Gene · 55869
Papers3,134
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
161 to 180 of 3,134
Download this page as JSON| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Exploration of Hydrazide-Based HDAC8 PROTACs for the Treatment of Hematological Malignancies and Solid Tumors. | J Med Chem | 2024 | 39089850 | PubTator, text mining | PubMed |
| HDAC8 Enhances the Function of HIF-2α by Deacetylating ETS1 to Decrease the Sensitivity of TKIs in ccRCC. | Adv Sci (Weinh) | 2024 | 39073752 | PubTator, text mining | PubMed |
| Mechanism and application of feedback loops formed by mechanotransduction and histone modifications. | Genes Dis | 2024 | 39071110 | PubTator, text mining | PubMed |
| Reversible acetylation of HDAC8 regulates cell cycle. | EMBO Rep | 2024 | 39043961 | PubTator, text mining | PubMed |
| Histone deacetylase 8 promotes innate antiviral immunity through deacetylation of RIG-I. | Front Cell Infect Microbiol | 2024 | 39035358 | PubTator, text mining | PubMed |
| Chitosan-enclosed SLN improved SV-induced hepatocellular cell carcinoma death by modulation of IQGAP gene expression, JNK, and HDAC activities. | Mol Biol Rep | 2024 | 39023688 | PubTator, text mining | PubMed |
| Design and evaluation of nanoscale materials with programmed responsivity towards epigenetic enzymes. | J Mater Chem B | 2024 | 39021201 | PubTator, text mining | PubMed |
| Synthesis and cytotoxic evaluation of heterocyclic compounds by vinylic substitution of ketene dithioacetals. | Chem Biol Drug Des | 2024 | 38997237 | PubTator, text mining | PubMed |
| Discovery of a Highly Potent and Selective HDAC8 Degrader: Advancing the Functional Understanding and Therapeutic Potential of HDAC8. | J Med Chem | 2024 | 38949959 | PubTator, text mining | PubMed |
| Epigenetic modulators provide a path to understanding disease and therapeutic opportunity. | Genes Dev | 2024 | 38914477 | PubTator, text mining | PubMed |
| A Classic Cornelia De Lange Syndrome Type 5 (CdLS5) With a De Novo Missense Variation of p.Gly210Arg in the HDAC8 Gene With a Novel Phenotype of Generalized Dystonia. | Cureus | 2024 | 38910710 | PubTator, text mining | PubMed |
| Rapid Determination of Kinetic Constants for Slow-Binding Inhibitors and Inactivators of Human Histone Deacetylase 8. | Int J Mol Sci | 2024 | 38891780 | PubTator, text mining | PubMed |
| Discovery of a dual-target DYRK2 and HDAC8 inhibitor for the treatment of hepatocellular carcinoma. | Biomed Pharmacother | 2024 | 38889633 | PubTator, text mining | PubMed |
| Unveiling critical structural features for effective HDAC8 inhibition: a comprehensive study using quantitative read-across structure-activity relationship (q-RASAR) and pharmacophore modeling. | Mol Divers | 2024 | 38871969 | PubTator, text mining | PubMed |
| The Importance of Structural Water in HDAC8 for Correct Binding Pose Applied for Drug Design of Anticancer Molecules. | Anticancer Agents Med Chem | 2024 | 38835122 | PubTator, text mining | PubMed |
| Influence of heterochirality on the structure, dynamics, biological properties of cyclic(PFPF) tetrapeptides obtained by solvent-free ball mill mechanosynthesis. | Sci Rep | 2024 | 38834643 | PubTator, text mining | PubMed |
| Replacement of the hydroxamic acid group in the selective HDAC8 inhibitor PCI-34051. | Bioorg Med Chem Lett | 2024 | 38782078 | PubTator, text mining | PubMed |
| Characterization of a novel HDAC2 pathogenetic variant: a missing puzzle piece for chromatinopathies. | Hum Genet | 2024 | 38753158 | PubTator, text mining | PubMed |
| Cornelia de Lange Spectrum. | An Pediatr (Engl Ed) | 2024 | 38735830 | PubTator, text mining | PubMed |
| Protein crotonylation: Basic research and clinical diseases. | Biochem Biophys Rep | 2024 | 38586826 | PubTator, text mining | PubMed |
gene-search-2026-11-11-0.2.0
Sources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
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