Gene · 5531
PPP4C: protein phosphatase 4 catalytic subunit
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. PPP4C: protein phosphatase 4 catalytic subunit. Genes, record 5531. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/5531
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| P60510 | Serine/threonine-protein phosphatase 4 catalytic subunit | 307 | 0 | Ensembl, GeneID, HGNC |
Source UniProt
Patents31
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 59995 | P60510 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 3062 | P60510 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 3062 | P60510 | Espacenet |
| EP 4464338 A2 | 2024-11-20 | 183 | P60510 | Espacenet |
| US 11680268 B2 | 2023-06-20 | 183 | P60510 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 68864 | P60510 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 68866 | P60510 | Espacenet |
| JP 2022524081 A | 2022-04-27 | 171835 | P60510 | Espacenet |
| JP 2022524081 A | 2022-04-27 | 171837 | P60510 | Espacenet |
| US 11078247 B2 | 2021-08-03 | 8865 | P60510 | Espacenet |
1 to 10 of 31
See all 31 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,044
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | PPP4C papers | Newest fiscal year |
|---|---|---|---|
| R35GM119455 | Mechanisms of Phosphorylation Signaling by Phosphoprotein Phosphatases | 15 | 2025 |
| P20GM113132 | The Institute for Biomolecular Targeting | 10 | 2025 |
| P30CA023108 | Cancer Center Support Grant | 8 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 6 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 4 | 2025 |
| R01GM094231 | COMPUTATIONAL TOOLS FOR MASS SPECTROMETRY-BASED INTERACTOME DATA | 3 | 2025 |
| P01CA092584 | Structural Cell Biology of DNA Repair Machines | 2 | 2025 |
| P30CA015704 | Cancer Center Support Grant | 2 | 2025 |
| P30CA016087 | Cancer Center Support Grant | 2 | 2025 |
| P30CA033572 | Cancer Center Support Grant | 2 | 2025 |
1 to 10 of 1,044Source NIH's project files
See all 1,044 nih grantsPapers1,401
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| PP4 deficiency drives airway epithelial senescence via the PERK-eIF2α-ATF4-p21 axis in severe asthma. | Inflamm Res | 2026 | 42802286 | PubTator, text mining | PubMed |
| An integrated single-cell and Mendelian randomization analysis of stromal features in Asherman's syndrome and endometrial cancer. | Cancer Treat Res Commun | 2026 | 42727551 | PubTator, text mining | PubMed |
| CDK2-mediated phosphorylation of TRF1 S11 facilitates DNA damage repair by remodeling telomeric chromatin. | Cell Death Differ | 2026 | 42552398 | PubTator, text mining | PubMed |
| The regulation of protein phosphatase 4 by FBXO42 is required for cancer cell survival. | EMBO Rep | 2026 | 42448956 | PubTator, text mining | PubMed |
| Holding the PP2A and PP4 protein phosphatases at bay: emerging roles of FBXO42 and CCDC6. | EMBO Rep | 2026 | 42448955 | PubTator, text mining | PubMed |
| Translating transcriptomics analysis into diagnostic workflows: clinical variant identification and interpretation in hypothesis-driven and hypothesis-free approaches. | EBioMedicine | 2026 | 42208150 | PubTator, text mining | PubMed |
| Stage-specific biomarkers in triple-negative breast cancer: Preliminary findings from bioinformatics approaches. | Cancer Biomark | 2026 | 42206911 | PubTator, text mining | PubMed |
| Advancing PCOS drug development: multi-omics discovery of key targets and repurposable compounds. | Naunyn Schmiedebergs Arch Pharmacol | 2026 | 42171750 | PubTator, text mining | PubMed |
| The characteristics and mechanism of phosphorus adsorption and release of extracellular polymeric substances in biofilms based on phosphorus recovery. | Bioresour Technol | 2026 | 42128236 | PubTator, text mining | PubMed |
| Antibiotic-driven mechanisms in endogenous partial denitrification (EPD): Nitrite accumulation, microbial adaptation, functional gene responses and resistance gene proliferation. | J Hazard Mater | 2026 | 42096753 | PubTator, text mining | PubMed |
1 to 10 of 1,401
See all 1,401 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/5531
GET https://conductscience.org/api/genes/v1/5531/patents?page=2