Gene · 55879
GABRQ: gamma-aminobutyric acid type A receptor subunit theta
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. GABRQ: gamma-aminobutyric acid type A receptor subunit theta. Genes, record 55879. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/55879
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| Q9UN88 | Gamma-aminobutyric acid receptor subunit theta | 632 | 0 | Ensembl, GeneID, HGNC |
Source UniProt
Patents11
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| EP 4650780 A2 | 2025-11-19 | 17852 | Q9UN88 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 22130 | Q9UN88 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 22130 | Q9UN88 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 17852 | Q9UN88 | Espacenet |
| WO 2025050009 A2 | 2025-03-06 | 2375 | Q9UN88 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 33975 | Q9UN88 | Espacenet |
| US 11400116 B2 | 2022-08-02 | 4468 | Q9UN88 | Espacenet |
| JP 2022524081 A | 2022-04-27 | 136946 | Q9UN88 | Espacenet |
| KR 1020210134551 A | 2021-11-10 | 10 | Q9UN88 | Espacenet |
| KR 1020210105134 A | 2021-08-26 | 10 | Q9UN88 | Espacenet |
1 to 10 of 11
See all 11 patentsDrugs76
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
| Drug | ChEMBL ID | Mechanism | Action | Source |
|---|---|---|---|---|
| ABP-700 | CHEMBL4297255 | GABA-A receptor; anion channel agonist | AGONIST | ChEMBL |
| ACAMPROSATE | CHEMBL1201293 | GABA-A receptor; anion channel positive modulator | POSITIVE MODULATOR | ChEMBL |
| ACAMPROSATE CALCIUM | CHEMBL2068724 | GABA-A receptor; anion channel positive modulator | POSITIVE MODULATOR | ChEMBL |
| ADIPIPLON | CHEMBL2103791 | GABA-A receptor; anion channel partial agonist | PARTIAL AGONIST | ChEMBL |
| ALPRAZOLAM | CHEMBL661 | GABA-A receptor; anion channel positive allosteric modulator | POSITIVE ALLOSTERIC MODULATOR | ChEMBL |
| BREXANOLONE | CHEMBL207538 | GABA-A receptor; anion channel positive allosteric modulator | POSITIVE ALLOSTERIC MODULATOR | ChEMBL |
| BUTABARBITAL | CHEMBL449 | GABA-A receptor; anion channel positive allosteric modulator | POSITIVE ALLOSTERIC MODULATOR | ChEMBL |
| BUTABARBITAL SODIUM | CHEMBL1200982 | GABA-A receptor; anion channel positive allosteric modulator | POSITIVE ALLOSTERIC MODULATOR | ChEMBL |
| BUTALBITAL | CHEMBL454 | GABA-A receptor; anion channel positive allosteric modulator | POSITIVE ALLOSTERIC MODULATOR | ChEMBL |
| CENOBAMATE | CHEMBL3989949 | GABA-A receptor; anion channel positive allosteric modulator | POSITIVE ALLOSTERIC MODULATOR | ChEMBL |
1 to 10 of 76
See all 76 drugsTrials1,164
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
| Trial | Drug | Phase | Results first posted | Source |
|---|---|---|---|---|
| NCT07602400 | SEVOFLURANE | ClinicalTrials.gov | ||
| NCT07602400 | PROPOFOL | ClinicalTrials.gov | ||
| NCT07588750 | TOPIRAMATE | ClinicalTrials.gov | ||
| NCT07584902 | CIPEPOFOL | ClinicalTrials.gov | ||
| NCT07584902 | PROPOFOL | ClinicalTrials.gov | ||
| NCT07569198 | MIDAZOLAM | PHASE2 | ClinicalTrials.gov | |
| NCT07568938 | DESFLURANE | ClinicalTrials.gov | ||
| NCT07560878 | LORAZEPAM | EARLY_PHASE1 | ClinicalTrials.gov | |
| NCT07532733 | PROPOFOL | ClinicalTrials.gov | ||
| NCT07513870 | SEVOFLURANE | ClinicalTrials.gov |
1 to 10 of 1,164
See all 1,164 trialsNIH grants220
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | GABRQ papers | Newest fiscal year |
|---|---|---|---|
| P01AG019724 | Frontotemporal Dementia: Genes, Images, and Emotions | 3 | 2025 |
| ZIAAA000301 | Integrative genetics of behavior with high throughput technologies | 3 | 2025 |
| P30AG072980 | Arizona Alzheimer's Disease Research Center | 2 | 2025 |
| UL1TR001863 | Yale Clinical and Translational Science Award | 2 | 2025 |
| DP1DA054344 | X chromosome inactivation in sex disparities to substance use disorder | 1 | 2025 |
| K24AG053435 | Neuropathological changes underlying clinical heterogeneity in Alzheimer disease | 1 | 2025 |
| KL2TR001862 | Institutional Career Development Core | 1 | 2025 |
| P30AG062422 | New Approaches to Dementia Heterogeneity | 1 | 2025 |
| P30AG066508 | Yale Alzheimer Disease Research Center | 1 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 1 | 2025 |
1 to 10 of 220Source NIH's project files
See all 220 nih grantsPapers202
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Spatio-molecular gene expression reflects dorsal anterior cingulate cortex structure and function in the human brain. | Cell Rep | 2026 | 42241279 | PubTator, text mining | PubMed |
| EZH2 Inhibition Restores Tumor Suppressor SFRP1 Activity by Reprogramming Extrachromosomal Circular DNA Dynamics in Ovarian Cancer. | Biology (Basel) | 2026 | 41744650 | PubTator, text mining | PubMed |
| Integrated Clinical Genetic Analysis Reveals Transcriptional Neurotransmitter Receptor Dysregulation in Meningiomas Causing Seizure. | Neurosurgery | 2026 | 41677355 | PubTator, text mining | PubMed |
| Non-genetic neuromodulation with graphene optoelectronic actuators for disease models, stem cell maturation, and biohybrid robotics. | Nat Commun | 2025 | 40835596 | PubTator, text mining | PubMed |
| Mitochondrial fission genes MTFP1/MTFP2 as predictive biomarkers in prostate cancer: a mendelian randomization study. | Discov Oncol | 2025 | 40824549 | PubTator, text mining | PubMed |
| Identification of chromatin remodeling-related gene signature to predict the prognosis in breast cancer. | Clin Exp Med | 2025 | 40317384 | PubTator, text mining | PubMed |
| Identification of gene signatures associated with lactation for predicting prognosis and treatment response in breast cancer patients through machine learning. | Sci Rep | 2025 | 40253524 | PubTator, text mining | PubMed |
| Disrupted synaptic gene expression in Fabry disease: Findings from RNA sequencing. | Neurobiol Dis | 2025 | 40233852 | PubTator, text mining | PubMed |
| Towards a precision approach to anesthetic/analgesic immunomodulation in cancer. | Front Anesthesiol | 2024 | 40909996 | PubTator, text mining | PubMed |
| The genetic landscape of autism spectrum disorder in an ancestrally diverse cohort. | NPJ Genom Med | 2024 | 39632905 | PubTator, text mining | PubMed |
1 to 10 of 202
See all 202 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/55879
GET https://conductscience.org/api/genes/v1/55879/patents