Gene · 55143
CDCA8: cell division cycle associated 8
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. CDCA8: cell division cycle associated 8. Genes, record 55143. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/55143
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| Q53HL2 | Borealin | 280 | 15 | Ensembl, GeneID, HGNC |
Source UniProt
Patents49
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 40808 | Q53HL2 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 40809 | Q53HL2 | Espacenet |
| EP 4641202 A2 | 2025-10-29 | 4905 | Q53HL2 | Espacenet |
| KR 1020250017231 A | 2025-02-04 | 4905 | Q53HL2 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 13804 | Q53HL2 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 13805 | Q53HL2 | Espacenet |
| JP 2022092366 A | 2022-06-22 | 694 | Q53HL2 | Espacenet |
| JP 2022524081 A | 2022-04-27 | 116775 | Q53HL2 | Espacenet |
| JP 2022524081 A | 2022-04-27 | 116776 | Q53HL2 | Espacenet |
| JP 2021175409 A | 2021-11-04 | 58 | Q53HL2 | Espacenet |
1 to 10 of 49
See all 49 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants717
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | CDCA8 papers | Newest fiscal year |
|---|---|---|---|
| P30CA008748 | Cancer Center Support Grant | 4 | 2025 |
| P30CA044579 | University of Virginia Cancer Center Support Grant | 4 | 2025 |
| P30CA015083 | Mayo Clinic Comprehensive Cancer Center Support Grant | 3 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 3 | 2025 |
| P30CA076292 | Moffitt Cancer Center Support Grant | 3 | 2025 |
| K12CA090628 | Paul Calabresi Program in Clinical/Translational Research at Mayo Clinic | 2 | 2025 |
| P30CA006927 | Comprehensive Cancer Center Program at Fox Chase | 2 | 2025 |
| P30CA013148 | Comprehensive Cancer Center Support Grant | 2 | 2025 |
| P30CA014195 | Cancer Center Support Grant (CCSG) | 2 | 2025 |
| P30CA016058 | Cancer Center Support Grant | 2 | 2025 |
1 to 10 of 717Source NIH's project files
See all 717 nih grantsPapers1,592
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| KDM1A/HDAC2-driven epigenetic dysregulation maintains a drug-resistant, relapse-initiating glioblastoma cell niche at the peri-tumoral margin. | Biochem Pharmacol | 2026 | 42685875 | PubTator, text mining | PubMed |
| CDCA8 regulates ATP5F1A protein stability and malignant phenotypes in wilms tumor cells: Prognostic implications and mechanistic insights. | PLoS One | 2026 | 42479720 | PubTator, text mining | PubMed |
| SIX1 branchio-oto-renal syndrome variants have different effects on embryonic craniofacial gene expression and cartilage formation. | Development | 2026 | 42290293 | PubTator, text mining | PubMed |
| Design, synthesis, and biological evaluation of a potent and selective AURKB degrader. | Eur J Med Chem | 2026 | 42263581 | PubTator, text mining | PubMed |
| Uncovering Prognostic Biomarkers Underlying Hepatocellular Carcinoma Through Integrative Multi-Omics and a Network-Based Approach. | Int J Mol Sci | 2026 | 42196147 | PubTator, text mining | PubMed |
| Integrative Bioinformatic Analysis Identifies Key Genes Driving Breast Cancer Brain Metastasis. | Diagnostics (Basel) | 2026 | 42072775 | PubTator, text mining | PubMed |
| YBX1 promotes the stemness and metastasis of NSCLC cells by promoting CDCA8 expression. | Neoplasma | 2026 | 42054276 | PubTator, text mining | PubMed |
| A macrophage MHC-I axis links intratumoral heterogeneity to terminal CD8+ T cell exhaustion in lung adenocarcinoma. | NPJ Precis Oncol | 2026 | 42031958 | PubTator, text mining | PubMed |
| USP35 Acts as a Dual Stabilizer of CDCA8 and PD-L1 to Coordinate the Progression and Immune Evasion in Non-Small Cell Lung Cancer. | Comb Chem High Throughput Screen | 2026 | 42002994 | PubTator, text mining | PubMed |
| Mitotic error correction and the spindle assembly checkpoint: a tension-filled relationship. | Cell Cycle | 2026 | 41930946 | PubTator, text mining | PubMed |
1 to 10 of 1,592
See all 1,592 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/55143
GET https://conductscience.org/api/genes/v1/55143/patents?page=2