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EGLN1: egl-9 family hypoxia inducible factor 1
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Gene · 54583

Papers3,727

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

21 to 40 of 3,727

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TitleJournalYearPMIDFound bySource
Comprehensive analysis of HB-PHD transcription factors associated with drought and salt stresses in wheat.BMC Genomics202642271227PubTator, text miningPubMed
Plasma proteomics improves risk prediction in heart failure and reveals unique biology in chronic chagas cardiomyopathy.PLoS Negl Trop Dis202642258512PubTator, text miningPubMed
HIF-1α Signaling in Uterine Fibroids: A Central Integrator of Hypoxic, Hormonal, and Fibrotic Pathways.Oxygen (Basel)202642181792PubTator, text miningPubMed
Combinatorial histone modifications direct ATP-dependent chromatin remodeling by NURF to promoter-proximal nucleosomes.Nucleic Acids Res202642165139PubTator, text miningPubMed
P53 - a new player in the metabolic adaptation of colorectal carcinoma cells under hypoxia.BMC Cancer202642157167PubTator, text miningPubMed
Pharmacologic activation of PHD2 sensitizes non-small cell lung cancer cells to osimertinib.Biomed Pharmacother202642134241PubTator, text miningPubMed
HCMV infection depends on EGLN1-mediated mitochondrial activation to increase dNTP pools for viral DNA replication.Cell Rep202642060462PubTator, text miningPubMed
Hypoxic CA9 variant as a potential prognostic marker in gastric and breast cancers.Sci Rep202642032036PubTator, text miningPubMed
Mechanistic Insights into Dioxygen Transport Routes in the PHD2 Oxygenase from Long-Time Scale Simulations.Biochemistry202642023757PubTator, text miningPubMed
[Hereditary erythrocytosis caused by a novel EGLN1 gene mutation: a case report].Zhonghua Xue Ye Xue Za Zhi202641991319PubTator, text miningPubMed
Epigenetic dichotomy in florid vs. gliotic proliferative diabetic retinopathy: hypomethylation of EGLN1 and MMP9 drives divergent pathogenic pathways in angiogenesis and fibrosis.Front Endocrinol (Lausanne)202641958874PubTator, text miningPubMed
High-impact Genetic Variants in EGLN1, EPAS1, and Other Genes Identified in Mountaineers by Exome Sequencing.Front Biosci (Schol Ed)202641914177PubTator, text miningPubMed
Distinct metabolomic and proteomic signatures in Parkinson's disease patients with REM sleep behavior disorder.Signal Transduct Target Ther202641912482PubTator, text miningPubMed
Reactive oxygen species (ROS) in cancer: from mechanism to therapeutic implications.Signal Transduct Target Ther202641881983PubTator, text miningPubMed
Noncanonical role of KDM5C in conferring bortezomib resistance via the PERK‒Nrf2 axis in multiple myeloma.Cell Death Dis202641872155PubTator, text miningPubMed
Interleukin 11-Induced MicroRNAs as Functional Mediators and Circulating Biomarkers of Cardiac Fibrosis.Circ Res202641841256PubTator, text miningPubMed
LDH isozymes as targets for cancer therapy.J Enzyme Inhib Med Chem202641837490PubTator, text miningPubMed
Genetic Variants Associated with Persistent Pulmonary Hypertension of Newborn: A Systematic Review.Neonatology202641824641PubTator, text miningPubMed
Identification of an emerging heterozygous variant in KAT6A by whole exome sequencing: a case report.Transl Pediatr202641810193PubTator, text miningPubMed
Bilateral pheochromocytoma: case series and review of treatment strategies based on genetic mutations.Transl Androl Urol202641809780PubTator, text miningPubMed

gene-search-2026-11-11-0.2.0

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Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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