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PDP1: pyruvate dehydrogenase phosphatase catalytic subunit 1

1 protein, 39 patents, 0 drugs, 0 trials, 3,293 NIH grants and 5,522 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolPDP1HGNC
Namepyruvate dehydrogenase phosphatase catalytic subunit 1HGNC
NCBI Gene ID54704NCBI Gene
HGNC IDHGNC:9279HGNC
EnsemblENSG00000164951NCBI Gene
AliasesPDH, PDP, PDPC, PDPC 1, PPM2A, PPM2CNCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
Q9P0J1[Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 1, mitochondrial5370Ensembl, GeneID, HGNCUniProt

Patents 39

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
JP 2026067851 A2026-04-21376Q9P0J1Espacenet
JP 2026004568 A2026-01-1460575Q9P0J1Espacenet
JP 2026004568 A2026-01-1460577Q9P0J1Espacenet
JP 2026004568 A2026-01-1460582Q9P0J1Espacenet
EP 4641201 A22025-10-293402Q9P0J1Espacenet
JP 2025517969 A2025-06-123402Q9P0J1Espacenet
JP 2023521663 A2023-05-25375Q9P0J1Espacenet
US 11446398 B22022-09-2070351Q9P0J1Espacenet
US 11446398 B22022-09-2070353Q9P0J1Espacenet
US 11446398 B22022-09-2070357Q9P0J1Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 3293

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA008748Cancer Center Support Grant212,025NIH's project files
P30CA177558University of Kentucky Markey Cancer Center – Cancer Center Support Grant202,025NIH's project files
P30CA016672Cancer Center Support Grant182,025NIH's project files
P41EB013598Hyperpolarized MRI Technology Resource Center142,025NIH's project files
P01AG026572Perimenopause in Brain Aging and Alzheimer's Disease122,025NIH's project files
ZIABC011038Molecular Therapeutics of Kidney Cancer: VHL Gene and Fumarate Hydratase Gene122,025NIH's project files
R35CA220449Human metabolic variation as a window into cancer initiation and progression112,025NIH's project files
ZIABC011028Clinical Studies of the Molecular Genetic Basis of Kidney Cancer112,025NIH's project files
P20GM121327University of Kentucky Center for Cancer Metabolism102,025NIH's project files
P30CA010815Consolidated Basic Cancer Research Program92,025NIH's project files

Papers 5522

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42806865PubTator, text miningPubMed
42782835PubTator, text miningPubMed
42752765PubTator, text miningPubMed
42641775PubTator, text miningPubMed
42615326PubTator, text miningPubMed
42574799PubTator, text miningPubMed
42565227PubTator, text miningPubMed
42549036PubTator, text miningPubMed
42533112PubTator, text miningPubMed
42491861PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license