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Gene · 55755

CDK5RAP2: CDK5 regulatory subunit associated protein 2

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. CDK5RAP2: CDK5 regulatory subunit associated protein 2. Genes, record 55755. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/55755

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Gene

Symbol
CDK5RAP2
HGNC
Name
CDK5 regulatory subunit associated protein 2
HGNC
NCBI Gene ID
55755
NCBI Gene
HGNC ID
HGNC:18672
HGNC
Ensembl
ENSG00000136861
NCBI Gene
Aliases
C48, CEP215, Cep215, FLJ10867, MCPH3
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q96SN8CDK5 regulatory subunit-associated protein 21,8935Ensembl, GeneID, HGNC

Source UniProt

Patents18

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1440744Q96SN8Espacenet
EP 4650780 A22025-11-196843Q96SN8Espacenet
EP 4641201 A22025-10-296651Q96SN8Espacenet
JP 2025517969 A2025-06-126651Q96SN8Espacenet
JP 2025517970 A2025-06-126843Q96SN8Espacenet
JP 2025032204 A2025-03-1126161Q96SN8Espacenet
EP 4461818 A22024-11-1326161Q96SN8Espacenet
JP 2023058610 A2023-04-2526161Q96SN8Espacenet
US 11446398 B22022-09-2013484Q96SN8Espacenet
JP 2022524081 A2022-04-27116455Q96SN8Espacenet

1 to 10 of 18

See all 18 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants849

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleCDK5RAP2 papersNewest fiscal year
R01NS032457Cell Identity Determination in Human Brain: Somatic Mutation and Cell Lineage72025
ZIABC011459Control of centrosome biogenesis52025
P30CA008748Cancer Center Support Grant42025
P30CA068485Cancer Center Support Grant42025
R01GM074207Analysis of Centrosome Dynamics42025
R35GM130234Chemical Biology of Cell Division42025
P30DK020593Vanderbilt Diabetes Research Center32025
P30DK058404Molecular and Cellular Basis for Digestive Diseases32025
P30EY008126Core Grant in Vision Research32025
P40OD010440Caenorhabditis Genetics Center32025

1 to 10 of 849Source NIH's project files

See all 849 nih grants

Papers1,361

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Divergent microtubule-organizing center strategies in mammalian gametogenesis.Trends Open202642761981PubTator, text miningPubMed
Recent gene duplication and structural remodeling drive rapid lineage-specific gene family evolution in plants.Plant Commun202642693637PubTator, text miningPubMed
Polo/PLK1 phosphorylation relieves Centrosomin/Cnn autoinhibition to promote centrosome scaffold assembly.EMBO J202642533085PubTator, text miningPubMed
Expanding the genetic spectrum of autosomal recessive microcephaly in Pakistani families.BMC Neurol202642249392PubTator, text miningPubMed
SLD5/GINS4 controls dynein-dependent centrosome maturation and exposes a candidate mitotic vulnerability in cancer.bioRxiv202642182163PubTator, text miningPubMed
Rare genetic causes of primary microcephaly in two Saudi families identified via whole-exome sequencing: Genomic and phenotypic delineation of pathogenic CDK5RAP2 and CIT variants.Mol Genet Metab Rep202642079399PubTator, text miningPubMed
NetCrafter: ontology-derived gene network modeling and functional interpretation.Brief Bioinform202641921194PubTator, text miningPubMed
The Role of A-Kinase Anchoring Proteins for Inhibitory cAMP Signalling in Platelets.Cells202641892342PubTator, text miningPubMed
Architects of the Developing Brain: Cytoskeleton-Organizing Molecules in Neurodevelopmental Disorders.Cells202641892327PubTator, text miningPubMed
RSRC2 is a novel RNA-binding protein that safeguards mitotic fidelity by interacting with the lncRNA C1QTNF1-AS1.Nucleic Acids Res202641841495PubTator, text miningPubMed

1 to 10 of 1,361

See all 1,361 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/55755

GET https://conductscience.org/api/genes/v1/55755/patents