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Gene · 55869

Papers3,134

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Pathophysiological significance of impaired KAT7-dependent histone H3K14 acetylation during zinc deficiency.Nat Commun202641702897PubTator, text miningPubMed
T Cell Exhaustion in Hepatocellular Carcinoma: A Substantial Barrier in Immunotherapy.J Cell Mol Med202641645702PubTator, text miningPubMed
Polygonum cognatum Extract: Multitarget Anti-inflammatory, Antidiabetic, and Epigenetic Modulation Properties.ChemistryOpen202641640243PubTator, text miningPubMed
Selective targeting of cortactin tandem repeat acetylation by human lysine deacetylases.FEBS J202641640095PubTator, text miningPubMed
Mucosa-associated bacteria and metabolites in inflammatory bowel disease: from inside to insight.NPJ Biofilms Microbiomes202641617703PubTator, text miningPubMed
Neurogenesis and the Epigenetic Landscape: Role of Histone Modifications and Chromatin Remodeling.Brain Behav202641601423PubTator, text miningPubMed
Metal Preference Hierarchy in the HDAC8 Active Site: A DFT Study.Molecules202641599354PubTator, text miningPubMed
Beyond metabolism: exploring the regulatory and therapeutic implications of lactate and lactylation in cancer-regulated cell death.Cell Death Dis202641571623PubTator, text miningPubMed
Histone and non-histone (de)acetylation impact on the blood-brain barrier.Fluids Barriers CNS202641566325PubTator, text miningPubMed
Cornelia de Lange syndrome: What should a dermatologist know?Adv Clin Exp Med202641499064PubTator, text miningPubMed
Unlocking the therapeutic potential of HDAC8-degrading PROTACs: progress, challenges, and future directions.RSC Med Chem202641497766PubTator, text miningPubMed
Discovery of Histone Deacetylase 8-Specific Proteolysis-Targeting Chimeras with Anticancer Activity against Hematological Malignancies.J Med Chem202641480962PubTator, text miningPubMed
Zinc cofactor in human histone deacetylase 8: Requirement for function and opportunity for drug discovery.Int J Biol Macromol202641443460PubTator, text miningPubMed
Analysis of gene mutation spectrum for early-onset high myopia based on whole-exome sequencing.Br J Ophthalmol202641344850PubTator, text miningPubMed
Curcumae Rhizoma and Sparganii Rhizoma component compatibility exerts an inhibitory effect on endometrial cancer by regulating HDAC8/PTEN/Akt axis.Fitoterapia202641232819PubTator, text miningPubMed
Novel Heterocyclic Compounds Exhibit Potent Antileukemic Activity through Selective Induction of Apoptosis and HDAC8 Interaction in AML Cells.Anticancer Agents Med Chem202640491377PubTator, text miningPubMed
Nitrogen-containing heterocycles as important scaffold for selective and potent HDAC8 inhibition: a step towards effective, non-toxic and selective HDAC8 inhibitor discovery.J Biomol Struct Dyn202639717958PubTator, text miningPubMed
Repurposing of DrugBank molecules as dual non-hydroxamate HDAC8 and HDAC2 inhibitors by pharmacophore modeling, molecular docking, and molecular dynamics studies.J Biomol Struct Dyn202639604351PubTator, text miningPubMed
Smart polymeric nanoparticles for targeted delivery and microenvironment-responsive therapy in pancreatic cancer.Smart Mater Med202541869550PubTator, text miningPubMed
Metformin Increased Histone Deacetylases 1, 3, and 8 Expressions as Epigenetic Regulators in Type 2 Diabetic Patients.Rep Biochem Mol Biol202541531655PubTator, text miningPubMed

gene-search-2026-11-11-0.2.0

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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