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PPARD: peroxisome proliferator activated receptor delta

1 protein, 99 patents, 14 drugs, 65 trials, 3,433 NIH grants and 7,189 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolPPARDHGNC
Nameperoxisome proliferator activated receptor deltaHGNC
NCBI Gene ID5467NCBI Gene
HGNC IDHGNC:9235HGNC
EnsemblENSG00000112033NCBI Gene
AliasesFAAR, NR1C2, NUC1, NUCI, NUCII, PPARBNCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
Q03181Peroxisome proliferator-activated receptor delta44156Ensembl, GeneID, HGNCUniProt

Patents 99

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
JP 2026086503 A2026-05-2681Q03181Espacenet
JP 2026004568 A2026-01-1457459Q03181Espacenet
JP 2026004568 A2026-01-1457461Q03181Espacenet
EP 4641201 A22025-10-294291Q03181Espacenet
JP 2025147176 A2025-10-0615519Q03181Espacenet
JP 2025517969 A2025-06-124291Q03181Espacenet
US 12268672 B22025-04-081Q03181Espacenet
EP 4516308 A22025-03-0581Q03181Espacenet
JP 2025028160 A2025-02-2815519Q03181Espacenet
KR 1020250010750 A2025-01-2115519Q03181Espacenet

Drugs 14

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource
AVE0847CHEMBL3545295Peroxisome proliferator-activated receptor delta agonistAGONISTChEMBL
BEZAFIBRATECHEMBL264374Peroxisome proliferator-activated receptor agonistAGONISTChEMBL
CER-002CHEMBL3544958Peroxisome proliferator-activated receptor delta agonistAGONISTChEMBL
CHIGLITAZARCHEMBL4650349Peroxisome proliferator-activated receptor agonistAGONISTChEMBL
DB959CHEMBL3545176Peroxisome proliferator-activated receptor delta agonistAGONISTChEMBL
ELAFIBRANORCHEMBL3707395Peroxisome proliferator-activated receptor delta agonistAGONISTChEMBL
FONADELPARCHEMBL3545186Peroxisome proliferator-activated receptor delta agonistAGONISTChEMBL
GW501516CHEMBL38943Peroxisome proliferator-activated receptor delta agonistAGONISTChEMBL
INDEGLITAZARCHEMBL1232583Peroxisome proliferator-activated receptor agonistAGONISTChEMBL
KD3010CHEMBL3545114Peroxisome proliferator-activated receptor delta agonistAGONISTChEMBL

Trials 65

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource
NCT07580638CHIGLITAZARClinicalTrials.gov
NCT07387549ELAFIBRANORPHASE3ClinicalTrials.gov
NCT07303803CHIGLITAZARPHASE2ClinicalTrials.gov
NCT06964230DB959PHASE2/PHASE3ClinicalTrials.gov
NCT06773221CHIGLITAZARClinicalTrials.gov
NCT06730061ELAFIBRANORPHASE3ClinicalTrials.gov
NCT06488911BEZAFIBRATEPHASE3ClinicalTrials.gov
NCT06443606BEZAFIBRATEPHASE3ClinicalTrials.gov
NCT06383403ELAFIBRANORPHASE3ClinicalTrials.gov
NCT06125587CHIGLITAZARPHASE2/PHASE3ClinicalTrials.gov

NIH grants 3433

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
ZIABC005708Xenobiotic metabolism, cancer chemoprevention and cancer biomarkers412,025NIH's project files
P30CA016672Cancer Center Support Grant282,025NIH's project files
ZIABC005562Xenobiotic receptors282,025NIH's project files
P30CA014195Cancer Center Support Grant (CCSG)152,025NIH's project files
P30DK056341Washington University Nutrition Obesity Research Center152,025NIH's project files
P50AA011999Southern California Research Center for ALPD and Cirrhosis102,025NIH's project files
P30CA068485Cancer Center Support Grant92,025NIH's project files
R01AA011431FASD Inhibition of ASPH-Notch Mediates Adolescent Cerebral White Matter Pathology-Potential Utility of Non-invasive Extracellular Vesicle Assays92,025NIH's project files
P30DK056350Nutrition Obesity Research Center (NORC)82,025NIH's project files
P30DK072476Pennington/Louisiana NORC82,025NIH's project files

Papers 7189

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42825974PubTator, text miningPubMed
42798953PubTator, text miningPubMed
42795351PubTator, text miningPubMed
42788381PubTator, text miningPubMed
42769337PubTator, text miningPubMed
42768738PubTator, text miningPubMed
42758314PubTator, text miningPubMed
42757476PubTator, text miningPubMed
42690469PubTator, text miningPubMed
42643821PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license