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FBXW7: F-box and WD repeat domain containing 7

1 protein, 86 patents, 0 drugs, 0 trials, 3,780 NIH grants and 8,651 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolFBXW7HGNC
NameF-box and WD repeat domain containing 7HGNC
NCBI Gene ID55294NCBI Gene
HGNC IDHGNC:16712HGNC
EnsemblENSG00000109670NCBI Gene
AliasesAGO, CDC4, DEDHIL, FBW6, FBW7, FBX30, FBXW6, FLJ11071, SEL-10, SEL10, hAgo, hCdc4NCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
Q969H0F-box/WD repeat-containing protein 77077Ensembl, GeneID, HGNCUniProt

Patents 86

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
EP 4809117 A12026-09-231Q969H0Espacenet
JP 2026004568 A2026-01-1445984Q969H0Espacenet
EP 4641201 A22025-10-292692Q969H0Espacenet
US 12433888 B12025-10-0723Q969H0Espacenet
JP 2025147176 A2025-10-065173Q969H0Espacenet
JP 2025147176 A2025-10-065174Q969H0Espacenet
JP 2025147176 A2025-10-065175Q969H0Espacenet
EP 4623996 A22025-10-016Q969H0Espacenet
JP 2025529142 A2025-09-046350Q969H0Espacenet
US 12371689 B22025-07-296350Q969H0Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 3780

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA016672Cancer Center Support Grant1302,025NIH's project files
P30CA008748Cancer Center Support Grant992,025NIH's project files
P30CA021765Cancer Center Support Grant (CCSG)332,025NIH's project files
P30CA016087Cancer Center Support Grant242,025NIH's project files
R01AG011085Ubiquitin‐mediated proteolysis and cell cycle control232,025NIH's project files
P30CA016086Cancer Center Support Grant222,025NIH's project files
P30CA047904Cancer Center Support Grant222,025NIH's project files
P30CA006973Regional Oncology Research Center192,025NIH's project files
P30CA016058Cancer Center Support Grant192,025NIH's project files
P30CA046592University of Michigan Rogel Cancer Center Support Grant 2023-2028182,025NIH's project files

Papers 8651

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42824995PubTator, text miningPubMed
42801660PubTator, text miningPubMed
42777936PubTator, text miningPubMed
42776364PubTator, text miningPubMed
42768738PubTator, text miningPubMed
42726641PubTator, text miningPubMed
42719581PubTator, text miningPubMed
42682087PubTator, text miningPubMed
42648647PubTator, text miningPubMed
42631900PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license