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PPARG: peroxisome proliferator activated receptor gamma

1 protein, 119 patents, 40 drugs, 721 trials, 17,382 NIH grants and 57,202 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolPPARGHGNC
Nameperoxisome proliferator activated receptor gammaHGNC
NCBI Gene ID5468NCBI Gene
HGNC IDHGNC:9236HGNC
EnsemblENSG00000132170NCBI Gene
AliasesCIMT1, FPLD3, GLM1, NR1C3, PPARG1, PPARG2, PPARG5, PPARgammaNCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P37231Peroxisome proliferator-activated receptor gamma505380Ensembl, GeneID, HGNCUniProt

Patents 119

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
EP 4805378 A12026-09-16663P37231Espacenet
JP 2026086503 A2026-05-2675P37231Espacenet
JP 2026509481 A2026-03-1910P37231Espacenet
EP 4705462 A22026-03-11124P37231Espacenet
JP 2026004568 A2026-01-1457466P37231Espacenet
KR 1020250164239 A2025-11-2410P37231Espacenet
EP 4640849 A22025-10-29410P37231Espacenet
EP 4641201 A22025-10-292910P37231Espacenet
JP 2025157475 A2025-10-1557P37231Espacenet
JP 2025147176 A2025-10-0615520P37231Espacenet

Drugs 40

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource
ALEGLITAZARCHEMBL519504Peroxisome proliferator-activated receptor gamma agonistAGONISTChEMBL
ARHALOFENATECHEMBL2103824Peroxisome proliferator-activated receptor gamma modulatorMODULATORChEMBL
ATX08-001CHEMBL3545278Peroxisome proliferator-activated receptor gamma modulatorMODULATORChEMBL
AVE0847CHEMBL3545295Peroxisome proliferator-activated receptor gamma agonistAGONISTChEMBL
BALAGLITAZONECHEMBL2103991Peroxisome proliferator-activated receptor gamma partial agonistPARTIAL AGONISTChEMBL
BALSALAZIDECHEMBL1201346Peroxisome proliferator-activated receptor gamma agonistAGONISTChEMBL
BALSALAZIDE DISODIUMCHEMBL1200760Peroxisome proliferator-activated receptor gamma agonistAGONISTChEMBL
BARDOXOLONE METHYLCHEMBL1762621Peroxisome proliferator-activated receptor gamma antagonistANTAGONISTChEMBL
BEZAFIBRATECHEMBL264374Peroxisome proliferator-activated receptor agonistAGONISTChEMBL
CHIGLITAZARCHEMBL4650349Peroxisome proliferator-activated receptor agonistAGONISTChEMBL

Trials 721

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource
NCT07604779PIOGLITAZONEClinicalTrials.gov
NCT07580638CHIGLITAZARClinicalTrials.gov
NCT07472179PIOGLITAZONEClinicalTrials.gov
NCT07424677SAROGLITAZARPHASE3ClinicalTrials.gov
NCT07389824MESALAMINEClinicalTrials.gov
NCT07333716MESALAMINEPHASE2ClinicalTrials.gov
NCT07303803CHIGLITAZARPHASE2ClinicalTrials.gov
NCT07289750PIOGLITAZONEPHASE4ClinicalTrials.gov
NCT07248644MESALAMINEPHASE4ClinicalTrials.gov
NCT07216235SAROGLITAZARPHASE3ClinicalTrials.gov

NIH grants 17382

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30DK020572Michigan Diabetes Research Center (MDRC)1132,025NIH's project files
P30CA016672Cancer Center Support Grant1092,025NIH's project files
P30DK056341Washington University Nutrition Obesity Research Center832,025NIH's project files
P30DK063491Diabetes Research Center (DRC)762,025NIH's project files
P30CA008748Cancer Center Support Grant752,025NIH's project files
P30DK072476Pennington/Louisiana NORC612,025NIH's project files
P30DK036836Diabetes Research Center542,025NIH's project files
P30DK020579Diabetes Research Center532,025NIH's project files
R01DK049780Nuclear Receptors in Metabolic Tissues482,025NIH's project files
P30DK019525University of Pennsylvania Diabetes Research Center452,025NIH's project files

Papers 57202

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42826791PubTator, text miningPubMed
42819837PubTator, text miningPubMed
42814403PubTator, text miningPubMed
42813828PubTator, text miningPubMed
42813704PubTator, text miningPubMed
42812065PubTator, text miningPubMed
42811535PubTator, text miningPubMed
42809160PubTator, text miningPubMed
42807712PubTator, text miningPubMed
42806342PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license