Gene · 5476
CTSA: cathepsin A
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. CTSA: cathepsin A. Genes, record 5476. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/5476
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| P10619 | Lysosomal protective protein | 480 | 12 | Ensembl, GeneID, HGNC |
Source UniProt
Patents66
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026067851 A | 2026-04-21 | 262 | P10619 | Espacenet |
| US 12539325 B2 | 2026-02-03 | 32 | P10619 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 40316 | P10619 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 177 | P10619 | Espacenet |
| JP 2025147176 A | 2025-10-06 | 3693 | P10619 | Espacenet |
| JP 2025147176 A | 2025-10-06 | 3694 | P10619 | Espacenet |
| JP 2025147176 A | 2025-10-06 | 3695 | P10619 | Espacenet |
| JP 2025529142 A | 2025-09-04 | 6052 | P10619 | Espacenet |
| US 12371689 B2 | 2025-07-29 | 6052 | P10619 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 177 | P10619 | Espacenet |
1 to 10 of 66
See all 66 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,480
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | CTSA papers | Newest fiscal year |
|---|---|---|---|
| P30CA021765 | Cancer Center Support Grant (CCSG) | 13 | 2025 |
| P30AI050409 | Center for AIDS Research at Emory University | 6 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 6 | 2025 |
| P30AI050410 | The University of North Carolina Center for AIDS Research | 4 | 2025 |
| P30CA138313 | Medical University of South Carolina - Cancer Center Support Grant | 4 | 2025 |
| UL1TR001863 | Yale Clinical and Translational Science Award | 4 | 2025 |
| P20GM103442 | ND INBRE Health & the Environment | 3 | 2025 |
| P30AI027763 | UCSF-Bay Area Center for AIDS Research | 3 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 3 | 2025 |
| P30CA068485 | Cancer Center Support Grant | 3 | 2025 |
1 to 10 of 1,480Source NIH's project files
See all 1,480 nih grantsPapers2,520
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Glucosylceramide synthase is required for C6-ceramide nanoliposome-induced organelle stress and cell death. | bioRxiv | 2026 | 42818015 | PubTator, text mining | PubMed |
| Exogenous Methyl Jasmonate Promotes Glucosinolate Accumulation and Antioxidant Capacity in Kale Sprouts. | Physiol Plant | 2026 | 42683673 | PubTator, text mining | PubMed |
| A clinically derived lipid-endothelial signature links serum multi-omics to immune exclusion and clinical stratification in hepatocellular carcinoma. | Ther Adv Med Oncol | 2026 | 42682961 | PubTator, text mining | PubMed |
| Molecular mechanisms of chronic dietary cholesterol-driven remodeling of LDLR protein fate. | Yi Chuan | 2026 | 42608182 | PubTator, text mining | PubMed |
| Proteome-Level Autophagy-Lysosome Remodelling Marks Ageing in Human Dermal Fibroblasts and Nominates Hydroxytyrosol as a Candidate Nutraceutical. | Int J Mol Sci | 2026 | 42589464 | PubTator, text mining | PubMed |
| Evaluation of Antisense Oligonucleotide-Associated Neuronal Lysosomal Changes. | Nucleic Acid Ther | 2026 | 42560023 | PubTator, text mining | PubMed |
| The multifaceted role of cathepsin a in glioblastoma pathogenesis: from molecular scaffolding to immunological evasion. | Cell Signal | 2026 | 42526700 | PubTator, text mining | PubMed |
| Backbone N-Methylation Improves PPCA-Binding of a Stylissatin A Analogue via Conformational Modulation. | Chem Asian J | 2026 | 42502249 | PubTator, text mining | PubMed |
| Ensemble Machine Learning Approaches Predict Survival in Lower-Grade Glioma Based on Glycosphingolipid Gene Expression and Metabolic Modeling. | Comput Struct Biotechnol J | 2026 | 42368494 | PubTator, text mining | PubMed |
| Dietary cholesterol activates a Ral-dependent pathway driving LDLR turnover. | Nature | 2026 | 42343138 | PubTator, text mining | PubMed |
1 to 10 of 2,520
See all 2,520 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/5476
GET https://conductscience.org/api/genes/v1/5476/patents?page=2