HL116263HDL Function in Human Disease122,025NIH's project files
P30ES005605Environmental Health Sciences Research Center122,025NIH's project files
P30ES007048Environmental Exposures, Host Factors and Human Disease112,025NIH's project files
P01HL128203Multi-disciplinary Approaches to HDL Structure, Assembly, and Functional Heterogeneity92,025NIH's project files
P30CA006973Regional Oncology Research Center82,025NIH's project files
P30ES019776HERCULES: Exposome Research Center82,025NIH's project files
P30CA036727Buffett Cancer Center Support Grant72,025NIH's project files

Papers 9117

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42797707PubTator, text miningPubMed
42786013PubTator, text miningPubMed
42781334PubTator, text miningPubMed
42778422PubTator, text miningPubMed
42766532PubTator, text miningPubMed
42735825PubTator, text miningPubMed
42726665PubTator, text miningPubMed
42691704PubTator, text miningPubMed
42682961PubTator, text miningPubMed
42653246PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license