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Gene · 5539

PPY: pancreatic polypeptide

11 sourcesgene-search-2026-11-11-0.1.0

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ConductScience Library. PPY: pancreatic polypeptide. Genes, record 5539. Release gene-search-2026-11-11-0.1.0, 11 Nov 2026. https://conductscience.org/library/genes/5539

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Gene

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

Symbol
PPY
HGNC
Name
pancreatic polypeptide
HGNC
NCBI Gene ID
5539
NCBI Gene
HGNC ID
HGNC:9327
HGNC
Ensembl
ENSG00000108849
NCBI Gene
Aliases
PH, PNP, PP
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P01298Pancreatic polypeptide prohormone953Ensembl, GeneID, HGNC

Source UniProt

Patents73

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
JP 2026088121 A2026-05-2811P01298Espacenet
JP 2026004568 A2026-01-1457042P01298Espacenet
EP 4650780 A22025-11-19654P01298Espacenet
JP 2025147176 A2025-10-0610716P01298Espacenet
JP 2025147176 A2025-10-0610717P01298Espacenet
JP 2025529142 A2025-09-047414P01298Espacenet
EP 4596042 A22025-08-0611P01298Espacenet
US 12371689 B22025-07-297414P01298Espacenet
JP 2025517970 A2025-06-12654P01298Espacenet
JP 2025028160 A2025-02-2810716P01298Espacenet

1 to 10 of 73

See all 73 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,759

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal year
P30DK020593Vanderbilt Diabetes Research Center202025
P30DK019525University of Pennsylvania Diabetes Research Center132025
ZIADK053200Diagnosis, Natural History, Management, tumor biology of Gastrinomas/PETs/Neuroendocrine tumors132025
P30DK020595Diabetes Research and Training Center112025
P30DK020579Diabetes Research Center102025
P30DK058404Molecular and Cellular Basis for Digestive Diseases92025
P01AI042288Immune Function and the Progression to Type 1 Diabetes82025
P30CA068485Cancer Center Support Grant82025
P30CA008748Cancer Center Support Grant72025
P30CA086862Cancer Center Support Grant72025

1 to 10 of 1,759Source NIH's project files

See all 1,759 nih grants

Papers4,248

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42782361PubTator, text miningPubMed
42634204PubTator, text miningPubMed
42615099PubTator, text miningPubMed
42531325PubTator, text miningPubMed
42447929PubTator, text miningPubMed
42321243PubTator, text miningPubMed
42274928PubTator, text miningPubMed
42268357PubTator, text miningPubMed
42215935PubTator, text miningPubMed
42168687PubTator, text miningPubMed

1 to 10 of 4,248

See all 4,248 papers

Sources 11

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNone stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GeneNone named. Public domain as US government information
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/5539

GET https://conductscience.org/api/genes/v1/5539/patents?page=2