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Gene · 5552

SRGN: serglycin

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. SRGN: serglycin. Genes, record 5552. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/5552

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Gene

Symbol
SRGN
HGNC
Name
serglycin
HGNC
NCBI Gene ID
5552
NCBI Gene
HGNC ID
HGNC:9361
HGNC
Ensembl
ENSG00000122862
NCBI Gene
Aliases
PPG, PRG, PRG1
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P10124Serglycin1580Ensembl, GeneID, HGNC

Source UniProt

Patents66

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1463015P10124Espacenet
EP 4650780 A22025-11-191061P10124Espacenet
JP 2025147176 A2025-10-0612816P10124Espacenet
JP 2025529142 A2025-09-047805P10124Espacenet
US 12371689 B22025-07-297805P10124Espacenet
JP 2025517970 A2025-06-121061P10124Espacenet
JP 2025032204 A2025-03-1136489P10124Espacenet
JP 2025028160 A2025-02-2812816P10124Espacenet
KR 1020250010750 A2025-01-2112816P10124Espacenet
EP 4461818 A22024-11-1336489P10124Espacenet

1 to 10 of 66

See all 66 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants777

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleSRGN papersNewest fiscal year
P30CA016672Cancer Center Support Grant52025
P30CA068485Cancer Center Support Grant42025
P30AI027767UAB Center for AIDS Research (CFAR)22025
P30CA008748Cancer Center Support Grant22025
P30CA016042Cancer Center Support Grant22025
P30CA023168Cancer Center Support Grant22025
P30DK058404Molecular and Cellular Basis for Digestive Diseases22025
P30EY008126Core Grant in Vision Research22025
P41GM108538National Center for Quantitative Biology of Complex Systems22025
R01AR064327Reprogramming and Directed Differentiation of Skeletal Muscle Cells from hPSCs22025

1 to 10 of 777Source NIH's project files

See all 777 nih grants

Papers1,669

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Patients With Pancreatitis-Related Gene Variants Showed Higher Incidence of Hyperpancreatic Enzymemia After Endoscopic Retrograde Cholangiopancreatography.DEN Open202742058267PubTator, text miningPubMed
From Machine Learning-Enhanced Proteomics to a Validated Diagnostic Model: A Pipeline for Breast Cancer Biomarker Discovery via Independent and Transcriptomic Corroboration.Bioengineering (Basel)202642791912PubTator, text miningPubMed
Integrating machine learning and multi-omics analysis to identify and validate key genes associated with periodontitis.Acta Odontol Scand202642615493PubTator, text miningPubMed
A single-cell sequencing-based prognostic model reveals HLA-DRA, NPC2, and PRPF38B as immune-regulatory tumor suppressors in non-small cell lung cancer.Front Cell Dev Biol202642564225PubTator, text miningPubMed
Serglycin-ROS axis mediates synergistic lethality of PI3Kγ inhibition and Azacitidine in TP53-mutated AML.BMC Cancer202642464230PubTator, text miningPubMed
Integrative multi-omics profiling reveals coordinated immunometabolic reprogramming and host-microbiome interactions in acute pancreatitis.Front Immunol202642404879PubTator, text miningPubMed
Heparan Sulfate Proteoglycans in Immunity.Proteoglycan Res202642383138PubTator, text miningPubMed
Multi-omics analysis of kidney renal cell carcinoma in silico with preliminary in vivo validation.Front Immunol202642338588PubTator, text miningPubMed
Polyamine-related 4-gene prognostic signature in hepatocellular carcinoma.Medicine (Baltimore)202642332538PubTator, text miningPubMed
Serglycin Across the Disease Spectrum: A Multifunctional Proteoglycan in Inflammation and Cancer.Curr Issues Mol Biol202642193059PubTator, text miningPubMed

1 to 10 of 1,669

See all 1,669 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/5552

GET https://conductscience.org/api/genes/v1/5552/patents?page=2