Gene · 54578
UGT1A6: UDP glucuronosyltransferase family 1 member A6
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. UGT1A6: UDP glucuronosyltransferase family 1 member A6. Genes, record 54578. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/54578
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| P19224 | UDP-glucuronosyltransferase 1A6 | 532 | 0 | Ensembl, GeneID, HGNC |
Source UniProt
Patents36
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 69122 | P19224 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 4196 | P19224 | Espacenet |
| EP 4640849 A2 | 2025-10-29 | 544 | P19224 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 3750 | P19224 | Espacenet |
| JP 2025529142 A | 2025-09-04 | 5164 | P19224 | Espacenet |
| US 12371689 B2 | 2025-07-29 | 5164 | P19224 | Espacenet |
| JP 2025519096 A | 2025-06-24 | 544 | P19224 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 3750 | P19224 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 4196 | P19224 | Espacenet |
| US 11891360 B2 | 2024-02-06 | 10 | P19224 | Espacenet |
1 to 10 of 36
See all 36 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants963
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | UGT1A6 papers | Newest fiscal year |
|---|---|---|---|
| P30CA021765 | Cancer Center Support Grant (CCSG) | 5 | 2025 |
| ZIABC005708 | Xenobiotic metabolism, cancer chemoprevention and cancer biomarkers | 5 | 2025 |
| P30AI050409 | Center for AIDS Research at Emory University | 3 | 2025 |
| P30CA015704 | Cancer Center Support Grant | 3 | 2025 |
| P30ES005022 | Rutgers Center for Environmental Exposure and Disease (CEED) | 3 | 2025 |
| P42ES016465 | Center for the Science, Technology, and Emerging Health Risks of PAHs | 3 | 2025 |
| R01AA030155 | Inter-Enzyme Crosstalk in the Cytochrome P450 Ensemble: Implications for the Effects of Alcohol on Drug Metabolism and Alcohol-Drug Interactions | 3 | 2025 |
| R01CA080728 | Oncogenic Impact of eIF4E-dependent RNA Export in Cancer | 3 | 2025 |
| R01CA098571 | Molecular Mechanisms of eIF4E Mediated Transformation | 3 | 2025 |
| R01HD081299 | Ontogeny of drug transport | 3 | 2025 |
1 to 10 of 963Source NIH's project files
See all 963 nih grantsPapers1,780
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Identification of vulnerable antimalarial targets using conditional loss of function mutants. | Mol Biochem Parasitol | 2026 | 42570799 | PubTator, text mining | PubMed |
| Differential role for hepatic glucuronidation and sulfonation in controlling the 24S-hydroxycholesterol ability to activate LXR. | Sci Rep | 2026 | 42443275 | PubTator, text mining | PubMed |
| Doxorubicin-induced early-onset chronic progressive cardiotoxicity, pharmacogenetics and survival among breast cancer patients in Zimbabwe. | S Afr Med J | 2026 | 42246857 | PubTator, text mining | PubMed |
| Overlooked aspects of scaling enzyme activity through abundance across tissues and individuals: Insights from kcat measurements in matched liver and intestinal samples. | Drug Metab Dispos | 2026 | 41855594 | PubTator, text mining | PubMed |
| Aster koraiensis Nakai: Insights into Its Phytoconstituents and Pharmacological Properties. | Pharmaceutics | 2026 | 41754924 | PubTator, text mining | PubMed |
| Pterostilbene in the Management and Treatment of Multiple Myeloma. | Curr Issues Mol Biol | 2026 | 41751478 | PubTator, text mining | PubMed |
| Evaluation of Cat Exposure to Bisphenol A (BPA) Using Hair Sample Analysis. | Animals (Basel) | 2026 | 41751028 | PubTator, text mining | PubMed |
| The Effect of Uridine Diphosphate-Glucuronosyltransferase Inhibition on the Pharmacokinetics of Ecopipam and Its Metabolites. | Clin Transl Sci | 2026 | 41693270 | PubTator, text mining | PubMed |
| The Effect of Ecopipam on the Pharmacokinetics of Concomitant Medications. | Clin Transl Sci | 2026 | 41635062 | PubTator, text mining | PubMed |
| Comparative Proteomics of Hepatocytes And Hepatic Cell Lines Using Swath-MS Reveals Significant Variations In Proteins Involved In Energy, Lipid, And Xenobiotic Metabolism. | Curr Drug Metab | 2026 | 41588973 | PubTator, text mining | PubMed |
1 to 10 of 1,780
See all 1,780 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/54578
GET https://conductscience.org/api/genes/v1/54578/patents?page=2