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Gene · 5452

POU2F2: POU class 2 homeobox 2

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. POU2F2: POU class 2 homeobox 2. Genes, record 5452. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/5452

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Gene

Symbol
POU2F2
HGNC
Name
POU class 2 homeobox 2
HGNC
NCBI Gene ID
5452
NCBI Gene
HGNC ID
HGNC:9213
HGNC
Ensembl
ENSG00000028277
NCBI Gene
Aliases
OCT2, OTF2, Oct-2
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P09086POU domain, class 2, transcription factor 24792Ensembl, GeneID, HGNC

Source UniProt

Patents20

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1458830P09086Espacenet
EP 4641202 A22025-10-297556P09086Espacenet
JP 2025147176 A2025-10-0615504P09086Espacenet
JP 2025530805 A2025-09-1725P09086Espacenet
KR 1020250068664 A2025-05-1625P09086Espacenet
JP 2025028160 A2025-02-2815504P09086Espacenet
KR 1020250017231 A2025-02-047556P09086Espacenet
KR 1020250010750 A2025-01-2115504P09086Espacenet
JP 2024109657 A2024-08-1415343P09086Espacenet
US 11446398 B22022-09-2065971P09086Espacenet

1 to 10 of 20

See all 20 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,756

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitlePOU2F2 papersNewest fiscal year
ZIASC000550Lymphoma Disease Discovery and Definition222025
ZIABC011070Hematopathology Diagnosis162025
P01CA013106Targeting Transcription and Splicing in Cancer152025
P30CA008748Cancer Center Support Grant122025
P30CA016672Cancer Center Support Grant112025
ZIEBC011241Hematopathology Fellowship102025
P30ES006694Southwest Environmental Health Sciences Center92025
T32CA229102Surgical Oncology Research Training Program62025
ZIABC011354Targeted treatment of B-cell Lymphoma62025
ZIASC006741Therapeutic Strategies and Molecular Correlates in Aggressive B-cell Lymphomas62025

1 to 10 of 1,756Source NIH's project files

See all 1,756 nih grants

Papers3,227

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Metformin Pharmacogenetics in Heart Failure Patients with Reduced Ejection Fraction: Impact on Metformin and Growth Differentiation Factor-15 Plasma Levels.Clin Pharmacokinet202642804152PubTator, text miningPubMed
Structure-guided mapping of ototoxicity-related proteins: drug entry, damage amplification, cell death execution, and endogenous otoprotection.Hear Res202642800300PubTator, text miningPubMed
Clonotypic characterization defines B-cell drivers of clonal expansion and intratumor heterogeneity in IgM monoclonal gammopathies.Hemasphere202642732362PubTator, text miningPubMed
In vitro assessments for pharmacokinetic drug-drug interaction potential of vornorexant, a novel dual orexin 1/2 receptor antagonist.Xenobiotica202642693680PubTator, text miningPubMed
Pediatric Mediastinal Gray Zone Lymphoma With Germline TET2 Heterozygous Variant.Pediatr Blood Cancer202642657693PubTator, text miningPubMed
Berberine-Drug Interactions: Mechanisms, Clinical Relevance and Risk Stratification-A Narrative Review.Pharmaceuticals (Basel)202642653808PubTator, text miningPubMed
Erdheim-Chester Disease with Breast and Axillary Involvement Diagnosed by Ultrasound-Guided Biopsy: A Case Report and Literature Review.J Clin Med202642652736PubTator, text miningPubMed
Extreme PTH-Independent Hypercalcemia Mediated by a Rare Non-Osteoclastic Osteolysis Mechanism in Newly Diagnosed High-Risk Biclonal IgA Multiple Myeloma: Temporal Association with the Second Dose of Moderna mRNA-1273 COVID-19 Vaccine.
Int J Mol Sci202642589488PubTator, text miningPubMed
Optical coherence tomography acquisition efficiency: comparison of Heidelberg spectralis OCT2 module & Zeiss Cirrus HD-OCT model 6000.Front Ophthalmol (Lausanne)202642548476PubTator, text miningPubMed
Distinguishing EBV-positive classic Hodgkin lymphoma from EBV-positive DLBCL, NOS: diagnostic value and limits of immunohistochemical markers.Ann Diagn Pathol202642526361PubTator, text miningPubMed

1 to 10 of 3,227

See all 3,227 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/5452

GET https://conductscience.org/api/genes/v1/5452/patents