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Gene · 54578

UGT1A6: UDP glucuronosyltransferase family 1 member A6

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. UGT1A6: UDP glucuronosyltransferase family 1 member A6. Genes, record 54578. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/54578

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Gene

Symbol
UGT1A6
HGNC
Name
UDP glucuronosyltransferase family 1 member A6
HGNC
NCBI Gene ID
54578
NCBI Gene
HGNC ID
HGNC:12538
HGNC
Ensembl
ENSG00000167165
NCBI Gene
Aliases
GNT1, HLUGP, HLUGP1, UDPGT 1-6, UGT-1F, UGT1-06, UGT1.6, UGT1A6S, UGT1F
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P19224UDP-glucuronosyltransferase 1A65320Ensembl, GeneID, HGNC

Source UniProt

Patents36

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1469122P19224Espacenet
EP 4650780 A22025-11-194196P19224Espacenet
EP 4640849 A22025-10-29544P19224Espacenet
EP 4641201 A22025-10-293750P19224Espacenet
JP 2025529142 A2025-09-045164P19224Espacenet
US 12371689 B22025-07-295164P19224Espacenet
JP 2025519096 A2025-06-24544P19224Espacenet
JP 2025517969 A2025-06-123750P19224Espacenet
JP 2025517970 A2025-06-124196P19224Espacenet
US 11891360 B22024-02-0610P19224Espacenet

1 to 10 of 36

See all 36 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants963

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleUGT1A6 papersNewest fiscal year
P30CA021765Cancer Center Support Grant (CCSG)52025
ZIABC005708Xenobiotic metabolism, cancer chemoprevention and cancer biomarkers52025
P30AI050409Center for AIDS Research at Emory University32025
P30CA015704Cancer Center Support Grant32025
P30ES005022Rutgers Center for Environmental Exposure and Disease (CEED)32025
P42ES016465Center for the Science, Technology, and Emerging Health Risks of PAHs32025
R01AA030155Inter-Enzyme Crosstalk in the Cytochrome P450 Ensemble: Implications for the Effects of Alcohol on Drug Metabolism and Alcohol-Drug Interactions32025
R01CA080728Oncogenic Impact of eIF4E-dependent RNA Export in Cancer32025
R01CA098571Molecular Mechanisms of eIF4E Mediated Transformation32025
R01HD081299Ontogeny of drug transport32025

1 to 10 of 963Source NIH's project files

See all 963 nih grants

Papers1,780

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Identification of vulnerable antimalarial targets using conditional loss of function mutants.Mol Biochem Parasitol202642570799PubTator, text miningPubMed
Differential role for hepatic glucuronidation and sulfonation in controlling the 24S-hydroxycholesterol ability to activate LXR.Sci Rep202642443275PubTator, text miningPubMed
Doxorubicin-induced early-onset chronic progressive cardiotoxicity, pharmacogenetics and survival among breast cancer patients in Zimbabwe.S Afr Med J202642246857PubTator, text miningPubMed
Overlooked aspects of scaling enzyme activity through abundance across tissues and individuals: Insights from kcat measurements in matched liver and intestinal samples.Drug Metab Dispos202641855594PubTator, text miningPubMed
Aster koraiensis Nakai: Insights into Its Phytoconstituents and Pharmacological Properties.Pharmaceutics202641754924PubTator, text miningPubMed
Pterostilbene in the Management and Treatment of Multiple Myeloma.Curr Issues Mol Biol202641751478PubTator, text miningPubMed
Evaluation of Cat Exposure to Bisphenol A (BPA) Using Hair Sample Analysis.Animals (Basel)202641751028PubTator, text miningPubMed
The Effect of Uridine Diphosphate-Glucuronosyltransferase Inhibition on the Pharmacokinetics of Ecopipam and Its Metabolites.Clin Transl Sci202641693270PubTator, text miningPubMed
The Effect of Ecopipam on the Pharmacokinetics of Concomitant Medications.Clin Transl Sci202641635062PubTator, text miningPubMed
Comparative Proteomics of Hepatocytes And Hepatic Cell Lines Using Swath-MS Reveals Significant Variations In Proteins Involved In Energy, Lipid, And Xenobiotic Metabolism.Curr Drug Metab202641588973PubTator, text miningPubMed

1 to 10 of 1,780

See all 1,780 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

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The record and each of its lists are JSON, twenty rows a page. No key.

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