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Gene · 5476

CTSA: cathepsin A

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. CTSA: cathepsin A. Genes, record 5476. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/5476

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Gene

Symbol
CTSA
HGNC
Name
cathepsin A
HGNC
NCBI Gene ID
5476
NCBI Gene
HGNC ID
HGNC:9251
HGNC
Ensembl
ENSG00000064601
NCBI Gene
Aliases
BSVD6, GLB2, GSL, NGBE, PPCA, PPGB
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P10619Lysosomal protective protein48012Ensembl, GeneID, HGNC

Source UniProt

Patents66

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026067851 A2026-04-21262P10619Espacenet
US 12539325 B22026-02-0332P10619Espacenet
JP 2026004568 A2026-01-1440316P10619Espacenet
EP 4650780 A22025-11-19177P10619Espacenet
JP 2025147176 A2025-10-063693P10619Espacenet
JP 2025147176 A2025-10-063694P10619Espacenet
JP 2025147176 A2025-10-063695P10619Espacenet
JP 2025529142 A2025-09-046052P10619Espacenet
US 12371689 B22025-07-296052P10619Espacenet
JP 2025517970 A2025-06-12177P10619Espacenet

1 to 10 of 66

See all 66 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,480

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleCTSA papersNewest fiscal year
P30CA021765Cancer Center Support Grant (CCSG)132025
P30AI050409Center for AIDS Research at Emory University62025
P30CA016672Cancer Center Support Grant62025
P30AI050410The University of North Carolina Center for AIDS Research42025
P30CA138313Medical University of South Carolina - Cancer Center Support Grant42025
UL1TR001863Yale Clinical and Translational Science Award42025
P20GM103442ND INBRE Health & the Environment32025
P30AI027763UCSF-Bay Area Center for AIDS Research32025
P30CA008748Cancer Center Support Grant32025
P30CA068485Cancer Center Support Grant32025

1 to 10 of 1,480Source NIH's project files

See all 1,480 nih grants

Papers2,520

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Glucosylceramide synthase is required for C6-ceramide nanoliposome-induced organelle stress and cell death.bioRxiv202642818015PubTator, text miningPubMed
Exogenous Methyl Jasmonate Promotes Glucosinolate Accumulation and Antioxidant Capacity in Kale Sprouts.Physiol Plant202642683673PubTator, text miningPubMed
A clinically derived lipid-endothelial signature links serum multi-omics to immune exclusion and clinical stratification in hepatocellular carcinoma.Ther Adv Med Oncol202642682961PubTator, text miningPubMed
Molecular mechanisms of chronic dietary cholesterol-driven remodeling of LDLR protein fate.Yi Chuan202642608182PubTator, text miningPubMed
Proteome-Level Autophagy-Lysosome Remodelling Marks Ageing in Human Dermal Fibroblasts and Nominates Hydroxytyrosol as a Candidate Nutraceutical.Int J Mol Sci202642589464PubTator, text miningPubMed
Evaluation of Antisense Oligonucleotide-Associated Neuronal Lysosomal Changes.Nucleic Acid Ther202642560023PubTator, text miningPubMed
The multifaceted role of cathepsin a in glioblastoma pathogenesis: from molecular scaffolding to immunological evasion.Cell Signal202642526700PubTator, text miningPubMed
Backbone N-Methylation Improves PPCA-Binding of a Stylissatin A Analogue via Conformational Modulation.Chem Asian J202642502249PubTator, text miningPubMed
Ensemble Machine Learning Approaches Predict Survival in Lower-Grade Glioma Based on Glycosphingolipid Gene Expression and Metabolic Modeling.Comput Struct Biotechnol J202642368494PubTator, text miningPubMed
Dietary cholesterol activates a Ral-dependent pathway driving LDLR turnover.Nature202642343138PubTator, text miningPubMed

1 to 10 of 2,520

See all 2,520 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/5476

GET https://conductscience.org/api/genes/v1/5476/patents?page=2