Gene · 5500
PPP1CB: protein phosphatase 1 catalytic subunit beta
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. PPP1CB: protein phosphatase 1 catalytic subunit beta. Genes, record 5500. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/5500
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| P62140 | Serine/threonine-protein phosphatase PP1-beta catalytic subunit | 327 | 0 | Ensembl, GeneID, HGNC |
Source UniProt
Patents66
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 59831 | P62140 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 59832 | P62140 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 59833 | P62140 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 3686 | P62140 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 3281 | P62140 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 3281 | P62140 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 3686 | P62140 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 68442 | P62140 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 68443 | P62140 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 68444 | P62140 | Espacenet |
1 to 10 of 66
See all 66 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,061
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | PPP1CB papers | Newest fiscal year |
|---|---|---|---|
| P30CA008748 | Cancer Center Support Grant | 9 | 2025 |
| P30AI117970 | District of Columbia Center for AIDS Research | 5 | 2025 |
| P30CA016520 | Abramson Cancer Center Support Grant | 4 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 4 | 2025 |
| R01AG011085 | Ubiquitin‐mediated proteolysis and cell cycle control | 4 | 2025 |
| P30CA036727 | Buffett Cancer Center Support Grant | 3 | 2025 |
| P30CA046934 | University of Colorado Cancer Center Support Grant | 3 | 2025 |
| P30CA068485 | Cancer Center Support Grant | 3 | 2025 |
| R35GM127289 | Cyclin-dependent kinase control of cell-division and transcription cycles | 3 | 2025 |
| U54MD007597 | Howard University Research Center for Minority Health and Health Disparities | 3 | 2025 |
1 to 10 of 1,061Source NIH's project files
See all 1,061 nih grantsPapers1,416
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Thoracic Aortic Disease in Genetic Syndromes Beyond Established Aortopathy Genes. | medRxiv | 2026 | 42818859 | PubTator, text mining | PubMed |
| S-palmitoylation stabilizes OGT and the OGT-PPP1CC complex. | Acta Biochim Biophys Sin (Shanghai) | 2026 | 42784431 | PubTator, text mining | PubMed |
| PPP1CB-Related Noonan Syndrome with Loose Anagen Hair: A Systematic Review. | Genes (Basel) | 2026 | 42353762 | PubTator, text mining | PubMed |
| Lipid Metabolic Rewiring During Continuous Prostate Cancer Progression Defines a Biologically Relevant Four-Gene Prognostic Signature. | Biol Proced Online | 2026 | 42185987 | PubTator, text mining | PubMed |
| Ultrasensitive non-enzymatic protein detection using proximity immunoassay with photonic resonator absorption microscopy. | NPJ Biosens | 2026 | 42164720 | PubTator, text mining | PubMed |
| A Patient With Novel PPP1CB -ALK Fusion Advanced NSCLC Achieved Long Survival From Alectinib: A Case Report. | JTO Clin Res Rep | 2026 | 42158271 | PubTator, text mining | PubMed |
| A rare RASopathy: Noonan syndrome-like disorder with loose anagen hair caused by a protein phosphatase 1 catalytic subunit beta pathogenic variant. | Clin Dysmorphol | 2026 | 42059183 | PubTator, text mining | PubMed |
| Clinical and Genetic Characterization of Noonan Syndrome in a Colombian Pediatric Cohort | J Clin Res Pediatr Endocrinol | 2026 | 41988663 | PubTator, text mining | PubMed |
| Alternative Polyadenylation Signatures Distinguish Maladaptive Right Ventricular Remodeling in Pulmonary Hypertension: Implications for RNA-Based Diagnostics and Therapeutics. | Br J Biomed Sci | 2026 | 41799857 | PubTator, text mining | PubMed |
| The CD97-PPM1G axis dampens antiviral immunity by dephosphorylating IRF7 in type I interferon pathway. | PLoS Pathog | 2026 | 41774756 | PubTator, text mining | PubMed |
1 to 10 of 1,416
See all 1,416 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/5500
GET https://conductscience.org/api/genes/v1/5500/patents?page=2