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Gene · 55183

RIF1: replication timing regulatory factor 1

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. RIF1: replication timing regulatory factor 1. Genes, record 55183. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/55183

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Gene

Symbol
RIF1
HGNC
Name
replication timing regulatory factor 1
HGNC
NCBI Gene ID
55183
NCBI Gene
HGNC ID
HGNC:23207
HGNC
Ensembl
ENSG00000080345
NCBI Gene
Aliases
FLJ10599, FLJ12870
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q5UIP0Telomere-associated protein RIF12,4721Ensembl, GeneID, HGNC

Source UniProt

Patents40

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
EP 4650780 A22025-11-191088Q5UIP0Espacenet
EP 4641201 A22025-10-29763Q5UIP0Espacenet
JP 2025517969 A2025-06-12763Q5UIP0Espacenet
JP 2025517970 A2025-06-121088Q5UIP0Espacenet
EP 4464338 A22024-11-20298Q5UIP0Espacenet
JP 2024123008 A2024-09-108075Q5UIP0Espacenet
JP 2024123008 A2024-09-108080Q5UIP0Espacenet
US 11680268 B22023-06-20298Q5UIP0Espacenet
JP 2022141755 A2022-09-29427Q5UIP0Espacenet
US 11446398 B22022-09-2072664Q5UIP0Espacenet

1 to 10 of 40

See all 40 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants945

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleRIF1 papersNewest fiscal year
P30CA008748Cancer Center Support Grant122025
ZIABC010283DNA repair122025
ZIABC010959Relationship between DNA damage detection and signaling122025
P01CA092584Structural Cell Biology of DNA Repair Machines92025
P30CA016672Cancer Center Support Grant92025
R01GM083337cis-Acting Elements Regulating Developmental Control of Replication Timing92025
R01HL052725Molecular Pathogenesis of Fanconi Anemia62025
R35CA210036Genome instability in cancer: telomeres and DNA repair62025
ZIABC010411Initiation of DNA Replication in Mammalian Cells62025
P30CA047904Cancer Center Support Grant52025

1 to 10 of 945Source NIH's project files

See all 945 nih grants

Papers1,355

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
SRSF1 Maintains Sertoli Cell Proliferation and Survival by Regulating Alternative Splicing in Coordination With DDX5 and RBMX/RBMXL1.FASEB J202642764753PubTator, text miningPubMed
CDW19S coordinates phasic end processing via distinct enzymatic activities.Nucleic Acids Res202642406631PubTator, text miningPubMed
Deciphering the Pleiotropic Role of ARID1a and RIF1 in Endometrioid Ovarian Cancer.Cells202642274628PubTator, text miningPubMed
Adaptive Replication Fork Acceleration by CDK1-Cyclin B1 Sustains Genome Duplication despite Impaired Origin Firing.bioRxiv202642239157PubTator, text miningPubMed
53BP1 orchestrates sequence feature of RAG targets to balance DNA repair outcomes during V(D)J recombination.Sci Adv202642172328PubTator, text miningPubMed
NANOG Proximity Proteomics Maps Neighborhood Hubs Linked to Mesenchymal Stem Cell Stemness and Chromatin Control.Biomolecules202642072652PubTator, text miningPubMed
PICH facilitates iPSC reprogramming by alleviating genomic instability induced by DNA replication stress.FEBS J202641981724PubTator, text miningPubMed
Indel pattern-guided repair mapping reveals genome-wide DNA repair networks in CRISPR/Cas9 editing.Nucleic Acids Res202641891877PubTator, text miningPubMed
CBX2 phase-separation contributes to homologous recombination repair and drug resistance in ovarian cancer.Cell Death Dis202641888115PubTator, text miningPubMed
YTHDF3 facilitates DNA damage response by recognizing METTL3-mediated m6A modification to promote chemotherapy resistance in glioblastoma.Cancer Lett202641881336PubTator, text miningPubMed

1 to 10 of 1,355

See all 1,355 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/55183

GET https://conductscience.org/api/genes/v1/55183/patents?page=2