Gene · 5479
PPIB: peptidylprolyl isomerase B
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. PPIB: peptidylprolyl isomerase B. Genes, record 5479. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/5479
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| P23284 | Peptidyl-prolyl cis-trans isomerase B | 216 | 8 | Ensembl, GeneID, HGNC |
Source UniProt
Patents101
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| US 12624353 B2 | 2026-05-12 | 493 | P23284 | Espacenet |
| US 12624354 B2 | 2026-05-12 | 493 | P23284 | Espacenet |
| JP 2026062659 A | 2026-04-10 | 493 | P23284 | Espacenet |
| US 12570972 B2 | 2026-03-10 | 493 | P23284 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 57314 | P23284 | Espacenet |
| US 12509680 B2 | 2025-12-30 | 493 | P23284 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 3974 | P23284 | Espacenet |
| JP 2025147176 A | 2025-10-06 | 10671 | P23284 | Espacenet |
| JP 2025529142 A | 2025-09-04 | 7408 | P23284 | Espacenet |
| US 12371689 B2 | 2025-07-29 | 7408 | P23284 | Espacenet |
1 to 10 of 101
See all 101 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,634
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | PPIB papers | Newest fiscal year |
|---|---|---|---|
| P30CA008748 | Cancer Center Support Grant | 13 | 2025 |
| ZIAHD000256 | Collagen-related diseases | 8 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 6 | 2025 |
| P30CA046592 | University of Michigan Rogel Cancer Center Support Grant 2023-2028 | 5 | 2025 |
| P30CA142543 | UT Southwestern Medical Center Simmons Comprehensive Cancer Center | 5 | 2025 |
| P30DK020572 | Michigan Diabetes Research Center (MDRC) | 5 | 2025 |
| P30CA006927 | Comprehensive Cancer Center Program at Fox Chase | 4 | 2025 |
| P30CA068485 | Cancer Center Support Grant | 4 | 2025 |
| P30CA125123 | Baylor College of Medicine Cancer Center - Cancer Center Support Grant | 4 | 2025 |
| R35GM119840 | Chemical biology approaches to probe signaling by protein lipidation | 4 | 2025 |
1 to 10 of 1,634Source NIH's project files
See all 1,634 nih grantsPapers2,141
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| PPIB and its role in prostate cancer: associations with transcriptomic and splicing alterations. | Front Oncol | 2026 | 42774112 | PubTator, text mining | PubMed |
| Correction: PPIB interacts with MET to activate the PI3K-AKT pathway and promote head and neck squamous cell carcinoma pathogenesis. | Mol Biol Rep | 2026 | 42714721 | PubTator, text mining | PubMed |
| Prognostic Significance and Functional Role of PPIB in a Retrospective Cohort of Patients with Advanced Gastric Cancer. | Oncol Res | 2026 | 42630697 | PubTator, text mining | PubMed |
| PPIB interacts with MET to activate the PI3K-AKT pathway and promote head and neck squamous cell carcinoma pathogenesis. | Mol Biol Rep | 2026 | 42611118 | PubTator, text mining | PubMed |
| Multimodal Single-Cell Network Analysis Identifies Basigin/Cluster of Differentiation 147 as a Tumor-Associated Signaling Hub in Hepatocellular Carcinoma. | Gastro Hep Adv | 2026 | 42598059 | PubTator, text mining | PubMed |
| Proteomic Differentiation of Colorectal Cancer From Normal Tissue via Ex Vivo E-Biopsy: A Novel Approach to Molecular Sampling for Diagnostic Precision. | Cancer Med | 2026 | 42576270 | PubTator, text mining | PubMed |
| Peptidyl-prolyl isomerase B suppresses BEFV- and VSV-induced type I interferon responses via degradation of PBLD. | Vet Microbiol | 2026 | 42456219 | PubTator, text mining | PubMed |
| Biotransformation mechanisms of polycyclic aromatic hydrocarbons by Raphidocelis subcapitata: The role of cytochrome P450. | Ecotoxicol Environ Saf | 2026 | 42391845 | PubTator, text mining | PubMed |
| A Novel CAF-Related Signature for Precise Prediction of Clinical Outcomes and Immunotherapy Response for Breast Cancer Patients: Based on Multiomics Analyses and Experimental Validation. | Mediators Inflamm | 2026 | 42359574 | PubTator, text mining | PubMed |
| Cross-Platform Comparative Spatial Transcriptomics in High-Grade Serous Carcinoma. | Lab Invest | 2026 | 42142589 | PubTator, text mining | PubMed |
1 to 10 of 2,141
See all 2,141 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/5479
GET https://conductscience.org/api/genes/v1/5479/patents?page=2