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Gene · 55120

FANCL: FA complementation group L

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. FANCL: FA complementation group L. Genes, record 55120. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/55120

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Gene

Symbol
FANCL
HGNC
Name
FA complementation group L
HGNC
NCBI Gene ID
55120
NCBI Gene
HGNC ID
HGNC:20748
HGNC
Ensembl
ENSG00000115392
NCBI Gene
Aliases
FAAP43, FLJ10335, PHF9, POG, Pog
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q9NW38E3 ubiquitin-protein ligase FANCL3758Ensembl, GeneID, HGNC

Source UniProt

Patents20

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1445851Q9NW38Espacenet
EP 4650780 A22025-11-19864Q9NW38Espacenet
EP 4641201 A22025-10-29609Q9NW38Espacenet
JP 2025517969 A2025-06-12609Q9NW38Espacenet
JP 2025517970 A2025-06-12864Q9NW38Espacenet
US 11708396 B22023-07-252218Q9NW38Espacenet
US 11446398 B22022-09-2030682Q9NW38Espacenet
JP 2022524081 A2022-04-27133653Q9NW38Espacenet
US 10724100 B22020-07-289Q9NW38Espacenet
JP 2019054813 A2019-04-11226286Q9NW38Espacenet

1 to 10 of 20

See all 20 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,183

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleFANCL papersNewest fiscal year
P30CA016672Cancer Center Support Grant142025
P30CA008748Cancer Center Support Grant112025
ZIAAG000688Investigate the DNA damage response pathway of Fanconi anemia and BRCA proteins112025
ZIAHG000029Fanconi Anemia: Genotype-Phenotype Correlations112025
P30CA006973Regional Oncology Research Center92025
ZIACP010144Clinical Genetic Studies of Familial and Hereditary Cancer Syndromes92025
P30CA015704Cancer Center Support Grant82025
R01HL052725Molecular Pathogenesis of Fanconi Anemia82025
P01CA092584Structural Cell Biology of DNA Repair Machines72025
UL1TR001866Developing, Demonstrating, and Disseminating Innovative Programs to Achieve Translational Success72025

1 to 10 of 1,183Source NIH's project files

See all 1,183 nih grants

Papers1,443

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Complement system-related gene signatures implicated in the recurrence of glioma.Transl Cancer Res202642445436PubTator, text miningPubMed
FANCI: from genome guardian to translational therapeutic target.Front Oncol202642444811PubTator, text miningPubMed
Real-world clinical outcomes, genetic testing patterns, and treatment patterns of patients with metastatic castration-resistant prostate cancer treated with olaparib monotherapy in the United States.Urol Oncol202642431822PubTator, text miningPubMed
Integrated Molecular Profiling Improves Subtype Classification and Reveals Inherited Susceptibility in Medulloblastoma: Insights From a Real-World Cohort.Cancer Med202642056683PubTator, text miningPubMed
Differential sensitivity of MCPH1- and BRCA2-deficient cancer cells to PARP-1 inhibition.PLoS One202641931484PubTator, text miningPubMed
Indel pattern-guided repair mapping reveals genome-wide DNA repair networks in CRISPR/Cas9 editing.Nucleic Acids Res202641891877PubTator, text miningPubMed
Micronuclei: origins, assays, mechanisms, diseases and treatments.Signal Transduct Target Ther202641888103PubTator, text miningPubMed
Genome-wide CRISPR screens identify the EXO1-CAF-1 pathway suppressing R-loop-associated DNA damage.Nucleic Acids Res202641841497PubTator, text miningPubMed
Detection of germline variants in human population chronically exposed to high level natural background radiation in Kerala coast.Genes Environ202641761368PubTator, text miningPubMed
A machine learning approach to a nine-SNP immunogenetic score for prognostic stratification in cervical cancer.Front Immunol202641727446PubTator, text miningPubMed

1 to 10 of 1,443

See all 1,443 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/55120

GET https://conductscience.org/api/genes/v1/55120/patents