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PRKACA: protein kinase cAMP-activated catalytic subunit alpha
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Gene · 5566

Papers2,763

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

1 to 20 of 2,763

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TitleJournalYearPMIDFound bySource
Screening of Programmed Cell Death-Related Biomarkers and Exploration of Mechanisms in Zhenwu Decoction for Treating Chronic Kidney Disease.Comb Chem High Throughput Screen202642817110PubTator, text miningPubMed
Quercetin, an active component of Qiu's HuaShi decoction, suppresses glycolysis in cervical epithelial cells to reduce HPV infection via modulating the PRKACA/cAMP/PKA/CREB pathway.Biochim Biophys Acta Gen Subj202642805466PubTator, text miningPubMed
A parsimonious three-gene mitochondrial classifier from frontal cortex for Alzheimer's disease: Nested cross-validation and multicenter external validation.J Alzheimers Dis202642742534PubTator, text miningPubMed
Exploring the therapeutic potential of Astragalin in Parkinson's disease: a network pharmacology approach.Ann Med Surg (Lond)202642724825PubTator, text miningPubMed
Association between HOMA-IR and coexisting MASLD and type 2 diabetes: Insights from NHANES and network pharmacology.Ther Adv Endocrinol Metab202642719461PubTator, text miningPubMed
[Fibrolamellar hepatocellular carcinoma: a clinicopathological and molecular genetic analysis of nine cases].Zhonghua Bing Li Xue Za Zhi202642706111PubTator, text miningPubMed
The identification of a PRKACA duplication at 19p13.12 in a female with PPNAD and thyroid carcinoma after a 20-year diagnostic journey.Fam Cancer202642667476PubTator, text miningPubMed
Deciphering the Molecular Basis: Integrative Multi-Method Analysis of Bioactive Constituents and Their Anti-Lung Cancer Mechanisms in Clinical Traditional Chinese Medicine Formulations.Chem Biodivers202642607109PubTator, text miningPubMed
Management of rare primary liver cancers: combined hepato-cholangiocarcinoma and fibrolamellar hepatocellular carcinoma.JHEP Rep202642595050PubTator, text miningPubMed
Hepatoprotective evaluation of benzoylated emodin derivatives: Integrating bioinformatics and in vitro studies.Biomedicine (Taipei)202642555442PubTator, text miningPubMed
TAK1 operates at the primary cilium in non-canonical TGFB/BMP signaling to control heart development.PLoS Biol202642550797PubTator, text miningPubMed
Integrated clinical-genetic-pathological analysis expands the phenotypic and molecular spectrum of PPNAD across carney complex and isolated forms.Eur J Endocrinol202642543523PubTator, text miningPubMed
Network toxicology-driven repurposing of metformin for hepatocellular carcinoma: insights from molecular docking and dynamics simulations.J Mol Model202642470472PubTator, text miningPubMed
Kinome-wide CRISPR/Cas9-knockout screening reveals critical protein kinases in vasopressin V2-receptor signaling.bioRxiv202642465376PubTator, text miningPubMed
Investigation of potential targets and mechanisms of naringenin in the treatment of spinal cord injury: A network pharmacology, molecular docking, and molecular dynamics simulation study.Medicine (Baltimore)202642332524PubTator, text miningPubMed
Functional Precision Oncology in Fibrolamellar Carcinoma: Ex Vivo Identification of Therapeutic Vulnerabilities.Cancers (Basel)202642279327PubTator, text miningPubMed
PKA signaling modulates PRMT5/hnRNP A1-mediated IRES translation and dictates responses to mTOR inhibition in glioblastoma.J Neurooncol202642247073PubTator, text miningPubMed
The DNAJB1-PRKACA Oncogenic Fusion Drives Stepwise Biliary and Pancreatic Carcinogenesis from Intraductal Precursor Lesions.bioRxiv202642244708PubTator, text miningPubMed
Molecular profile of Cushing's syndrome.Vitam Horm202642236012PubTator, text miningPubMed
Primary Pigmented Nodular Adrenocortical Disease Presenting as Osteonecrosis of the Femoral Head: A Case Report.Cureus202642220841PubTator, text miningPubMed

gene-search-2026-11-11-0.2.0

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Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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