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Gene · 55636

CHD7: chromodomain helicase DNA binding protein 7

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. CHD7: chromodomain helicase DNA binding protein 7. Genes, record 55636. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/55636

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Gene

Symbol
CHD7
HGNC
Name
chromodomain helicase DNA binding protein 7
HGNC
NCBI Gene ID
55636
NCBI Gene
HGNC ID
HGNC:20626
HGNC
Ensembl
ENSG00000171316
NCBI Gene
Aliases
CRG, FLJ20357, FLJ20361, HH5, IS3, KAL5, KIAA1416
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q9P2D1ATP-dependent chromatin remodeler CHD72,9973Ensembl, GeneID, HGNC

Source UniProt

Patents27

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1441340Q9P2D1Espacenet
JP 2026004568 A2026-01-1441341Q9P2D1Espacenet
EP 4641201 A22025-10-2913707Q9P2D1Espacenet
JP 2025517969 A2025-06-1213707Q9P2D1Espacenet
JP 2025032204 A2025-03-1126281Q9P2D1Espacenet
EP 4461818 A22024-11-1326281Q9P2D1Espacenet
JP 2023058610 A2023-04-2526281Q9P2D1Espacenet
JP 2022141755 A2022-09-29291Q9P2D1Espacenet
US 11446398 B22022-09-2015283Q9P2D1Espacenet
JP 2022524081 A2022-04-27118254Q9P2D1Espacenet

1 to 10 of 27

See all 27 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,530

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleCHD7 papersNewest fiscal year
P30CA016672Cancer Center Support Grant92025
T32DC000011Sensory Mechanisms and Disorders92025
P30CA008748Cancer Center Support Grant72025
UL1TR001863Yale Clinical and Translational Science Award72025
R01MH101221Rare Mutations and Autism Spectrum Disorders62025
P51OD011092Support for National Primate Research Center52025
R01CA159859Dysregulation of the Core Binding Factor Complex Inhibits Differentiation and Drives Group 4 Medulloblastoma52025
P01CA096832NORMAL & NEOPLASTIC GROWTH IN THE BRAIN42025
P30CA021765Cancer Center Support Grant (CCSG)42025
P30ES005605Environmental Health Sciences Research Center42025

1 to 10 of 1,530Source NIH's project files

See all 1,530 nih grants

Papers2,784

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Epigenetic role of miR-574 in sperm chromatin remodeling and developmental gene networks in male infertility.Reprod Fertil Dev202642816179PubTator, text miningPubMed
Chromodomain helicase DNA-binding proteins and orofacial cleft.J Res Med Sci202642808081PubTator, text miningPubMed
The Runx1-Gata2 axis: epigenetic architecture of lineage fate.Mol Biol Rep202642801378PubTator, text miningPubMed
A CHD7 intronic variant induces aberrant splicing and structural alterations in the CHD7 DNA-binding domain to cause CHARGE syndrome.Am J Transl Res202642769338PubTator, text miningPubMed
Genetic Heterogeneity of Inborn Errors of Immunity Revealed by Whole-Genome Sequencing: Insights from a Russian Patient Cohort.Int J Mol Sci202642737820PubTator, text miningPubMed
Comprehensive Analysis of Cuproptosis-Related Genes According to Cancer Stage and Their Prognostic Value in Cervical Cancer.Int J Mol Sci202642737631PubTator, text miningPubMed
Case Report: Differential outcomes associated with the same pathogenic variant: long-term follow-up of a CHARGE syndrome case with a nonsense mutation c.6292C>T in the CHD gene.Front Genet202642733771PubTator, text miningPubMed
Dual Aberrant Splicing Caused by an Apparently Missense CHD7 Variant, c.5273A>G (p.Asp1758Gly), in CHARGE Syndrome.Am J Med Genet A202642733123PubTator, text miningPubMed
ATRX Condensates as Candidate Organizers of Enhancer-Centered Nuclear Microenvironments in Neural Progenitors: A Hypothesis for Enhancer-Associated ATRX Function in Neural Progenitors.Bioessays202642725378PubTator, text miningPubMed
Metabolomic analysis of children with congenital heart disease complicated by neurological developmental abnormalities and CHD7 mutations.Front Genet202642725350PubTator, text miningPubMed

1 to 10 of 2,784

See all 2,784 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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