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Gene · 5618

PRLR: prolactin receptor

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. PRLR: prolactin receptor. Genes, record 5618. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/5618

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Gene

Symbol
PRLR
HGNC
Name
prolactin receptor
HGNC
NCBI Gene ID
5618
NCBI Gene
HGNC ID
HGNC:9446
HGNC
Ensembl
ENSG00000113494
NCBI Gene
Aliases
HPRL, MFAB, RI-PRLR, hPRLrI
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P16471Prolactin receptor62212Ensembl, GeneID, HGNC

Source UniProt

Patents106

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
EP 4745230 A22026-05-2029P16471Espacenet
JP 2026004568 A2026-01-1459166P16471Espacenet
EP 4650780 A22025-11-1918735P16471Espacenet
EP 4641201 A22025-10-2923351P16471Espacenet
EP 4633648 A12025-10-2247P16471Espacenet
JP 2025147176 A2025-10-0610821P16471Espacenet
JP 2025529142 A2025-09-043577P16471Espacenet
JP 2025529142 A2025-09-047435P16471Espacenet
US 12371689 B22025-07-293577P16471Espacenet
US 12371689 B22025-07-297435P16471Espacenet

1 to 10 of 106

See all 106 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,392

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitlePRLR papersNewest fiscal year
P30CA056036Translational Research in Cancer152025
P30CA014520UW Comprehensive Cancer Center Support92025
P30CA016672Cancer Center Support Grant82025
P30DK020593Vanderbilt Diabetes Research Center82025
P30CA046934University of Colorado Cancer Center Support Grant52025
P30CA051008Georgetown University Lombardi Comprehensive Cancer Center Support Grant52025
P30CA168524The University of Kansas Cancer Center52025
P30DK020572Michigan Diabetes Research Center (MDRC)42025
R01AG059779Combining GHR antagonism with life extending compounds: a search for synergies42025
R01DK067536Role of IGF-1 and insulin receptors beta-cell survival42025

1 to 10 of 1,392Source NIH's project files

See all 1,392 nih grants

Papers2,965

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Stress Biology in Cancer: Neuroendocrine-Immune Mechanisms Linking Tumor Progression to Translational Interventions.Cancer Commun (Lond)202642774376PubTator, text miningPubMed
Concurrent human epidermal growth factor receptor 2-positive breast cancer with axillary nodal metastasis in a patient with pituitary prolactinoma: a case report.AME Case Rep202642592430PubTator, text miningPubMed
Prolactin as a Candidate Biomarker in Non-Small Cell Lung Cancer: Implications for Personalized Medicine and Post-Treatment Risk Stratification.J Pers Med202642506069PubTator, text miningPubMed
Prolactin as an immuno-neuroendocrine integrator: linking immune homeostasis, hematopoietic dynamics and iron metabolism.Mol Biol Rep202642467144PubTator, text miningPubMed
Prolactin receptor overexpression in pregnancy-associated Cushing syndrome and functional implications.JCEM Case Rep202642395055PubTator, text miningPubMed
Identification of Differentially Expressed Genes in Non-functioning Pituitary Adenoma by Transcriptome Analysis.In Vivo202642379758PubTator, text miningPubMed
Emerging pharmacotherapies for androgenetic alopecia.Expert Opin Pharmacother202642290527PubTator, text miningPubMed
Idiopathic granulomatous mastitis as an autoimmune disease: A review of immunopathogenesis and therapeutic response.Autoimmun Rev202642173230PubTator, text miningPubMed
Single-cell analysis reveals that NRG1/3-ERBB4 signaling affects metabolic reprogramming and immune escape in Wilms tumor.Biol Direct202642163376PubTator, text miningPubMed
Molecular insights into the PRLR-Hippo-YAP axis in breast cancer therapeutics.Expert Opin Ther Targets202642096243PubTator, text miningPubMed

1 to 10 of 2,965

See all 2,965 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/5618

GET https://conductscience.org/api/genes/v1/5618/patents?page=2