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ANO1: anoctamin 1

1 protein, 29 patents, 1 drug, 10 trials, 1,645 NIH grants and 4,739 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolANO1HGNC
Nameanoctamin 1HGNC
NCBI Gene ID55107NCBI Gene
HGNC IDHGNC:21625HGNC
EnsemblENSG00000131620NCBI Gene
AliasesDOG1, FLJ10261, INDMS, MYMY7, ORAOV2, TAOS2, TMEM16ANCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
Q5XXA6Anoctamin-19860Ensembl, GeneID, HGNCUniProt

Patents 29

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1437586Q5XXA6Espacenet
US 12516308 B22026-01-062442Q5XXA6Espacenet
EP 4650780 A22025-11-197155Q5XXA6Espacenet
EP 4640849 A22025-10-291052Q5XXA6Espacenet
EP 4641201 A22025-10-297069Q5XXA6Espacenet
JP 2025529142 A2025-09-04393Q5XXA6Espacenet
US 12371689 B22025-07-29393Q5XXA6Espacenet
JP 2025519096 A2025-06-241052Q5XXA6Espacenet
JP 2025517969 A2025-06-127069Q5XXA6Espacenet
JP 2025517970 A2025-06-127155Q5XXA6Espacenet

Drugs 1

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource
CROFELEMERCHEMBL2108184Anoctamin-1 blockerBLOCKERChEMBL

Trials 10

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource
NCT06904872CROFELEMERPHASE2ClinicalTrials.gov
NCT06721871CROFELEMERPHASE2/PHASE3ClinicalTrials.gov
NCT06326645CROFELEMEREARLY_PHASE1ClinicalTrials.gov
NCT04486326CROFELEMERPHASE42026-03-10ClinicalTrials.gov
NCT03094052CROFELEMERPHASE22023-11-18ClinicalTrials.gov
NCT01374490CROFELEMERPHASE32020-08-17ClinicalTrials.gov
NCT00547898CROFELEMERPHASE32020-09-03ClinicalTrials.gov
NCT00461526CROFELEMERPHASE2ClinicalTrials.gov
NCT00002408CROFELEMERPHASE3ClinicalTrials.gov
NCT00002310CROFELEMERClinicalTrials.gov

NIH grants 1645

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
R01DK057061Calcium Dynamics in Interstitial Cells of Cajal252,025NIH's project files
P30CA008748Cancer Center Support Grant242,025NIH's project files
P30DK084567Mayo Center for Cell Signaling in Gastroenterology162,025NIH's project files
P30DK065988UNC Cystic Fibrosis Research and Translation Core Center142,025NIH's project files
R01DK120759Role of interstitial cells of Cajal in patterned colonic motor activity132,025NIH's project files
P30DK072482UAB CF Research and Translation Core Center102,025NIH's project files
R01DK057236Electrophysiological Events Underlying Human Gastric Motility.102,025NIH's project files
P30EY006360P30-Core Grant for Vision Research92,025NIH's project files
ZIABC011427Immunohistochemical and genomic analysis of tumors92,025NIH's project files
R01CA102613Molecular Mechanisms in Gastrointestinal Stromal Tumor82,025NIH's project files

Papers 4739

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42813336PubTator, text miningPubMed
42801293PubTator, text miningPubMed
42797787PubTator, text miningPubMed
42781007PubTator, text miningPubMed
42778800PubTator, text miningPubMed
42761781PubTator, text miningPubMed
42761235PubTator, text miningPubMed
42757972PubTator, text miningPubMed
42755004PubTator, text miningPubMed
42754357PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license