Gene · 55818
KDM3A: lysine demethylase 3A
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. KDM3A: lysine demethylase 3A. Genes, record 55818. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/55818
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| Q9Y4C1 | Lysine-specific demethylase 3A | 1,321 | 0 | Ensembl, GeneID, HGNC |
Source UniProt
Patents31
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 52073 | Q9Y4C1 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 52074 | Q9Y4C1 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 52075 | Q9Y4C1 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 5509 | Q9Y4C1 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 5123 | Q9Y4C1 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 5123 | Q9Y4C1 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 5509 | Q9Y4C1 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 47711 | Q9Y4C1 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 47712 | Q9Y4C1 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 47713 | Q9Y4C1 | Espacenet |
1 to 10 of 31
See all 31 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,061
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | KDM3A papers | Newest fiscal year |
|---|---|---|---|
| P30CA016087 | Cancer Center Support Grant | 13 | 2025 |
| P30CA046934 | University of Colorado Cancer Center Support Grant | 12 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 7 | 2025 |
| P01CA155258 | Integrative Oncogenomics of Multiple Myeloma | 5 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 5 | 2025 |
| P30CA016056 | Roswell Park Cancer Center Support Grant | 4 | 2025 |
| P30CA016058 | Cancer Center Support Grant | 4 | 2025 |
| P30CA076292 | Moffitt Cancer Center Support Grant | 4 | 2025 |
| P30CA093373 | Cancer Center Support Grant P30 | 4 | 2025 |
| P30CA168524 | The University of Kansas Cancer Center | 4 | 2025 |
1 to 10 of 1,061Source NIH's project files
See all 1,061 nih grantsPapers1,506
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Statement of Retraction: Role of sevoflurane in myocardial ischemia-reperfusion injury via the ubiquitin-specific protease 22/lysine-specific demethylase 3A axis. | Bioengineered | 2026 | 42821766 | PubTator, text mining | PubMed |
| Sex-dependent effects of neonatal hyperoxia on prefrontal cortex development. | JCI Insight | 2026 | 42809343 | PubTator, text mining | PubMed |
| Identification of Novel Transcriptional Alleles in Primary Prostate Cancer Cells and Cancer Stem Cells by Bulk RNA-Seq and Single-Cell RNA-Seq Analyses. | Biomolecules | 2026 | 42793173 | PubTator, text mining | PubMed |
| Chromatin-Based Control of Mammalian Sex Determination: Integrating Epigenetic and Metabolic Mechanisms. | Adv Exp Med Biol | 2026 | 42455436 | PubTator, text mining | PubMed |
| Epigenomic dysregulation in the bone marrow mesenchymal stem cells of acquired aplastic anemia patients: An in silico and in vitro study. | Mol Biol Rep | 2026 | 42429854 | PubTator, text mining | PubMed |
| Visible light reprograms MSCs and T cells into tumor-suppressive states via OPN4-mediated epigenetic remodeling. | Acta Pharmacol Sin | 2026 | 42410247 | PubTator, text mining | PubMed |
| Tanshinone IIA alleviates chronic endometritis via DRAK2 inhibition to restore mitochondrial function and suppress KDM3A-SLC2A3-driven NETs formation. | J Mol Histol | 2026 | 42141237 | PubTator, text mining | PubMed |
| PDK1 elevation was induced by epigenetic modifications of KDM3A and METTL16 to mediate TKI resistance and cancer development. | Genes Dis | 2026 | 42004224 | PubTator, text mining | PubMed |
| KDM3A catalyses the oxidation of acetyl-lysine to hydroxyacetyl-lysine on histone H3K9. | Nat Chem | 2026 | 41986689 | PubTator, text mining | PubMed |
| Mechanism of Cancer-Associated Fibroblasts-Derived NEAT1 Promoting Pancreatic Cancer Cell Stemness via the miR-101-3p/KDM3A Axis. | J Biochem Mol Toxicol | 2026 | 41978921 | PubTator, text mining | PubMed |
1 to 10 of 1,506
See all 1,506 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/55818
GET https://conductscience.org/api/genes/v1/55818/patents?page=2