Gene · 5618
PRLR: prolactin receptor
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. PRLR: prolactin receptor. Genes, record 5618. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/5618
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| P16471 | Prolactin receptor | 622 | 12 | Ensembl, GeneID, HGNC |
Source UniProt
Patents106
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| EP 4745230 A2 | 2026-05-20 | 29 | P16471 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 59166 | P16471 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 18735 | P16471 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 23351 | P16471 | Espacenet |
| EP 4633648 A1 | 2025-10-22 | 47 | P16471 | Espacenet |
| JP 2025147176 A | 2025-10-06 | 10821 | P16471 | Espacenet |
| JP 2025529142 A | 2025-09-04 | 3577 | P16471 | Espacenet |
| JP 2025529142 A | 2025-09-04 | 7435 | P16471 | Espacenet |
| US 12371689 B2 | 2025-07-29 | 3577 | P16471 | Espacenet |
| US 12371689 B2 | 2025-07-29 | 7435 | P16471 | Espacenet |
1 to 10 of 106
See all 106 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,392
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | PRLR papers | Newest fiscal year |
|---|---|---|---|
| P30CA056036 | Translational Research in Cancer | 15 | 2025 |
| P30CA014520 | UW Comprehensive Cancer Center Support | 9 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 8 | 2025 |
| P30DK020593 | Vanderbilt Diabetes Research Center | 8 | 2025 |
| P30CA046934 | University of Colorado Cancer Center Support Grant | 5 | 2025 |
| P30CA051008 | Georgetown University Lombardi Comprehensive Cancer Center Support Grant | 5 | 2025 |
| P30CA168524 | The University of Kansas Cancer Center | 5 | 2025 |
| P30DK020572 | Michigan Diabetes Research Center (MDRC) | 4 | 2025 |
| R01AG059779 | Combining GHR antagonism with life extending compounds: a search for synergies | 4 | 2025 |
| R01DK067536 | Role of IGF-1 and insulin receptors beta-cell survival | 4 | 2025 |
1 to 10 of 1,392Source NIH's project files
See all 1,392 nih grantsPapers2,965
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Stress Biology in Cancer: Neuroendocrine-Immune Mechanisms Linking Tumor Progression to Translational Interventions. | Cancer Commun (Lond) | 2026 | 42774376 | PubTator, text mining | PubMed |
| Concurrent human epidermal growth factor receptor 2-positive breast cancer with axillary nodal metastasis in a patient with pituitary prolactinoma: a case report. | AME Case Rep | 2026 | 42592430 | PubTator, text mining | PubMed |
| Prolactin as a Candidate Biomarker in Non-Small Cell Lung Cancer: Implications for Personalized Medicine and Post-Treatment Risk Stratification. | J Pers Med | 2026 | 42506069 | PubTator, text mining | PubMed |
| Prolactin as an immuno-neuroendocrine integrator: linking immune homeostasis, hematopoietic dynamics and iron metabolism. | Mol Biol Rep | 2026 | 42467144 | PubTator, text mining | PubMed |
| Prolactin receptor overexpression in pregnancy-associated Cushing syndrome and functional implications. | JCEM Case Rep | 2026 | 42395055 | PubTator, text mining | PubMed |
| Identification of Differentially Expressed Genes in Non-functioning Pituitary Adenoma by Transcriptome Analysis. | In Vivo | 2026 | 42379758 | PubTator, text mining | PubMed |
| Emerging pharmacotherapies for androgenetic alopecia. | Expert Opin Pharmacother | 2026 | 42290527 | PubTator, text mining | PubMed |
| Idiopathic granulomatous mastitis as an autoimmune disease: A review of immunopathogenesis and therapeutic response. | Autoimmun Rev | 2026 | 42173230 | PubTator, text mining | PubMed |
| Single-cell analysis reveals that NRG1/3-ERBB4 signaling affects metabolic reprogramming and immune escape in Wilms tumor. | Biol Direct | 2026 | 42163376 | PubTator, text mining | PubMed |
| Molecular insights into the PRLR-Hippo-YAP axis in breast cancer therapeutics. | Expert Opin Ther Targets | 2026 | 42096243 | PubTator, text mining | PubMed |
1 to 10 of 2,965
See all 2,965 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/5618
GET https://conductscience.org/api/genes/v1/5618/patents?page=2