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MAP2K7: mitogen-activated protein kinase kinase 7

1 protein, 32 patents, 0 drugs, 0 trials, 18,330 NIH grants and 56,434 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolMAP2K7HGNC
Namemitogen-activated protein kinase kinase 7HGNC
NCBI Gene ID5609NCBI Gene
HGNC IDHGNC:6847HGNC
EnsemblENSG00000076984NCBI Gene
AliasesJNKK2, Jnkk2, MAPKK7, MEK, MEK 7, MKK7, PRKMK7, SAPKK-4, SAPKK4NCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
O14733Dual specificity mitogen-activated protein kinase kinase 741937Ensembl, GeneID, HGNCUniProt

Patents 32

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
EP 4650780 A22025-11-1911550O14733Espacenet
EP 4641201 A22025-10-2912110O14733Espacenet
JP 2025524002 A2025-07-2526O14733Espacenet
JP 2025517969 A2025-06-1212110O14733Espacenet
JP 2025517970 A2025-06-1211550O14733Espacenet
KR 1020250039465 A2025-03-2026O14733Espacenet
JP 2024023699 A2024-02-2126O14733Espacenet
JP 2024505890 A2024-02-0826O14733Espacenet
JP 2023509886 A2023-03-1026O14733Espacenet
US 11564998 B22023-01-317008O14733Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 18330

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA016672Cancer Center Support Grant7252,025NIH's project files
P30CA008748Cancer Center Support Grant6502,025NIH's project files
P30CA076292Moffitt Cancer Center Support Grant1312,025NIH's project files
P30CA010815Consolidated Basic Cancer Research Program1202,025NIH's project files
P30CA006973Regional Oncology Research Center1082,025NIH's project files
P30CA046934University of Colorado Cancer Center Support Grant1052,025NIH's project files
P30CA068485Cancer Center Support Grant942,025NIH's project files
P30CA016058Cancer Center Support Grant912,025NIH's project files
UL1TR001863Yale Clinical and Translational Science Award752,025NIH's project files
P30CA006927Comprehensive Cancer Center Program at Fox Chase662,025NIH's project files

Papers 56434

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42826809PubTator, text miningPubMed
42825158PubTator, text miningPubMed
42824961PubTator, text miningPubMed
42824816PubTator, text miningPubMed
42823486PubTator, text miningPubMed
42820191PubTator, text miningPubMed
42820076PubTator, text miningPubMed
42816108PubTator, text miningPubMed
42814864PubTator, text miningPubMed
42814800PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license