Gene · 55876
GSDMB: gasdermin B
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. GSDMB: gasdermin B. Genes, record 55876. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/55876
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| Q8TAX9 | Gasdermin-B | 416 | 11 | Ensembl, GeneID, HGNC |
Source UniProt
Patents17
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 47381 | Q8TAX9 | Espacenet |
| EP 4640849 A2 | 2025-10-29 | 1171 | Q8TAX9 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 7834 | Q8TAX9 | Espacenet |
| WO 2025132695 A1 | 2025-06-26 | 46 | Q8TAX9 | Espacenet |
| JP 2025519096 A | 2025-06-24 | 1171 | Q8TAX9 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 7834 | Q8TAX9 | Espacenet |
| US 11679140 B2 | 2023-06-20 | 29 | Q8TAX9 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 34155 | Q8TAX9 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 34158 | Q8TAX9 | Espacenet |
| JP 2022524081 A | 2022-04-27 | 137126 | Q8TAX9 | Espacenet |
1 to 10 of 17
See all 17 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,184
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | GSDMB papers | Newest fiscal year |
|---|---|---|---|
| ZIAES049019 | Genetic And Environmental Factors In Childhood Respiratory and Allergic Illness | 9 | 2025 |
| T32HL007427 | SYSTEMS APPROACHES TO THE EPIDEMIOLOGY, GENETICS AND GENOMICS OF LUNG DISEASES | 8 | 2025 |
| U19AI070535 | Airway Inflammation and Airway Remodeling in Severe Asthma | 6 | 2025 |
| U19AI077439 | Immune-driven Airway Epithelial Dysfunction in Muco-obstructive Asthma | 6 | 2025 |
| UH3OD023282 | Wisconsin Infant Study Cohort (WISC) ECHO Pediatric Follow-Up | 6 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 5 | 2025 |
| P30DK043351 | Center for the Study of Inflammatory Bowel Disease at Massachusetts General Hospital | 5 | 2025 |
| P30ES006694 | Southwest Environmental Health Sciences Center | 5 | 2025 |
| P30ES007048 | Environmental Exposures, Host Factors and Human Disease | 5 | 2025 |
| U01DK062413 | Determining genomic and host-environment contributions to IBD phenotypes | 5 | 2025 |
1 to 10 of 1,184Source NIH's project files
See all 1,184 nih grantsPapers1,381
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Multi-Ancestry Genome-wide Association Analyses Identify Shared and Specific Genetic Architecture in Mild and Moderate-to-Severe Asthma. | medRxiv | 2026 | 42818167 | PubTator, text mining | PubMed |
| Associations of ASIC2, IKZF3, and GSDMB Variants with Gestational Diabetes Mellitus and Their Interactions with Environmental Exposures Among Chinese Women. | Biomolecules | 2026 | 42793205 | PubTator, text mining | PubMed |
| Unmasking programmed cell death in rhinovirus-driven asthma pathology. | Biochem Soc Trans | 2026 | 42781720 | PubTator, text mining | PubMed |
| Pyroptosis in chronic obstructive pulmonary disease: Beyond the canonical NLRP3/Caspase-1/GSDMD pathway. | Immunol Res | 2026 | 42776308 | PubTator, text mining | PubMed |
| Integrated bioinformatics analyses for GSDMB in carcinogenesis and progression of bladder cancer. | Transl Androl Urol | 2026 | 42729139 | PubTator, text mining | PubMed |
| Structural basis of GSDME pore formation and its regulation by S-palmitoylation. | Proc Natl Acad Sci U S A | 2026 | 42636365 | PubTator, text mining | PubMed |
| Downregulation of GSDMB by EBV-encoded miR-BART12-3p suppresses killer lymphocyte-mediated pyroptosis in gastric cancer cells. | PLoS Pathog | 2026 | 42555663 | PubTator, text mining | PubMed |
| GSDMB as a Therapeutic and Prognostic Target in Clear Cell Renal Cell Carcinoma: Insights From Pyroptosis-Related Gene Analysis. | Front Biosci (Landmark Ed) | 2026 | 42530271 | PubTator, text mining | PubMed |
| Cell Membrane-Modified Lipid Nanoparticle Enhanced Glioblastoma Immunotherapy via Metabolism Reprogramming and Pyroptosis Induction. | Pharmaceutics | 2026 | 42514980 | PubTator, text mining | PubMed |
| Disentangling Shared and Differential Genetic Architectures Between COVID-19 and Other Respiratory Disorders-A Genome-Wide Multi-Omics Framework. | Int J Mol Sci | 2026 | 42511876 | PubTator, text mining | PubMed |
1 to 10 of 1,381
See all 1,381 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/55876
GET https://conductscience.org/api/genes/v1/55876/patents