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AMBRA1: autophagy and beclin 1 regulator 1
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Gene · 55626

Papers1,468

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

1 to 20 of 1,468

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TitleJournalYearPMIDFound bySource
Spatial control of mitochondrial ubiquitination by the AMBRA1-RMC1-HUWE1 axis.Autophagy202642747977PubTator, text miningPubMed
Genome-wide CRISPR screen identifies AMBRA1 as a potential biomarker of response to platinum-based therapies in oral squamous cell carcinomas.iScience202642548798PubTator, text miningPubMed
Targeting Tex10 Overcomes Oxaliplatin Resistance by Competitively Disrupting the Non-Canonical BAF Complex in Colorectal Cancer.Adv Sci (Weinh)202642525468PubTator, text miningPubMed
Role of Autophagy in Goose Astrovirus-Induced Renal Injury in Goslings.Animals (Basel)202642511092PubTator, text miningPubMed
Utility of Combined Immunohistochemical Staining for AMBRA1 and Loricrin for Improving the Pathologic Diagnosis of High-Grade Dysplastic Nevi.Am J Dermatopathol202642358006PubTator, text miningPubMed
Ubiquitin-dependent degradation of p27Kip1 and p21Waf1/Cip1 by AMBRA1 ensures G1 and S phase progression and limits replication stress.Nucleic Acids Res202642339621PubTator, text miningPubMed
The Origin and Application of Cardiomyocyte-Derived Small Extracellular Vesicles: A Systematic Review.Int J Med Sci202642328115PubTator, text miningPubMed
Mitophagy mitigates tau acetylation via the ULK1-NAD+/SIRT1 axis in Alzheimer's disease.Autophagy202642323822PubTator, text miningPubMed
Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells.FEBS Open Bio202642231548PubTator, text miningPubMed
Trifloxystrobin-triggered Drp1 hyperactivation biases mitophagy and imposes long-lasting SVCV susceptibility in teleost.J Virol202642223444PubTator, text miningPubMed
Autophagy-centered gene networks reveal prognostic biomarkers and therapeutic targets in esophageal cancer.Discov Oncol202642204123PubTator, text miningPubMed
CRL4AMBRA1-mediated progesterone receptor degradation drives progestin resistance and represents a therapeutic vulnerability in endometrial cancer.Int J Biol Sci202642157930PubTator, text miningPubMed
Reduced ULK1 links impaired autophagy and mitophagy to Alzheimer's disease pathology.Nat Aging202642135576PubTator, text miningPubMed
Molecular modulators of cyclin-dependent kinase 4/6 inhibitor response in experimental glioma identified through genome-wide CRISPR-Cas9 screening.Neuro Oncol202642083788PubTator, text miningPubMed
AMBRA1 enhances Sonic Hedgehog signaling during cerebellar development and in medulloblastoma.Dev Cell202641980781PubTator, text miningPubMed
An interactome-based framework for DDB1- and CUL4-associated factor prioritization in targeted protein degradation.Mol Cell202641932313PubTator, text miningPubMed
Mechanism of action and clinical application of autophagy in multiple sclerosis (Review).Int J Mol Med202641860040PubTator, text miningPubMed
AMBRA1 activation alleviates zearalenone-induced swine testicular cell ferroptosis by facilitating mitophagy.J Anim Sci Biotechnol202641826991PubTator, text miningPubMed
BRAF inhibitor resistance in melanoma: from resistance mechanisms to therapeutic innovations.Mol Biomed202641807883PubTator, text miningPubMed
Beyond muscle weakness: pathogenesis of sepsis-induced myopathy and its management.Open Med (Wars)202641798907PubTator, text miningPubMed

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Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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