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TRPM4: transient receptor potential cation channel subfamily M member 4
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Gene · 54795

Papers1,538

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

1 to 20 of 1,538

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TitleJournalYearPMIDFound bySource
TRPM4 contributes to the formation and outgrowth of Dukes' stage C colorectal cancer tumor spheroids.Cell Calcium202642815047PubTator, text miningPubMed
Genetic loci responsible for atrioventricular block in children.Front Cell Dev Biol202642798645PubTator, text miningPubMed
Structural biology of the TRPM4 channel: architecture, modulation, and therapeutic opportunities.Front Pharmacol202642787536PubTator, text miningPubMed
Necrosis by Sodium Overload: Mechanisms, Pathophysiological Roles, and Therapeutic Prospects of a Novel Form of Regulated Cell Death.Cell Biochem Biophys202642709394PubTator, text miningPubMed
Construction of molecular signatures based on the co-expression network of NECSO-related gene TRPM4 and its prognostic value in hepatocellular carcinoma.J Gastrointest Oncol202642703320PubTator, text miningPubMed
Carrier-as-Prodrug Glycyrrhizic Acid Nanogel Co-Delivers Mannose and Glycyrrhetinic Acid for Metabolic-Ionic Cancer Therapy.ACS Appl Mater Interfaces202642670768PubTator, text miningPubMed
Integrated Analysis Identifies a TRPM4-Related Sodium Overload Signature with Prognostic Value and Experimentally Validates RNPEPL1 in Lung Adenocarcinoma.Cancers (Basel)202642649955PubTator, text miningPubMed
HOXC4 as a machine learning-derived immune biomarker for predicting treatment and prognosis in prostate cancer patients.Transl Androl Urol202642582767PubTator, text miningPubMed
NECSO-based classification predicts immunotherapy efficacy and identifies FLAD1 as therapeutic target in kidney renal clear cell carcinoma.Front Immunol202642582320PubTator, text miningPubMed
[Role of programmed cell death in platinum resistance in ovarian cancer].Zhong Nan Da Xue Xue Bao Yi Xue Ban202642565580PubTator, text miningPubMed
A Postzygotic TRPM4 Variant in a Patient with Inflammatory Linear Verrucous Epidermal Nevus.Acta Derm Venereol202642446416PubTator, text miningPubMed
Ion Channels as Therapeutic Targets in Overactive Bladder: A Narrative Review of Mechanisms, Translational Evidence, and Current Gaps.Low Urin Tract Symptoms202642442769PubTator, text miningPubMed
TRP matters: a pilot study on expression of mRNA in the parotid glands and their benign tumors.Biochem Biophys Rep202642437085PubTator, text miningPubMed
Discovery of a Polymorphic Gene Fusion via Bottom-Up Chimeric RNA Prediction: Case Study.Methods Mol Biol202642400801PubTator, text miningPubMed
Metabolic crisis and TRPM4 activation cause QT prolongation in TANGO2 deficiency disorder.Cardiovasc Res202642389941PubTator, text miningPubMed
Current Topics of Progressive Cardiac Conduction Disease.J Arrhythm202642368294PubTator, text miningPubMed
Molecular actors of the Calcium signaling in the endothelial-to-mesenchymal transition: poorly explored therapeutic targets.Cell Calcium202642349327PubTator, text miningPubMed
Structural mechanism of Necrocide 1 activation of human TRPM4 that triggers necrosis by sodium overload.Nat Commun202642342693PubTator, text miningPubMed
Integrating genetically encoded fluorescent sensors to elucidate the spatiotemporal choreography of necrosis by sodium overload.Acta Biochim Biophys Sin (Shanghai)202642290278PubTator, text miningPubMed
Temperature and intrinsic Ca2+ reshape TRPM4 pharmacology.Nat Struct Mol Biol202642265346PubTator, text miningPubMed

gene-search-2026-11-11-0.2.0

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  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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