Gene · 5498
PPOX: protoporphyrinogen oxidase
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. PPOX: protoporphyrinogen oxidase. Genes, record 5498. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/5498
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| P50336 | Protoporphyrinogen oxidase | 477 | 3 | Ensembl, GeneID, HGNC |
Source UniProt
Patents62
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026067851 A | 2026-04-21 | 103 | P50336 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 60389 | P50336 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 60390 | P50336 | Espacenet |
| JP 2025147176 A | 2025-10-06 | 10679 | P50336 | Espacenet |
| JP 2025147176 A | 2025-10-06 | 10680 | P50336 | Espacenet |
| JP 2025529142 A | 2025-09-04 | 7410 | P50336 | Espacenet |
| US 12371689 B2 | 2025-07-29 | 7410 | P50336 | Espacenet |
| JP 2025028160 A | 2025-02-28 | 10679 | P50336 | Espacenet |
| JP 2025028160 A | 2025-02-28 | 10680 | P50336 | Espacenet |
| KR 1020250010750 A | 2025-01-21 | 10679 | P50336 | Espacenet |
1 to 10 of 62
See all 62 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants345
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | PPOX papers | Newest fiscal year |
|---|---|---|---|
| U54DK110858 | Center for Iron & Heme Disorders at the University of Utah | 8 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 5 | 2025 |
| R01DK074797 | Inter-organ signaling in heme metabolism and organismal homeostasis. | 3 | 2025 |
| P30CA015704 | Cancer Center Support Grant | 2 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 2 | 2025 |
| P30DK026743 | UCSF Liver Center | 2 | 2025 |
| R01DK098672 | Regulation of Mitochondrial Function by Orphan Protein Phosphatases | 2 | 2025 |
| K08DK129716 | Cellular Signaling Pathways in the Regulation of Fetal Hemoglobin for Treatment of Sickle Cell Disease | 1 | 2025 |
| K12HD052896 | Child Health Research Career Development Award (CHRCDA) Program (K12) | 1 | 2025 |
| K23AR079586 | Measuring and Understanding Light Sensitivity in Erythropoietic Protoporphyria | 1 | 2025 |
1 to 10 of 345Source NIH's project files
See all 345 nih grantsPapers1,642
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Hydrodynamic Cavitation in Juice Processing: Linking PME, PPO, and POD Responses to Physicochemical Stability and Quality Retention. | Molecules | 2026 | 42796607 | PubTator, text mining | PubMed |
| Spatiotemporal Dissection of the Infection Response to Bacterial Soft Rot in Non-heading Chinese cabbage. | Plant Dis | 2026 | 42754990 | PubTator, text mining | PubMed |
| Potential mitochondria-associated pathogenic genes in sepsis: a multi-omics Mendelian randomization study. | Front Immunol | 2026 | 42694092 | PubTator, text mining | PubMed |
| Effects of Electrolyzed Functional Water Combined with Modified Atmosphere Storage on Postharvest Quality of Arrow Bamboo Shoots. | Foods | 2026 | 42650592 | PubTator, text mining | PubMed |
| Integrated transcriptomic and metabolomic analyses reveal the regulatory network of alkaloid metabolism in blister blight-infected tea plants. | Front Plant Sci | 2026 | 42621026 | PubTator, text mining | PubMed |
| Tri-frequency ultrasonication priming enhances germination, nutritional quality and techno-functional properties of tartary buckwheat. | Ultrason Sonochem | 2026 | 42604605 | PubTator, text mining | PubMed |
| Draft Genome Assembly and Differential Expression of MpPPO1 and MpPPO2 Across Green-Fruit Development in Ecuadorian Musa paradisiaca L. | Plants (Basel) | 2026 | 42588832 | PubTator, text mining | PubMed |
| High frequency of the PPOX p.Arg168His pathogenic variant among Brazilian patients with variegate porphyria. | Mol Genet Metab | 2026 | 42566979 | PubTator, text mining | PubMed |
| Challenges in Porphyria diagnosis and management: When variegate Porphyria meets HIV. | Mol Genet Metab | 2026 | 42566978 | PubTator, text mining | PubMed |
| Molecular insights into the anti-browning effect of protocatechualdehyde. | Int J Biol Macromol | 2026 | 42551667 | PubTator, text mining | PubMed |
1 to 10 of 1,642
See all 1,642 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/5498
GET https://conductscience.org/api/genes/v1/5498/patents?page=2