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MAPK9: mitogen-activated protein kinase 9

1 protein, 37 patents, 3 drugs, 4 trials, 4,976 NIH grants and 9,794 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolMAPK9HGNC
Namemitogen-activated protein kinase 9HGNC
NCBI Gene ID5601NCBI Gene
HGNC IDHGNC:6886HGNC
EnsemblENSG00000050748NCBI Gene
AliasesJNK-55, JNK2, JNK2A, JNK2ALPHA, JNK2B, JNK2BETA, PRKM9, SAPK, SAPK1a, p54a, p54aSAPKNCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P45984Mitogen-activated protein kinase 94245Ensembl, GeneID, HGNCUniProt

Patents 37

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1453953P45984Espacenet
EP 4650780 A22025-11-1912665P45984Espacenet
JP 2025524002 A2025-07-2535P45984Espacenet
JP 2025517970 A2025-06-1212665P45984Espacenet
KR 1020250039465 A2025-03-2035P45984Espacenet
EP 4484957 A12025-01-01147P45984Espacenet
JP 2024023699 A2024-02-2135P45984Espacenet
JP 2024505890 A2024-02-0835P45984Espacenet
US 11892452 B22024-02-0643P45984Espacenet
US 11892452 B22024-02-06102P45984Espacenet

Drugs 3

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource
BENTAMAPIMODCHEMBL3545213c-Jun N-terminal kinase, JNK inhibitorINHIBITORChEMBL
CC-401CHEMBL1614713c-Jun N-terminal kinase 2 inhibitorINHIBITORChEMBL
TANZISERTIBCHEMBL1950289c-Jun N-terminal kinase 2 inhibitorINHIBITORChEMBL

Trials 4

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource
NCT01630252BENTAMAPIMODPHASE2ClinicalTrials.gov
NCT01466725TANZISERTIBPHASE2ClinicalTrials.gov
NCT01203943TANZISERTIBPHASE2ClinicalTrials.gov
NCT00126893CC-401PHASE1ClinicalTrials.gov

NIH grants 4976

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA016672Cancer Center Support Grant642,025NIH's project files
P30CA008748Cancer Center Support Grant152,025NIH's project files
P30CA016058Cancer Center Support Grant102,025NIH's project files
P30ES009089Center for Environmental Health in Northern Manhattan102,025NIH's project files
P30CA125123Baylor College of Medicine Cancer Center - Cancer Center Support Grant92,025NIH's project files
P30CA060553The Robert H. Lurie Comprehensive Cancer Center82,025NIH's project files
R01AG044034Oxidative Stress and the Development of Osteoarthritis82,025NIH's project files
R01EY011500Structure-function studies of visual arrestin82,025NIH's project files
P30CA016087Cancer Center Support Grant72,025NIH's project files
P30CA022453CANCER CENTER SUPPORT GRANT72,025NIH's project files

Papers 9794

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42734271PubTator, text miningPubMed
42721096PubTator, text miningPubMed
42676063PubTator, text miningPubMed
42612267PubTator, text miningPubMed
42578037PubTator, text miningPubMed
42570848PubTator, text miningPubMed
42533549PubTator, text miningPubMed
42481337PubTator, text miningPubMed
42468874PubTator, text miningPubMed
42467925PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license