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PTPA: protein phosphatase 2 phosphatase activator

1 protein, 10 patents, 0 drugs, 0 trials, 7,213 NIH grants and 12,393 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolPTPAHGNC
Nameprotein phosphatase 2 phosphatase activatorHGNC
NCBI Gene ID5524NCBI Gene
HGNC IDHGNC:9308HGNC
EnsemblENSG00000119383NCBI Gene
AliasesPARK25, PP2A, PPP2R4, PR53NCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
Q15257Serine/threonine-protein phosphatase 2A activator3586Ensembl, GeneID, HGNCUniProt

Patents 10

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1459985Q15257Espacenet
EP 4650780 A22025-11-196280Q15257Espacenet
JP 2025517970 A2025-06-126280Q15257Espacenet
US 11446398 B22022-09-2068813Q15257Espacenet
JP 2022524081 A2022-04-27171784Q15257Espacenet
WO 2020043864 A12020-03-051986Q15257Espacenet
JP 2019054813 A2019-04-11240420Q15257Espacenet
JP 2017121241 A2017-07-13240420Q15257Espacenet
JP 2015516143 A2015-06-08240420Q15257Espacenet
WO 2008115561 A22008-09-25143Q15257Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 7213

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA016672Cancer Center Support Grant572,025NIH's project files
P30CA008748Cancer Center Support Grant302,025NIH's project files
R35GM119455Mechanisms of Phosphorylation Signaling by Phosphoprotein Phosphatases292,025NIH's project files
P30CA068485Cancer Center Support Grant212,025NIH's project files
P30CA016058Cancer Center Support Grant202,025NIH's project files
P01CA097132Sphingolipids in Cancer Biology and Therapy182,025NIH's project files
P30CA006927Comprehensive Cancer Center Program at Fox Chase182,025NIH's project files
P30CA023108Cancer Center Support Grant162,025NIH's project files
P30CA076292Moffitt Cancer Center Support Grant162,025NIH's project files
P20GM113132The Institute for Biomolecular Targeting142,025NIH's project files

Papers 12393

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42816608PubTator, text miningPubMed
42809388PubTator, text miningPubMed
42788717PubTator, text miningPubMed
42784694PubTator, text miningPubMed
42762722PubTator, text miningPubMed
42749879PubTator, text miningPubMed
42749715PubTator, text miningPubMed
42742967PubTator, text miningPubMed
42736652PubTator, text miningPubMed
42727994PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license