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PRKCD: protein kinase C delta

1 protein, 91 patents, 7 drugs, 72 trials, 5,020 NIH grants and 8,978 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolPRKCDHGNC
Nameprotein kinase C deltaHGNC
NCBI Gene ID5580NCBI Gene
HGNC IDHGNC:9399HGNC
EnsemblENSG00000163932NCBI Gene
AliasesALPS3, CVID9, MAY1, PKCD, PKCdelta, PKCδ, nPKC-deltaNCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
Q05655Protein kinase C delta type6762Ensembl, GeneID, HGNCUniProt

Patents 91

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1459724Q05655Espacenet
JP 2026004568 A2026-01-1459725Q05655Espacenet
EP 4650780 A22025-11-195914Q05655Espacenet
EP 4641201 A22025-10-295641Q05655Espacenet
JP 2025517969 A2025-06-125641Q05655Espacenet
JP 2025517970 A2025-06-125914Q05655Espacenet
JP 2025066193 A2025-04-233Q05655Espacenet
JP 2025032204 A2025-03-1134057Q05655Espacenet
JP 2025032204 A2025-03-1134058Q05655Espacenet
EP 4461818 A22024-11-1334057Q05655Espacenet

Drugs 7

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource
CEP-2563CHEMBL6069183Protein kinase C (PKC) inhibitorINHIBITORChEMBL
CEP-2563 DIHYDROCHLORIDECHEMBL6067987Protein kinase C (PKC) inhibitorINHIBITORChEMBL
DELCASERTIBCHEMBL2107872Protein kinase C delta inhibitorINHIBITORChEMBL
GSK-690693CHEMBL494089Protein kinase C (PKC) inhibitorINHIBITORChEMBL
MIDOSTAURINCHEMBL608533Protein kinase C (PKC) inhibitorINHIBITORChEMBL
SOTRASTAURINCHEMBL565612Protein kinase C (PKC) inhibitorINHIBITORChEMBL
UCN-01CHEMBL574737Protein kinase C (PKC) inhibitorINHIBITORChEMBL

Trials 72

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource
NCT07572695MIDOSTAURINClinicalTrials.gov
NCT06313437MIDOSTAURINPHASE1ClinicalTrials.gov
NCT05219266MIDOSTAURINClinicalTrials.gov
NCT04982354MIDOSTAURINPHASE1/PHASE2ClinicalTrials.gov
NCT04496999MIDOSTAURINPHASE1ClinicalTrials.gov
NCT04385290MIDOSTAURINPHASE1/PHASE2ClinicalTrials.gov
NCT04174612MIDOSTAURINPHASE3ClinicalTrials.gov
NCT04097470MIDOSTAURINPHASE2ClinicalTrials.gov
NCT04075747MIDOSTAURINPHASE1ClinicalTrials.gov
NCT04027309MIDOSTAURINPHASE3ClinicalTrials.gov

NIH grants 5020

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA016672Cancer Center Support Grant342,025NIH's project files
P30CA008748Cancer Center Support Grant172,025NIH's project files
P30DK036836Diabetes Research Center142,025NIH's project files
P30ES017885Michigan Center on Lifestage Environmental Exposures and Disease (M-LEEaD)132,025NIH's project files
R01CA031845Synthetic Studies Related to Cancer Research/Treatment132,025NIH's project files
P30CA046934University of Colorado Cancer Center Support Grant122,025NIH's project files
P30CA060553The Robert H. Lurie Comprehensive Cancer Center122,025NIH's project files
R01ES010563Mechanisms of Manganese Neurotoxicity122,025NIH's project files
P30CA016056Roswell Park Cancer Center Support Grant102,025NIH's project files
P30CA068485Cancer Center Support Grant102,025NIH's project files

Papers 8978

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42827077PubTator, text miningPubMed
42810045PubTator, text miningPubMed
42779791PubTator, text miningPubMed
42778874PubTator, text miningPubMed
42758005PubTator, text miningPubMed
42736708PubTator, text miningPubMed
42722701PubTator, text miningPubMed
42702544PubTator, text miningPubMed
42688381PubTator, text miningPubMed
42668075PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license