ConductScience.org, home

Library / Genes

POU5F1: POU class 5 homeobox 1

1 protein, 415 patents, 0 drugs, 0 trials, 11,423 NIH grants and 31,047 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolPOU5F1HGNC
NamePOU class 5 homeobox 1HGNC
NCBI Gene ID5460NCBI Gene
HGNC IDHGNC:9221HGNC
EnsemblENSG00000204531NCBI Gene
AliasesMGC22487, OCT-4, OCT3, OCT4, OCT4Borf1, OTF-3, OTF3, OTF4, Oct-3, Oct-4, Oct3/4, Oct4NCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
Q01860POU domain, class 5, transcription factor 136016Ensembl, GeneID, HGNCUniProt

Patents 415

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
EP 4810598 A22026-09-2310Q01860Espacenet
EP 4805378 A12026-09-16613Q01860Espacenet
EP 4805378 A12026-09-16721Q01860Espacenet
WO 2026171881 A12026-08-201Q01860Espacenet
EP 4759932 A12026-06-171Q01860Espacenet
JP 2026091847 A2026-06-041Q01860Espacenet
EP 4733399 A12026-04-292Q01860Espacenet
EP 4705273 A22026-03-118Q01860Espacenet
US 12559772 B22026-02-241Q01860Espacenet
WO 2026024954 A22026-01-2952Q01860Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 11423

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA008748Cancer Center Support Grant1352,025NIH's project files
P30CA016672Cancer Center Support Grant862,025NIH's project files
R01HL113006Human Induced Pluripotent Stem Cells for Cardiovascular Disease Modeling342,025NIH's project files
P30CA014195Cancer Center Support Grant (CCSG)322,025NIH's project files
ZICHL006145NHLBI iPSC Core Facility282,025NIH's project files
P30CA016086Cancer Center Support Grant262,025NIH's project files
P30CA036727Buffett Cancer Center Support Grant262,025NIH's project files
ZIATR000018Drug Repurposing Screening for Rare and Neglected Diseases262,025NIH's project files
R01HL130020Elucidating Mechanism of Cardiac Fibrosis with Cell Village of Pooled Human iPSCs252,025NIH's project files
P30CA060553The Robert H. Lurie Comprehensive Cancer Center242,025NIH's project files

Papers 31047

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42822446PubTator, text miningPubMed
42797937PubTator, text miningPubMed
42780575PubTator, text miningPubMed
42774993PubTator, text miningPubMed
42760772PubTator, text miningPubMed
42759051PubTator, text miningPubMed
42744918PubTator, text miningPubMed
42738506PubTator, text miningPubMed
42738367PubTator, text miningPubMed
42734761PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license