Gene · 55553
SOX6: SRY-box transcription factor 6
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. SOX6: SRY-box transcription factor 6. Genes, record 55553. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/55553
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| P35712 | Transcription factor SOX-6 | 828 | 0 | Ensembl, GeneID, HGNC |
Source UniProt
Patents23
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 65436 | P35712 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 65440 | P35712 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 18670 | P35712 | Espacenet |
| JP 2025147176 A | 2025-10-06 | 15665 | P35712 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 18670 | P35712 | Espacenet |
| JP 2025032204 A | 2025-03-11 | 36308 | P35712 | Espacenet |
| JP 2025028160 A | 2025-02-28 | 15665 | P35712 | Espacenet |
| KR 1020250010750 A | 2025-01-21 | 15665 | P35712 | Espacenet |
| EP 4461818 A2 | 2024-11-13 | 36308 | P35712 | Espacenet |
| JP 2024109657 A | 2024-08-14 | 15504 | P35712 | Espacenet |
1 to 10 of 23
See all 23 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,650
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | SOX6 papers | Newest fiscal year |
|---|---|---|---|
| R01AR041398 | Novel Molecular Biomarkers of Bone Microarchitecture | 10 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 6 | 2025 |
| R01HG003988 | Functionally Assessing Transcriptional Enhancers In Vivo | 6 | 2025 |
| U19AG055373 | Trans-omics Integration of Multi-omics Studies for Osteoporosis | 6 | 2025 |
| P20GM109036 | Tulane COBRE for Clinical and Translational Research in Cardiometabolic Diseases | 5 | 2025 |
| P30CA043703 | Case Comprehensive Cancer Center Support Grant | 5 | 2025 |
| P30DK063491 | Diabetes Research Center (DRC) | 5 | 2025 |
| P01HD084387 | Developmental Mechanisms of Human Idiopathic Scoliosis | 4 | 2025 |
| UL1TR001863 | Yale Clinical and Translational Science Award | 4 | 2025 |
| P01AG036675 | Kynurenine accumulation drives loss of muscle and bone function with aging | 3 | 2025 |
1 to 10 of 1,650Source NIH's project files
See all 1,650 nih grantsPapers2,174
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| CRISPR activation reveals SOX5/6/9 as key transcriptional regulators directing iPSC-derived cells toward a notochordal lineage. | Stem Cell Reports | 2026 | 42660118 | PubTator, text mining | PubMed |
| Integrated analysis of MYH6, MYH7, and MYH7B expression and their associated microRNAs in human end-stage heart failure. | Front Cardiovasc Med | 2026 | 42630156 | PubTator, text mining | PubMed |
| Proteomic dynamics in endochondral ossification: insights from antler tip analysis. | PeerJ | 2026 | 42534826 | PubTator, text mining | PubMed |
| Epigenetic Patterns in Musculoskeletal Disease: Methylation of DKK1, RHOJ, and SOX6 Genes in Osteoarthritis and Osteoporosis. | Curr Issues Mol Biol | 2026 | 42510885 | PubTator, text mining | PubMed |
| Shared genetic architecture of Parkinson's disease and cutaneous melanoma: Heterogeneous pleiotropy and Colocalization at the SOX6 locus. | Prog Neuropsychopharmacol Biol Psychiatry | 2026 | 42335983 | PubTator, text mining | PubMed |
| Engineering functional ventral midbrain dopaminergic neurons in human organoids through WNT modulation and bioreactor culture. | Mol Psychiatry | 2026 | 42310192 | PubTator, text mining | PubMed |
| Integrated transcriptomic and functional analysis reveals tissue-specific molecular pathology in adolescent idiopathic scoliosis. | HGG Adv | 2026 | 42244182 | PubTator, text mining | PubMed |
| Ocular Manifestations of Infectious Salmon Anaemia Virus Infection in Atlantic Salmon (Salmo salar). | J Fish Dis | 2026 | 42226351 | PubTator, text mining | PubMed |
| The Transcription Factor SOX6 Regulates Autophagy Levels Through LAMP5 to Inhibit the Development of Pituitary Adenomas. | Appl Biochem Biotechnol | 2026 | 42012747 | PubTator, text mining | PubMed |
| LncRNA PSMB8-AS1 contributes to post-infarction heart failure by aggravating myocardial injury and inflammation. | Arch Biochem Biophys | 2026 | 41997398 | PubTator, text mining | PubMed |
1 to 10 of 2,174
See all 2,174 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/55553
GET https://conductscience.org/api/genes/v1/55553/patents?page=2