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Gene · 5603

MAPK13: mitogen-activated protein kinase 13

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. MAPK13: mitogen-activated protein kinase 13. Genes, record 5603. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/5603

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Gene

Symbol
MAPK13
HGNC
Name
mitogen-activated protein kinase 13
HGNC
NCBI Gene ID
5603
NCBI Gene
HGNC ID
HGNC:6875
HGNC
Ensembl
ENSG00000156711
NCBI Gene
Aliases
MAPK 13, MAPK-13, PRKM13, SAPK4, p38delta
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
O15264Mitogen-activated protein kinase 133658Ensembl, GeneID, HGNC

Source UniProt

Patents76

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
US 12539325 B22026-02-0351O15264Espacenet
EP 4618968 A12025-09-2433O15264Espacenet
US 12252709 B22025-03-1827O15264Espacenet
US 12133879 B22024-11-0551O15264Espacenet
JP 2024123008 A2024-09-107036O15264Espacenet
US 11920164 B22024-03-0545O15264Espacenet
US 11892452 B22024-02-06121O15264Espacenet
US 11872193 B22024-01-1651O15264Espacenet
KR 1020230031998 A2023-03-0727O15264Espacenet
US 11446398 B22022-09-2052380O15264Espacenet

1 to 10 of 76

See all 76 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,303

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleMAPK13 papersNewest fiscal year
P30CA016672Cancer Center Support Grant92025
P30CA134274UNIVERSITY OF MARYLAND GREENEBAUM CANCER CENTERSUPPORT GRANT82025
R35HL145242Defining and Controlling Airway Disease82025
R01GM086858New Molecular Probes For Protein Kinases72025
P30CA033572Cancer Center Support Grant52025
P30CA068485Cancer Center Support Grant42025
P30DK058404Molecular and Cellular Basis for Digestive Diseases42025
R01AA015407Endoplasmic Reticulum Stress and Alcohol Neurotoxicity42025
R35CA197589Inducing Proximity: An Emerging Paradigm for New Therapeutic Modalities42025
P01CA116087H. pylori-induced Inflammation and Gastric Cancer32025

1 to 10 of 1,303Source NIH's project files

See all 1,303 nih grants

Papers1,919

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Tri-Combination Antiretroviral Therapy Induces Dose- and Time-Dependent Disruption of Intestinal Epithelial Barrier Function and Repair Responses in Human T84 Cells.J Xenobiot202642783603PubTator, text miningPubMed
Expression and Localization of AKT1, MAPK13, STAT1 and TLR4 in Lung Tissues From Patients With Asthma, COPD and Asthma-COPD Overlap.Arch Bronconeumol202642754503PubTator, text miningPubMed
Thinking Outside the Binding Site: A Self-Encapsulating Kinase Inhibitor Remodels Its Pocket to Achieve Selectivity.Angew Chem Int Ed Engl202642745179PubTator, text miningPubMed
Comparative Phytochemical and Antiviral Characteristics of Dipsacus asperoides and Phlomis umbrosa Against Influenza A Virus: LC-QTOF-MS Profiling and Exploratory Network Pharmacology.Plants (Basel)202642739416PubTator, text miningPubMed
Association between HOMA-IR and coexisting MASLD and type 2 diabetes: Insights from NHANES and network pharmacology.Ther Adv Endocrinol Metab202642719461PubTator, text miningPubMed
Unveiling the neurodevelopmental toxicity of PFOA and PFOS: evidence from integration of in silico and in vitro study.Toxicol Mech Methods202642634987PubTator, text miningPubMed
A TMED3-governed disulfidptosis-related diagnostic signature reveals tumor microenvironment remodeling in intrahepatic cholangiocarcinoma.Front Immunol202642591673PubTator, text miningPubMed
Exosomal lncRNA PVT1 promotes fibroblast activation and colon cancer progression via miR-23b-5p signaling.J Pathol202642535319PubTator, text miningPubMed
A Network Pharmacology Review of Plant-Derived Anticancer Compounds in Lung, Breast, Colorectal and Prostate Cancer.Int J Mol Sci202642511521PubTator, text miningPubMed
Integrative analysis identifies candidate biomarkers for bladder cancer: evidence from genomic and clinical validation.Mol Biol Rep202642470583PubTator, text miningPubMed

1 to 10 of 1,919

See all 1,919 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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The record and each of its lists are JSON, twenty rows a page. No key.

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