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Gene · 54822

TRPM7: transient receptor potential cation channel subfamily M member 7

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. TRPM7: transient receptor potential cation channel subfamily M member 7. Genes, record 54822. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/54822

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Gene

Symbol
TRPM7
HGNC
Name
transient receptor potential cation channel subfamily M member 7
HGNC
NCBI Gene ID
54822
NCBI Gene
HGNC ID
HGNC:17994
HGNC
Ensembl
ENSG00000092439
NCBI Gene
Aliases
ALSPDC, CHAK, CHAK1, LTRPC7, LTrpC-7, TRP-PLIK
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q96QT4Transient receptor potential cation channel subfamily M member 71,8650Ensembl, GeneID, HGNC

Source UniProt

Patents20

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1467648Q96QT4Espacenet
EP 4641201 A22025-10-2925010Q96QT4Espacenet
JP 2025529142 A2025-09-045074Q96QT4Espacenet
US 12371689 B22025-07-295074Q96QT4Espacenet
JP 2025517969 A2025-06-1225010Q96QT4Espacenet
US 11446398 B22022-09-2090360Q96QT4Espacenet
US 11400116 B22022-08-024320Q96QT4Espacenet
JP 2022524081 A2022-04-27193331Q96QT4Espacenet
US 11078247 B22021-08-0312039Q96QT4Espacenet
JP 2019054813 A2019-04-11248083Q96QT4Espacenet

1 to 10 of 20

See all 20 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,313

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleTRPM7 papersNewest fiscal year
P20GM103466HAWAII INBRE V PROGRAM232025
R01DE017102TRPC1, Calcium, and Saliva Secretion122025
R01ES010563Mechanisms of Manganese Neurotoxicity72025
P30CA068485Cancer Center Support Grant62025
P30DK058404Molecular and Cellular Basis for Digestive Diseases62025
R01CA206573Structure and function of Transient Receptor Potential Channels52025
P30CA086862Cancer Center Support Grant42025
P50AA011999Southern California Research Center for ALPD and Cirrhosis42025
R01AT011162Modulation of pain mechanisms by cannabis-derived phytochemicals.42025
R01GM093290Regulation of the epithelial Ca2+ channels TRPV6 and TRPV542025

1 to 10 of 1,313Source NIH's project files

See all 1,313 nih grants

Papers2,329

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
A Boolean Seven-Layer Platelet Decision Model Models Consistently the Logic and Semiquantitatively the Dynamics of Platelet Activation and Inhibition.Comput Struct Biotechnol J202642819776PubTator, text miningPubMed
Mechanobiology of Osteoarthritis: Interactions Between Mechanical Stress, Inflammation, and Joint Remodeling.Cell Biol Int202642808736PubTator, text miningPubMed
Correction to: Chronic cadmium exposure promotes TRPM7‑dependent acquisition of a myofibroblast‑like phenotype in pancreatic stellate cells.Cell Biol Toxicol202642773377PubTator, text miningPubMed
Natural product-derived TRPM7 channel inhibitors in neurological injury: Mechanisms, pharmacological potential and translational challenges.Br J Pharmacol202642760099PubTator, text miningPubMed
Reciprocal Coupling among Extracellular Matrix Mechanics, Mechanosensitive Ion Channels, and Cell Remodeling Behaviors.ACS Appl Mater Interfaces202642675897PubTator, text miningPubMed
A tumor microenvironment-responsive calcium overload nanoplatform inducing PANoptosis for enhanced cancer immunotherapy.Mater Today Bio202642576991PubTator, text miningPubMed
Drugging non-canonical kinases in cancer therapeutics: Molecular targets, underlying mechanisms and small-molecule inhibitors.Acta Pharm Sin B202642453394PubTator, text miningPubMed
TRPM7 Channel-Mediated Mitochondrial Oxidative Stress Induces Dysfunction of Müller Cells Under High Glucose and Low Mg2+ Stress.Front Biosci (Landmark Ed)202642411499PubTator, text miningPubMed
TRPM7 in Peripheral and Central Immune Cells: Emerging Roles in Neuroinflammation and Neurological Disease.Int J Mol Sci202642352884PubTator, text miningPubMed
Biomarkers for assessing magnesium status.Adv Clin Chem202642336500PubTator, text miningPubMed

1 to 10 of 2,329

See all 2,329 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/54822

GET https://conductscience.org/api/genes/v1/54822/patents