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PPP2CA: protein phosphatase 2 catalytic subunit alpha
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Gene · 5515

Papers3,188

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

1 to 20 of 3,188

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TitleJournalYearPMIDFound bySource
HIF-1-mediated PPME1 expression promotes breast cancer progression via AKT activation and β-catenin recruitment.J Clin Invest202642820287PubTator, text miningPubMed
A case report of a novel de novo variant in PPP2CA causing a neurodevelopmental disorder and epilepsy.Front Psychiatry202642630699PubTator, text miningPubMed
A PP2A phosphatase-defined transcriptional activity window safeguards male fertility.Plant Cell202642574602PubTator, text miningPubMed
Study of post-translational modifications of p53 in multiple myeloma.Blood Cancer J202642469225PubTator, text miningPubMed
The Protein Phosphatase Inhibitor LB100 Targets the Mesenchymal Lineage of Pancreatic Ductal Adenocarcinoma.MedComm (2020)202642266180PubTator, text miningPubMed
Correction: Colchicine inhibits vascular calcification by suppressing inflammasome activation through the enhancement of the Sirt2-PP2Ac signaling pathway.J Biol Chem202642242025PubTator, text miningPubMed
CYP2A13 upregulation contributes to lung tumorigenesis upon NNK exposure.Ecotoxicol Environ Saf202642217486PubTator, text miningPubMed
Mts/PP2AC Induces Cell Migration via Rho1-Slpr-Mediated JNK Pathway.FASEB J202642144974PubTator, text miningPubMed
Regulation between LRRK2 and PP2A signaling in cellular models of Parkinson's disease.Biochem J202642133347PubTator, text miningPubMed
Synthesis and characterization of L-3-(pentafluorophosphato-difluoromethyl)-alanine, a structural and functional mimetic of phosphoserine.Chem Commun (Camb)202642132578PubTator, text miningPubMed
Protein phosphatase 2A regulates senescence and immunogenicity in medulloblastoma models.J Clin Invest202642085538PubTator, text miningPubMed
Data Mining for Identification of Targets and Repurposed Drugs to Eliminate Persistent Chronic Myeloid Leukaemia Stem Cells: Targeting RAS/RAF Signalling.Oncol Res202642065040PubTator, text miningPubMed
Identification of peptides interfering with the PP2Ac And LRRK2 interaction.Biochim Biophys Acta Proteins Proteom202641990985PubTator, text miningPubMed
Template-driven scaffolding of SCFFBXO42 regulates PP2A degradation.Nature202641986709Swiss-Prot, curatedPubMed
Identification of potential diagnostic and therapeutic apoptosis-related casual targets for osteoporosis: an integrated multi-omics analysis.J Bone Miner Metab202641870631PubTator, text miningPubMed
Eugenol: A promising therapeutic terpenoid against ischemia-reperfusion injury.EXCLI J202641834914PubTator, text miningPubMed
O-GlcNAcylation of IGF2BP2 promotes angiogenesis after ischemic stroke by stabilizing PPP2CA in an m6A-dependent manner : O-GlcNAcylation of IGF2BP2 alleviates ischemic brain injury.J Transl Med202641832533PubTator, text miningPubMed
Study on the Potential Molecular Mechanisms of Sodium Dehydroacetate (Na-DHA) Interfering With Bone Metabolism and Inducing Osteoporosis Based on Network Toxicology, Molecular Docking, and In Vitro Experimental Validation.
Food Sci Nutr202641804343PubTator, text miningPubMed
Unravelling the Pathogenesis of Heart Failure with Preserved Ejection Fraction: The Pivotal Role of Autophagy and Endoplasmic Reticulum Stress.Eur Cardiol202641766770PubTator, text miningPubMed
Erratum: gp78-regulated KAP1 phosphorylation induces radioresistance in breast cancer by facilitating PPP1CC/PPP2CA ubiquitination.iScience202641756733PubTator, text miningPubMed

gene-search-2026-11-11-0.2.0

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  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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