Gene · 55120
FANCL: FA complementation group L
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. FANCL: FA complementation group L. Genes, record 55120. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/55120
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| Q9NW38 | E3 ubiquitin-protein ligase FANCL | 375 | 8 | Ensembl, GeneID, HGNC |
Source UniProt
Patents20
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 45851 | Q9NW38 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 864 | Q9NW38 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 609 | Q9NW38 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 609 | Q9NW38 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 864 | Q9NW38 | Espacenet |
| US 11708396 B2 | 2023-07-25 | 2218 | Q9NW38 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 30682 | Q9NW38 | Espacenet |
| JP 2022524081 A | 2022-04-27 | 133653 | Q9NW38 | Espacenet |
| US 10724100 B2 | 2020-07-28 | 9 | Q9NW38 | Espacenet |
| JP 2019054813 A | 2019-04-11 | 226286 | Q9NW38 | Espacenet |
1 to 10 of 20
See all 20 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,183
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | FANCL papers | Newest fiscal year |
|---|---|---|---|
| P30CA016672 | Cancer Center Support Grant | 14 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 11 | 2025 |
| ZIAAG000688 | Investigate the DNA damage response pathway of Fanconi anemia and BRCA proteins | 11 | 2025 |
| ZIAHG000029 | Fanconi Anemia: Genotype-Phenotype Correlations | 11 | 2025 |
| P30CA006973 | Regional Oncology Research Center | 9 | 2025 |
| ZIACP010144 | Clinical Genetic Studies of Familial and Hereditary Cancer Syndromes | 9 | 2025 |
| P30CA015704 | Cancer Center Support Grant | 8 | 2025 |
| R01HL052725 | Molecular Pathogenesis of Fanconi Anemia | 8 | 2025 |
| P01CA092584 | Structural Cell Biology of DNA Repair Machines | 7 | 2025 |
| UL1TR001866 | Developing, Demonstrating, and Disseminating Innovative Programs to Achieve Translational Success | 7 | 2025 |
1 to 10 of 1,183Source NIH's project files
See all 1,183 nih grantsPapers1,443
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Complement system-related gene signatures implicated in the recurrence of glioma. | Transl Cancer Res | 2026 | 42445436 | PubTator, text mining | PubMed |
| FANCI: from genome guardian to translational therapeutic target. | Front Oncol | 2026 | 42444811 | PubTator, text mining | PubMed |
| Real-world clinical outcomes, genetic testing patterns, and treatment patterns of patients with metastatic castration-resistant prostate cancer treated with olaparib monotherapy in the United States. | Urol Oncol | 2026 | 42431822 | PubTator, text mining | PubMed |
| Integrated Molecular Profiling Improves Subtype Classification and Reveals Inherited Susceptibility in Medulloblastoma: Insights From a Real-World Cohort. | Cancer Med | 2026 | 42056683 | PubTator, text mining | PubMed |
| Differential sensitivity of MCPH1- and BRCA2-deficient cancer cells to PARP-1 inhibition. | PLoS One | 2026 | 41931484 | PubTator, text mining | PubMed |
| Indel pattern-guided repair mapping reveals genome-wide DNA repair networks in CRISPR/Cas9 editing. | Nucleic Acids Res | 2026 | 41891877 | PubTator, text mining | PubMed |
| Micronuclei: origins, assays, mechanisms, diseases and treatments. | Signal Transduct Target Ther | 2026 | 41888103 | PubTator, text mining | PubMed |
| Genome-wide CRISPR screens identify the EXO1-CAF-1 pathway suppressing R-loop-associated DNA damage. | Nucleic Acids Res | 2026 | 41841497 | PubTator, text mining | PubMed |
| Detection of germline variants in human population chronically exposed to high level natural background radiation in Kerala coast. | Genes Environ | 2026 | 41761368 | PubTator, text mining | PubMed |
| A machine learning approach to a nine-SNP immunogenetic score for prognostic stratification in cervical cancer. | Front Immunol | 2026 | 41727446 | PubTator, text mining | PubMed |
1 to 10 of 1,443
See all 1,443 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/55120
GET https://conductscience.org/api/genes/v1/55120/patents