Gene · 5449
POU1F1: POU class 1 homeobox 1
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. POU1F1: POU class 1 homeobox 1. Genes, record 5449. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/5449
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| P28069 | Pituitary-specific positive transcription factor 1 | 291 | 1 | Ensembl, GeneID, HGNC |
Source UniProt
Patents29
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 58828 | P28069 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 1822 | P28069 | Espacenet |
| JP 2025147176 A | 2025-10-06 | 15501 | P28069 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 1822 | P28069 | Espacenet |
| JP 2025028160 A | 2025-02-28 | 15501 | P28069 | Espacenet |
| KR 1020250010750 A | 2025-01-21 | 15501 | P28069 | Espacenet |
| JP 2024109657 A | 2024-08-14 | 15340 | P28069 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 65954 | P28069 | Espacenet |
| JP 2022524081 A | 2022-04-27 | 168925 | P28069 | Espacenet |
| JP 2021536249 A | 2021-12-27 | 15694 | P28069 | Espacenet |
1 to 10 of 29
See all 29 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,028
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | POU1F1 papers | Newest fiscal year |
|---|---|---|---|
| R01DK018477 | Enhancer Connectomes in Regulation of Gene Expression | 13 | 2025 |
| T32HL007828 | Cardiovascular Research Training Program | 7 | 2025 |
| P01CA013106 | Targeting Transcription and Splicing in Cancer | 6 | 2025 |
| P30CA046592 | University of Michigan Rogel Cancer Center Support Grant 2023-2028 | 6 | 2025 |
| P30DK019525 | University of Pennsylvania Diabetes Research Center | 5 | 2025 |
| P01CA100730 | Retrovirus Models of Cancer | 4 | 2025 |
| P30CA125123 | Baylor College of Medicine Cancer Center - Cancer Center Support Grant | 4 | 2025 |
| ZIABC010441 | Biomolecular Recognition and Binding Mechanisms | 4 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 3 | 2025 |
| P30CA016056 | Roswell Park Cancer Center Support Grant | 3 | 2025 |
1 to 10 of 1,028Source NIH's project files
See all 1,028 nih grantsPapers2,504
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Deep Learning Based on Magnetic Resonance Imaging for Preoperative Prediction of Pituitary Neuroendocrine Tumors Subtypes. | Acad Radiol | 2026 | 42736093 | PubTator, text mining | PubMed |
| Case Report: Development of a thyrotropinoma in a patient with thyroid hemiagenesis. | Front Endocrinol (Lausanne) | 2026 | 42723820 | PubTator, text mining | PubMed |
| What do you mean by PitNETs in WHO Classification 2022? | Endocr J | 2026 | 42702553 | PubTator, text mining | PubMed |
| Differential expression of cyclin D1 in pituitary neuroendocrine tumours: Relation to aggressive potential. | Afr J Lab Med | 2026 | 42699363 | PubTator, text mining | PubMed |
| Radiomics and artificial intelligence in pituitary adenomas (PitNETs): from imaging biomarkers to clinical translation. | Rev Endocr Metab Disord | 2026 | 42684588 | PubTator, text mining | PubMed |
| Multiparametric MRI-Based Ensemble Deep Learning for Preoperative Classification of Pituitary Neuroendocrine Tumor Subtypes. | Acad Radiol | 2026 | 42680659 | PubTator, text mining | PubMed |
| Cushing disease caused by a TBX19/PIT1 co-expressing pituitary adenoma/pituitary neuroendocrine tumor. | J Neuropathol Exp Neurol | 2026 | 42658565 | PubTator, text mining | PubMed |
Integrin αvβ6 Expression in the Human Pituitary Gland and Pituitary Neuroendocrine Tumors: Immunohistochemical Characterization with Potential Relevance to αvβ6 PET/CT Pituitary Uptake and Theranostic Implications. | Biomolecules | 2026 | 42650848 | PubTator, text mining | PubMed |
| Comparative analysis of SCGN expression patterns in the anterior pituitary gland of mouse, pig, and human by single-cell transcriptomics. | J Neuroendocrinol | 2026 | 42633787 | PubTator, text mining | PubMed |
| Sellar region neurocytomas exhibit a CIMP and neuroendocrine-like epigenetic signature distinct from other intra-axial neurocytomas. | Acta Neuropathol | 2026 | 42611353 | PubTator, text mining | PubMed |
1 to 10 of 2,504
See all 2,504 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/5449
GET https://conductscience.org/api/genes/v1/5449/patents?page=2