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Gene · 55818

KDM3A: lysine demethylase 3A

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. KDM3A: lysine demethylase 3A. Genes, record 55818. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/55818

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Gene

Symbol
KDM3A
HGNC
Name
lysine demethylase 3A
HGNC
NCBI Gene ID
55818
NCBI Gene
HGNC ID
HGNC:20815
HGNC
Ensembl
ENSG00000115548
NCBI Gene
Aliases
JHDM2A, JHMD2A, JMJD1, JMJD1A, KIAA0742, TSGA
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q9Y4C1Lysine-specific demethylase 3A1,3210Ensembl, GeneID, HGNC

Source UniProt

Patents31

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1452073Q9Y4C1Espacenet
JP 2026004568 A2026-01-1452074Q9Y4C1Espacenet
JP 2026004568 A2026-01-1452075Q9Y4C1Espacenet
EP 4650780 A22025-11-195509Q9Y4C1Espacenet
EP 4641201 A22025-10-295123Q9Y4C1Espacenet
JP 2025517969 A2025-06-125123Q9Y4C1Espacenet
JP 2025517970 A2025-06-125509Q9Y4C1Espacenet
US 11446398 B22022-09-2047711Q9Y4C1Espacenet
US 11446398 B22022-09-2047712Q9Y4C1Espacenet
US 11446398 B22022-09-2047713Q9Y4C1Espacenet

1 to 10 of 31

See all 31 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,061

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleKDM3A papersNewest fiscal year
P30CA016087Cancer Center Support Grant132025
P30CA046934University of Colorado Cancer Center Support Grant122025
P30CA016672Cancer Center Support Grant72025
P01CA155258Integrative Oncogenomics of Multiple Myeloma52025
P30CA008748Cancer Center Support Grant52025
P30CA016056Roswell Park Cancer Center Support Grant42025
P30CA016058Cancer Center Support Grant42025
P30CA076292Moffitt Cancer Center Support Grant42025
P30CA093373Cancer Center Support Grant P3042025
P30CA168524The University of Kansas Cancer Center42025

1 to 10 of 1,061Source NIH's project files

See all 1,061 nih grants

Papers1,506

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Statement of Retraction: Role of sevoflurane in myocardial ischemia-reperfusion injury via the ubiquitin-specific protease 22/lysine-specific demethylase 3A axis.Bioengineered202642821766PubTator, text miningPubMed
Sex-dependent effects of neonatal hyperoxia on prefrontal cortex development.JCI Insight202642809343PubTator, text miningPubMed
Identification of Novel Transcriptional Alleles in Primary Prostate Cancer Cells and Cancer Stem Cells by Bulk RNA-Seq and Single-Cell RNA-Seq Analyses.Biomolecules202642793173PubTator, text miningPubMed
Chromatin-Based Control of Mammalian Sex Determination: Integrating Epigenetic and Metabolic Mechanisms.Adv Exp Med Biol202642455436PubTator, text miningPubMed
Epigenomic dysregulation in the bone marrow mesenchymal stem cells of acquired aplastic anemia patients: An in silico and in vitro study.Mol Biol Rep202642429854PubTator, text miningPubMed
Visible light reprograms MSCs and T cells into tumor-suppressive states via OPN4-mediated epigenetic remodeling.Acta Pharmacol Sin202642410247PubTator, text miningPubMed
Tanshinone IIA alleviates chronic endometritis via DRAK2 inhibition to restore mitochondrial function and suppress KDM3A-SLC2A3-driven NETs formation.J Mol Histol202642141237PubTator, text miningPubMed
PDK1 elevation was induced by epigenetic modifications of KDM3A and METTL16 to mediate TKI resistance and cancer development.Genes Dis202642004224PubTator, text miningPubMed
KDM3A catalyses the oxidation of acetyl-lysine to hydroxyacetyl-lysine on histone H3K9.Nat Chem202641986689PubTator, text miningPubMed
Mechanism of Cancer-Associated Fibroblasts-Derived NEAT1 Promoting Pancreatic Cancer Cell Stemness via the miR-101-3p/KDM3A Axis.J Biochem Mol Toxicol202641978921PubTator, text miningPubMed

1 to 10 of 1,506

See all 1,506 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/55818

GET https://conductscience.org/api/genes/v1/55818/patents?page=2