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Gene · 55143

CDCA8: cell division cycle associated 8

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. CDCA8: cell division cycle associated 8. Genes, record 55143. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/55143

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Gene

Symbol
CDCA8
HGNC
Name
cell division cycle associated 8
HGNC
NCBI Gene ID
55143
NCBI Gene
HGNC ID
HGNC:14629
HGNC
Ensembl
ENSG00000134690
NCBI Gene
Aliases
BOR, BOREALIN, DasraB, FLJ12042, MESRGP
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q53HL2Borealin28015Ensembl, GeneID, HGNC

Source UniProt

Patents49

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1440808Q53HL2Espacenet
JP 2026004568 A2026-01-1440809Q53HL2Espacenet
EP 4641202 A22025-10-294905Q53HL2Espacenet
KR 1020250017231 A2025-02-044905Q53HL2Espacenet
US 11446398 B22022-09-2013804Q53HL2Espacenet
US 11446398 B22022-09-2013805Q53HL2Espacenet
JP 2022092366 A2022-06-22694Q53HL2Espacenet
JP 2022524081 A2022-04-27116775Q53HL2Espacenet
JP 2022524081 A2022-04-27116776Q53HL2Espacenet
JP 2021175409 A2021-11-0458Q53HL2Espacenet

1 to 10 of 49

See all 49 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants717

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleCDCA8 papersNewest fiscal year
P30CA008748Cancer Center Support Grant42025
P30CA044579University of Virginia Cancer Center Support Grant42025
P30CA015083Mayo Clinic Comprehensive Cancer Center Support Grant32025
P30CA016672Cancer Center Support Grant32025
P30CA076292Moffitt Cancer Center Support Grant32025
K12CA090628Paul Calabresi Program in Clinical/Translational Research at Mayo Clinic22025
P30CA006927Comprehensive Cancer Center Program at Fox Chase22025
P30CA013148Comprehensive Cancer Center Support Grant22025
P30CA014195Cancer Center Support Grant (CCSG)22025
P30CA016058Cancer Center Support Grant22025

1 to 10 of 717Source NIH's project files

See all 717 nih grants

Papers1,592

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
KDM1A/HDAC2-driven epigenetic dysregulation maintains a drug-resistant, relapse-initiating glioblastoma cell niche at the peri-tumoral margin.Biochem Pharmacol202642685875PubTator, text miningPubMed
CDCA8 regulates ATP5F1A protein stability and malignant phenotypes in wilms tumor cells: Prognostic implications and mechanistic insights.PLoS One202642479720PubTator, text miningPubMed
SIX1 branchio-oto-renal syndrome variants have different effects on embryonic craniofacial gene expression and cartilage formation.Development202642290293PubTator, text miningPubMed
Design, synthesis, and biological evaluation of a potent and selective AURKB degrader.Eur J Med Chem202642263581PubTator, text miningPubMed
Uncovering Prognostic Biomarkers Underlying Hepatocellular Carcinoma Through Integrative Multi-Omics and a Network-Based Approach.Int J Mol Sci202642196147PubTator, text miningPubMed
Integrative Bioinformatic Analysis Identifies Key Genes Driving Breast Cancer Brain Metastasis.Diagnostics (Basel)202642072775PubTator, text miningPubMed
YBX1 promotes the stemness and metastasis of NSCLC cells by promoting CDCA8 expression.Neoplasma202642054276PubTator, text miningPubMed
A macrophage MHC-I axis links intratumoral heterogeneity to terminal CD8+ T cell exhaustion in lung adenocarcinoma.NPJ Precis Oncol202642031958PubTator, text miningPubMed
USP35 Acts as a Dual Stabilizer of CDCA8 and PD-L1 to Coordinate the Progression and Immune Evasion in Non-Small Cell Lung Cancer.Comb Chem High Throughput Screen202642002994PubTator, text miningPubMed
Mitotic error correction and the spindle assembly checkpoint: a tension-filled relationship.Cell Cycle202641930946PubTator, text miningPubMed

1 to 10 of 1,592

See all 1,592 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/55143

GET https://conductscience.org/api/genes/v1/55143/patents?page=2