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TET2: tet methylcytosine dioxygenase 2

1 protein, 107 patents, 0 drugs, 0 trials, 5,333 NIH grants and 11,361 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolTET2HGNC
Nametet methylcytosine dioxygenase 2HGNC
NCBI Gene ID54790NCBI Gene
HGNC IDHGNC:25941HGNC
EnsemblENSG00000168769NCBI Gene
AliasesFLJ20032, IMD75, KIAA1546, MDSNCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
Q6N021Methylcytosine dioxygenase TET22,0026Ensembl, GeneID, HGNCUniProt

Patents 107

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
JP 2026515013 A2026-05-1312Q6N021Espacenet
WO 2025254779 A12025-12-112Q6N021Espacenet
US 12467082 B22025-11-1128Q6N021Espacenet
EP 4640849 A22025-10-291546Q6N021Espacenet
EP 4641201 A22025-10-2910560Q6N021Espacenet
JP 2025147176 A2025-10-0615749Q6N021Espacenet
JP 2025147176 A2025-10-0616603Q6N021Espacenet
JP 2025519096 A2025-06-241546Q6N021Espacenet
US 12338489 B22025-06-2428Q6N021Espacenet
US 12331346 B22025-06-1728Q6N021Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 5333

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA008748Cancer Center Support Grant2132,025NIH's project files
P30CA016672Cancer Center Support Grant1882,025NIH's project files
P30CA016058Cancer Center Support Grant412,025NIH's project files
R01HL148565Clonal Hematopoiesis in the Women's Health Initiative322,025NIH's project files
P01CA066996Development of Novel Therapeutic Strategies in Human Leukemias312,025NIH's project files
P30CA006973Regional Oncology Research Center312,025NIH's project files
P01CA108671Myeloproliferative Neoplasms-Research Consortium292,025NIH's project files
U10CA180821Alliance for Clinical Trials in Oncology Operations Center - GY11 Funded Extension272,025NIH's project files
P30CA076292Moffitt Cancer Center Support Grant262,025NIH's project files
P30CA015083Mayo Clinic Comprehensive Cancer Center Support Grant252,025NIH's project files

Papers 11361

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42821569PubTator, text miningPubMed
42821551PubTator, text miningPubMed
42812562PubTator, text miningPubMed
42809396PubTator, text miningPubMed
42807682PubTator, text miningPubMed
42806052PubTator, text miningPubMed
42796004PubTator, text miningPubMed
42794438PubTator, text miningPubMed
42781284PubTator, text miningPubMed
42779366PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license