Gene · 55872
PBK: PDZ binding kinase
12 sourcesgene-search-2026-11-11-0.2.0
Download JSON
Cite this record
ConductScience Library. PBK: PDZ binding kinase. Genes, record 55872. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/55872
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| Q96KB5 | Lymphokine-activated killer T-cell-originated protein kinase | 322 | 1 | Ensembl, GeneID, HGNC |
Source UniProt
Patents66
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| EP 4641202 A2 | 2025-10-29 | 4778 | Q96KB5 | Espacenet |
| JP 2025024198 A | 2025-02-19 | 14306 | Q96KB5 | Espacenet |
| KR 1020250017231 A | 2025-02-04 | 4778 | Q96KB5 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 61637 | Q96KB5 | Espacenet |
| JP 2022092366 A | 2022-06-22 | 593 | Q96KB5 | Espacenet |
| JP 2022524081 A | 2022-04-27 | 164608 | Q96KB5 | Espacenet |
| JP 2021175409 A | 2021-11-04 | 61 | Q96KB5 | Espacenet |
| US 11078247 B2 | 2021-08-03 | 8161 | Q96KB5 | Espacenet |
| JP 2020062004 A | 2020-04-23 | 999 | Q96KB5 | Espacenet |
| KR 1020190107156 A | 2019-09-18 | 86 | Q96KB5 | Espacenet |
1 to 10 of 66
See all 66 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants784
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | PBK papers | Newest fiscal year |
|---|---|---|---|
| P30CA008748 | Cancer Center Support Grant | 5 | 2025 |
| P30CA016087 | Cancer Center Support Grant | 4 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 4 | 2025 |
| P30CA006973 | Regional Oncology Research Center | 3 | 2025 |
| P30CA023074 | University of Arizona Cancer Center - Cancer Center Support Grant | 3 | 2025 |
| R35CA220500 | Discovering mechanisms of neuroblastoma tumorigenesis to improve patient outcomes | 3 | 2025 |
| P30CA013148 | Comprehensive Cancer Center Support Grant | 2 | 2025 |
| P30CA014599 | Cancer Center Support Grant | 2 | 2025 |
| P30CA015704 | Cancer Center Support Grant | 2 | 2025 |
| P30CA016042 | Cancer Center Support Grant | 2 | 2025 |
1 to 10 of 784Source NIH's project files
See all 784 nih grantsPapers1,726
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| FTU-Seek: Foundation Model-Guided Hard-Negative Learning for Sparse Functional Tissue Unit Segmentation. | Biomedicines | 2026 | 42792676 | PubTator, text mining | PubMed |
| Therapeutic intervention of PBK/TOPK: Bridging cellular signaling to drug discovery. | Pharmacol Res | 2026 | 42790834 | PubTator, text mining | PubMed |
| Gene Expression Biomarkers for Breast Ductal Carcinoma in Situ Recurrence Prediction. | Int J Cancer | 2026 | 42781949 | PubTator, text mining | PubMed |
| PDZ-binding kinase promotes ovarian cancer cell proliferation and invasion via CCNB1 regulation. | Transl Cancer Res | 2026 | 42724446 | PubTator, text mining | PubMed |
| Worenine attenuates pulmonary fibrosis potentially through modulation of PBK/SRC-associated TGF-β1/Smad and NF-κB signaling pathways. | Biomed Pharmacother | 2026 | 42700617 | PubTator, text mining | PubMed |
| A chemoresistance-associated proliferation gene signature identified by single-cell and machine learning analysis predicts prognosis in high-grade serous ovarian carcinoma. | Transl Oncol | 2026 | 42696959 | PubTator, text mining | PubMed |
| RTGNet: A Dual-Branch Network Integrating Recurrent Texture and Temporal Dynamics from sEMG for Lower-Limb Joint Angle Prediction. | Sensors (Basel) | 2026 | 42655451 | PubTator, text mining | PubMed |
| Dual-Target Inhibition of CDK5 and PBK in Pituitary Neuroendocrine Tumors: Mechanisms and Therapeutic Potential. | Genes (Basel) | 2026 | 42650106 | PubTator, text mining | PubMed |
| TCGA-based identification and functional validation of PBK in intrahepatic cholangiocarcinoma progression with involvement of AKT signaling. | Transl Oncol | 2026 | 42594715 | PubTator, text mining | PubMed |
| Evidence for PDZ-Binding Kinase in Lung Disease With an Emphasis on PAH. | Pulm Circ | 2026 | 42516669 | PubTator, text mining | PubMed |
1 to 10 of 1,726
See all 1,726 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/55872
GET https://conductscience.org/api/genes/v1/55872/patents?page=2