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Gene · 552

AVPR1A: arginine vasopressin receptor 1A

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. AVPR1A: arginine vasopressin receptor 1A. Genes, record 552. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/552

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Gene

Symbol
AVPR1A
HGNC
Name
arginine vasopressin receptor 1A
HGNC
NCBI Gene ID
552
NCBI Gene
HGNC ID
HGNC:895
HGNC
Ensembl
ENSG00000166148
NCBI Gene
Aliases
AVPR V1a, AVPR1, V1aR
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P37288Vasopressin V1a receptor4185Ensembl, GeneID, HGNC

Source UniProt

Patents37

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026062654 A2026-04-1056P37288Espacenet
JP 2026004568 A2026-01-1437809P37288Espacenet
EP 4650780 A22025-11-193920P37288Espacenet
EP 4641201 A22025-10-293496P37288Espacenet
JP 2025529142 A2025-09-04549P37288Espacenet
US 12371689 B22025-07-29549P37288Espacenet
JP 2025517969 A2025-06-123496P37288Espacenet
JP 2025517970 A2025-06-123920P37288Espacenet
JP 2025062604 A2025-04-146181P37288Espacenet
JP 2023156353 A2023-10-2456P37288Espacenet

1 to 10 of 37

See all 37 patents

Drugs15

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource
ARGIPRESSIN TANNATECHEMBL2108986Vasopressin receptor agonistAGONISTChEMBL
BALOVAPTANCHEMBL4297183Vasopressin V1a receptor antagonistANTAGONISTChEMBL
CONIVAPTANCHEMBL1755Vasopressin V1a receptor antagonistANTAGONISTChEMBL
CONIVAPTAN HYDROCHLORIDECHEMBL1201108Vasopressin V1a receptor antagonistANTAGONISTChEMBL
DESMOPRESSINCHEMBL1429Vasopressin receptor agonistAGONISTChEMBL
DESMOPRESSIN ACETATECHEMBL1200556Vasopressin receptor agonistAGONISTChEMBL
LYPRESSINCHEMBL1200690Vasopressin receptor agonistAGONISTChEMBL
PECAVAPTANCHEMBL4594444Vasopressin V1a receptor antagonistANTAGONISTChEMBL
RELCOVAPTANCHEMBL419667Vasopressin V1a receptor antagonistANTAGONISTChEMBL
SELEPRESSINCHEMBL1817709Vasopressin V1a receptor agonistAGONISTChEMBL

1 to 10 of 15

See all 15 drugs

Trials165

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

NIH grants928

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleAVPR1A papersNewest fiscal year
P51OD011132Emory National Primate Research Center242025
P51OD011107California National Primate Research Center152025
P30AG028740University of Florida Older Americans Independence Center (OAIC)72025
R35GM126940Emergent cellular functions of GPCRs and myosins42025
ZIAAA000301Integrative genetics of behavior with high throughput technologies42025
I01BX004102Oxytocin Signaling in the Control of Cardiometabolic Function in Diet-Induced Obesity32025
P30DK034989Yale Liver Center32025
R01HD098117Mechanisms of maternal brain changes with birth interventions32025
T32MH015144Research Training in Mood and Anxiety Disorders: From Animal Models to Patients32025
I01BX002773A Novel Drug Target for Aggressive Prostate Cancer22025

1 to 10 of 928Source NIH's project files

See all 928 nih grants

Papers1,367

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
SOMATODENDRITIC VASOPRESSIN RELEASE COUPLES INTRINSIC EXCITABILITY TO POPULATION-LEVEL ACTIVITY.bioRxiv202642818055PubTator, text miningPubMed
Important Role of Renin-Angiotensin System and Vasopressin System in Cardiovascular, Metabolic and Psychogenic Disorders in Pregnancy and Early Postnatal Life: A Narrative Review.Int J Mol Sci202642653310PubTator, text miningPubMed
A Multi-Method Approach to Investigate the Toxicity of Aristolochic Acid on Upper Tract Urothelial Carcinoma.Curr Med Chem202642565416PubTator, text miningPubMed
A yeast recombination system recapitulates the length polymorphism of a microsatellite implicated in human social behavior.NAR Mol Med202642367581PubTator, text miningPubMed
Expression and prognostic value of cholesterol homeostasis genes in hepatocellular carcinoma: A cohort study based on TCGA.Medicine (Baltimore)202642175500PubTator, text miningPubMed
Vasopressin 1a Receptor Antagonists for Pathological Aggression in Neurodegenerative and Other CNS Diseases.Biomedicines202642072430PubTator, text miningPubMed
Arginine-vasopressin systems in autistic phenotype schizophrenia: effect of a genetic variant of AVPR1a and AVPR1b.J Neural Transm (Vienna)202642047756PubTator, text miningPubMed
Imaging genetics insights into the association between polymorphisms of HPA-axis genes and brain function alterations in depressed adolescents.J Affect Disord202641935751PubTator, text miningPubMed
Integrated spatial transcriptomics and pan-cancer XGBoost modeling uncover spatial drivers of immune exclusion and predict immunotherapy response.Cancer Immunol Immunother202641925746PubTator, text miningPubMed
Molecular Boolean analyses of chemokine (C-C motif) receptor 1, α1B-adrenoceptor and arginine vasopressin receptor 1A heteromers.Biochem Biophys Rep202641867271PubTator, text miningPubMed

1 to 10 of 1,367

See all 1,367 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/552

GET https://conductscience.org/api/genes/v1/552/patents?page=2