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Gene · 55503

TRPV6: transient receptor potential cation channel subfamily V member 6

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. TRPV6: transient receptor potential cation channel subfamily V member 6. Genes, record 55503. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/55503

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Gene

Symbol
TRPV6
HGNC
Name
transient receptor potential cation channel subfamily V member 6
HGNC
NCBI Gene ID
55503
NCBI Gene
HGNC ID
HGNC:14006
HGNC
Ensembl
ENSG00000165125
NCBI Gene
Aliases
ABP/ZF, CAT1, CATL, CaT1, ECAC2, HRPTTN, HSA277909, LP6728, ZFAB
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q9H1D0Transient receptor potential cation channel subfamily V member 676525Ensembl, GeneID, HGNC

Source UniProt

Patents12

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2025529142 A2025-09-045081Q9H1D0Espacenet
US 12371689 B22025-07-295081Q9H1D0Espacenet
JP 2025032204 A2025-03-1137747Q9H1D0Espacenet
EP 4461818 A22024-11-1337747Q9H1D0Espacenet
JP 2024538787 A2024-10-231Q9H1D0Espacenet
KR 1020240099277 A2024-06-281Q9H1D0Espacenet
JP 2024505430 A2024-02-068Q9H1D0Espacenet
KR 1020230132450 A2023-09-152Q9H1D0Espacenet
JP 2023058610 A2023-04-2537747Q9H1D0Espacenet
US 11400116 B22022-08-024476Q9H1D0Espacenet

1 to 10 of 12

See all 12 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants905

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleTRPV6 papersNewest fiscal year
R01CA206573Structure and function of Transient Receptor Potential Channels182025
R01GM093290Regulation of the epithelial Ca2+ channels TRPV6 and TRPV5132025
R01NS107253Single-Particle Cryo-EM Characterization of AMPA Receptor Functional States102025
P30CA008748Cancer Center Support Grant72025
R01AR078814Structural and functional principles of activation and regulation of the transient receptor potential channel TRPV3.72025
P40OD010440Caenorhabditis Genetics Center62025
R01DE017102TRPC1, Calcium, and Saliva Secretion42025
U01DK108306UPMC Clinical Center for the Study of Chronic Pancreatitis and Diabetes42025
ZIAAI000300Genetic Aspects Of Viral Oncogenesis In Inbred Strains and Wild Mouse Species42025
P20GM103434West Virginia IDeA Network of Biomedical Research Excellence (WV-INBRE)32025

1 to 10 of 905Source NIH's project files

See all 905 nih grants

Papers1,976

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Tissue-Specific VDR Pathway Gene Expression Is Not Associated with Circulating 25OHD in Adolescents with Severe Obesity.Metabolites202642783752PubTator, text miningPubMed
Functional expression of TRPV6 in human syncytiotrophoblasts from trophoblast stem cells - possible role in maternal-fetal calcium transport.J Physiol Sci202642685659PubTator, text miningPubMed
Discovery of the small molecular inhibitors against TRPV6 as potential anti-cancer agents by structural based virtual screening.Front Chem202642582434PubTator, text miningPubMed
The Compound Terminalia Chebula Extract Alleviates PEDV-Induced Colonic Injury in Suckling Piglets by Enhancing Antioxidant Capacity, Suppressing Inflammation, Restoring Intestinal Function, and Inhibiting Viral Replication.
Animals (Basel)202642450791PubTator, text miningPubMed
Stanniocalcin 1 at the nexus of calcium homeostasis, IGF signaling, and cancer immunity.Endocr Rev202642446003PubTator, text miningPubMed
Synchronized Dietary Glucose and Amino Acid Supply Promotes Broiler Growth by Redirecting Metabolic Flux and Activating the AKT/mTORC1 Signaling Pathway.J Agric Food Chem202642366814PubTator, text miningPubMed
Structural characterization and functional evaluation of deer sinew peptide-calcium chelate for intestinal calcium transport and osteogenic differentiation.Int J Biol Macromol202642323995PubTator, text miningPubMed
Multimodal calcium coordination and transport mechanisms of cod bone-derived novel peptides DYGGEY and GESGEAGDR.Food Chem202642314480PubTator, text miningPubMed
Open-channel block of human TRPV6 by polyamine spermine.Nat Commun202642204171PubTator, text miningPubMed
TRPV6-Mediated Ca2+ Signaling in Pancreatic Ductal Adenocarcinoma: From Cellular Physiology to Therapeutic Opportunities.Cancers (Basel)202642193028PubTator, text miningPubMed

1 to 10 of 1,976

See all 1,976 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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