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Gene · 55879

GABRQ: gamma-aminobutyric acid type A receptor subunit theta

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. GABRQ: gamma-aminobutyric acid type A receptor subunit theta. Genes, record 55879. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/55879

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Gene

Symbol
GABRQ
HGNC
Name
gamma-aminobutyric acid type A receptor subunit theta
HGNC
NCBI Gene ID
55879
NCBI Gene
HGNC ID
HGNC:14454
HGNC
Ensembl
ENSG00000268089
NCBI Gene
Aliases
THETA
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q9UN88Gamma-aminobutyric acid receptor subunit theta6320Ensembl, GeneID, HGNC

Source UniProt

Patents11

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
EP 4650780 A22025-11-1917852Q9UN88Espacenet
EP 4641201 A22025-10-2922130Q9UN88Espacenet
JP 2025517969 A2025-06-1222130Q9UN88Espacenet
JP 2025517970 A2025-06-1217852Q9UN88Espacenet
WO 2025050009 A22025-03-062375Q9UN88Espacenet
US 11446398 B22022-09-2033975Q9UN88Espacenet
US 11400116 B22022-08-024468Q9UN88Espacenet
JP 2022524081 A2022-04-27136946Q9UN88Espacenet
KR 1020210134551 A2021-11-1010Q9UN88Espacenet
KR 1020210105134 A2021-08-2610Q9UN88Espacenet

1 to 10 of 11

See all 11 patents

Drugs76

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource
ABP-700CHEMBL4297255GABA-A receptor; anion channel agonistAGONISTChEMBL
ACAMPROSATECHEMBL1201293GABA-A receptor; anion channel positive modulatorPOSITIVE MODULATORChEMBL
ACAMPROSATE CALCIUMCHEMBL2068724GABA-A receptor; anion channel positive modulatorPOSITIVE MODULATORChEMBL
ADIPIPLONCHEMBL2103791GABA-A receptor; anion channel partial agonistPARTIAL AGONISTChEMBL
ALPRAZOLAMCHEMBL661GABA-A receptor; anion channel positive allosteric modulatorPOSITIVE ALLOSTERIC MODULATORChEMBL
BREXANOLONECHEMBL207538GABA-A receptor; anion channel positive allosteric modulatorPOSITIVE ALLOSTERIC MODULATORChEMBL
BUTABARBITALCHEMBL449GABA-A receptor; anion channel positive allosteric modulatorPOSITIVE ALLOSTERIC MODULATORChEMBL
BUTABARBITAL SODIUMCHEMBL1200982GABA-A receptor; anion channel positive allosteric modulatorPOSITIVE ALLOSTERIC MODULATORChEMBL
BUTALBITALCHEMBL454GABA-A receptor; anion channel positive allosteric modulatorPOSITIVE ALLOSTERIC MODULATORChEMBL
CENOBAMATECHEMBL3989949GABA-A receptor; anion channel positive allosteric modulatorPOSITIVE ALLOSTERIC MODULATORChEMBL

1 to 10 of 76

See all 76 drugs

Trials1,164

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

NIH grants220

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleGABRQ papersNewest fiscal year
P01AG019724Frontotemporal Dementia: Genes, Images, and Emotions32025
ZIAAA000301Integrative genetics of behavior with high throughput technologies32025
P30AG072980Arizona Alzheimer's Disease Research Center22025
UL1TR001863Yale Clinical and Translational Science Award22025
DP1DA054344X chromosome inactivation in sex disparities to substance use disorder12025
K24AG053435Neuropathological changes underlying clinical heterogeneity in Alzheimer disease12025
KL2TR001862Institutional Career Development Core12025
P30AG062422New Approaches to Dementia Heterogeneity12025
P30AG066508Yale Alzheimer Disease Research Center12025
P30CA008748Cancer Center Support Grant12025

1 to 10 of 220Source NIH's project files

See all 220 nih grants

Papers202

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Spatio-molecular gene expression reflects dorsal anterior cingulate cortex structure and function in the human brain.Cell Rep202642241279PubTator, text miningPubMed
EZH2 Inhibition Restores Tumor Suppressor SFRP1 Activity by Reprogramming Extrachromosomal Circular DNA Dynamics in Ovarian Cancer.Biology (Basel)202641744650PubTator, text miningPubMed
Integrated Clinical Genetic Analysis Reveals Transcriptional Neurotransmitter Receptor Dysregulation in Meningiomas Causing Seizure.Neurosurgery202641677355PubTator, text miningPubMed
Non-genetic neuromodulation with graphene optoelectronic actuators for disease models, stem cell maturation, and biohybrid robotics.Nat Commun202540835596PubTator, text miningPubMed
Mitochondrial fission genes MTFP1/MTFP2 as predictive biomarkers in prostate cancer: a mendelian randomization study.Discov Oncol202540824549PubTator, text miningPubMed
Identification of chromatin remodeling-related gene signature to predict the prognosis in breast cancer.Clin Exp Med202540317384PubTator, text miningPubMed
Identification of gene signatures associated with lactation for predicting prognosis and treatment response in breast cancer patients through machine learning.Sci Rep202540253524PubTator, text miningPubMed
Disrupted synaptic gene expression in Fabry disease: Findings from RNA sequencing.Neurobiol Dis202540233852PubTator, text miningPubMed
Towards a precision approach to anesthetic/analgesic immunomodulation in cancer.Front Anesthesiol202440909996PubTator, text miningPubMed
The genetic landscape of autism spectrum disorder in an ancestrally diverse cohort.NPJ Genom Med202439632905PubTator, text miningPubMed

1 to 10 of 202

See all 202 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

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The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/55879

GET https://conductscience.org/api/genes/v1/55879/patents