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Gene · 55188

RIC8B: RIC8 guanine nucleotide exchange factor B

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. RIC8B: RIC8 guanine nucleotide exchange factor B. Genes, record 55188. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/55188

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Gene

Symbol
RIC8B
HGNC
Name
RIC8 guanine nucleotide exchange factor B
HGNC
NCBI Gene ID
55188
NCBI Gene
HGNC ID
HGNC:25555
HGNC
Ensembl
ENSG00000111785
NCBI Gene
Aliases
FLJ10620, RIC8, hSyn
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q9NVN3Chaperone Ric-8B5200Ensembl, GeneID, HGNC

Source UniProt

Patents7

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
EP 4650780 A22025-11-1910965Q9NVN3Espacenet
JP 2025517970 A2025-06-1210965Q9NVN3Espacenet
US 11446398 B22022-09-2074610Q9NVN3Espacenet
JP 2022524081 A2022-04-27177581Q9NVN3Espacenet
JP 2017121240 A2017-07-1353590Q9NVN3Espacenet
JP 2015518704 A2015-07-0653590Q9NVN3Espacenet
EP 1716227 A22006-11-02166713Q9NVN3Espacenet

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants2,081

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleRIC8B papersNewest fiscal year
R01DC008983Contribution of striatum to central auditory processing92025
P51OD011132Emory National Primate Research Center82025
R01EY019049Processing and transformation of visual signals in the superior colliculus82025
R01MH101377Deconstruction of a Neural Circuit for Aggression82025
U19NS107616Oxytocin Modulation of Neural Circuit Function and Behavior72025
P30DK020541NYR-Diabetes Research Center (NYR-DRC)62025
R01MH104559ROLE OF PERIPHERAL IMMUNE-DERIVED MMP8 IN STRESS SUSCEPTIBILITY52025
P30CA008748Cancer Center Support Grant42025
R01MH054137Structure and Function of Dopamine Receptors42025
R01MH108924Dissecting basal ganglia circuits underlying motivated behaviors42025

1 to 10 of 2,081Source NIH's project files

See all 2,081 nih grants

Papers1,524

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Functions and trafficking mechanisms of RIC-8 in C. elegans and mammalian cilia.Mol Biol Cell202642307979PubTator, text miningPubMed
Design and initial characterization of a novel mini-promoter for gene therapies targeting the central nervous system.Mol Ther Adv202642137269PubTator, text miningPubMed
AAV9-Mediated Targeting of Defined Neuronal Populations in Spinal Cord Through Intrathecal Injection.Front Biosci (Elite Ed)202641914168PubTator, text miningPubMed
Distinct roles of cortical layer 5 subtypes in associative learning.Nat Commun202641862437PubTator, text miningPubMed
Protocol for genetic manipulation of cervical lymph node-innervating nociceptive neurons in mice via retrograde viral tracing.STAR Protoc202641855205PubTator, text miningPubMed
iGABASnFR2 is an improved genetically encoded protein sensor of GABA.Elife202641848771PubTator, text miningPubMed
MitoTracker transfers from astrocytes to neurons independently of mitochondria.Cell Rep Methods202641831447PubTator, text miningPubMed
Transcriptional regulation of ventral hippocampus-nucleus accumbens circuit excitability drives cocaine seeking.Sci Adv202641779851PubTator, text miningPubMed
Neuronal Cell-Cycle Re-entry Defines Divergent Outcomes Through Replication-Dependent DNA Damage in ALS.bioRxiv202641756973PubTator, text miningPubMed
Evolution of Engineered ADAR-Based RNA Editing Systems.Int J Mol Sci202641751993PubTator, text miningPubMed

1 to 10 of 1,524

See all 1,524 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/55188

GET https://conductscience.org/api/genes/v1/55188/grants?page=2